Sh2 and 3 domains Study guides, Revision notes & Summaries

CPPS EXAM PRACTICE QUESTIONS WITH CORRECT ANSWERS 2023/2024 (Graded). What isSH1 domain characterized by? - Correct Answer-Catalytic domain of a protein, for example the receptor. and it has the kinase activity. It is responsible for phosphorylating tyrosine residues. What is SH2 domain characterized by? - Correct Answer-Binds peptides with consensus (positional information on C-terminal side of the phosphorylated tyrosine). Very specific. Mediates protein-protein interactions in cellular ...

CPPS 325 FINAL EXAM WITH 100% CORRECT ANSWERS 2023/2024 Graded A+. What are the 5 well-known enzyme-linked cell surface receptors? - Correct Answer-1. Receptor Guanylyl Cyclase: produces cGMP 2. RTK: phosphorylate tyrosine residues leading to association of signalling molecules and cascade 3. TK Associated Receptors: associate with proteins having TK activity 4. Receptor Tyrosine Phosphates: Removes phosphate on tyrosine residues 5. Receptor Serine/Threonine Kinases: phosphorylate specific...

CPPS 325 FINAL EXAM QUESTIONS WITH CORRECT ANSWERS 2023/2024 Graded A+. What is the only example of conformational change activation? - Correct Answer-Insulin receptor kinase. All other RTKs are activated through forms of dimerization. What are the two forms of dimerization? - Correct Answer-i) Receptors exist as unactivated dimers until ligand binds (Twist theory) ii) exist as monomers that are brought together and activated by ligand binding. What is the most common method of dimerizatio...

CPPS 325 FINAL EXAM Questions and Answers 2023 What are the 5 well-known enzyme-linked cell surface receptors? 1. Receptor Guanylyl Cyclase: produces cGMP 2. RTK: phosphorylate tyrosine residues leading to association of signalling molecules and cascade 3. TK Associated Receptors: associate with proteins having TK activity 4. Receptor Tyrosine Phosphates: Removes phosphate on tyrosine residues 5. Receptor Serine/Threonine Kinases: phosphorylate specific Serine/Threonine residues on IC sign...

What are the 5 well-known enzyme-linked cell surface receptors? - 1. Receptor Guanylyl Cyclase: produces cGMP 2. RTK: phosphorylate tyrosine residues leading to association of signalling molecules and cascade 3. TK Associated Receptors: associate with proteins having TK activity 4. Receptor Tyrosine Phosphates: Removes phosphate on tyrosine residues 5. Receptor Serine/Threonine Kinases: phosphorylate specific Serine/Threonine residues on IC signalling molecules How are RTK and TK Ass...

MICR 460 Microbiology Final Exam Questions and Answers Latest (Graded) Antigen is typically found extracellularly and intracellularly within the cytosol and endosomes A 2. CD8 T cells obtain ITAM phosphorylation before CD4 T cells do during an immune response B 3. Epithelial cells first develop in bone marrow but finish their development in the thymus B 4. ELISAs measure soluble protein antigen A 5. FACS analysis can distinguish different Lin+ cell types but not Lin- cells types because Lin...

CPPS 325 FINAL EXAM Questions and answers rated A+ 2023What are the 5 well-known enzyme-linked cell surface receptors? 1. Receptor Guanylyl Cyclase: produces cGMP 2. RTK: phosphorylate tyrosine residues leading to association of signalling molecules and cascade 3. TK Associated Receptors: associate with proteins having TK activity 4. Receptor Tyrosine Phosphates: Removes phosphate on tyrosine residues 5. Receptor Serine/Threonine Kinases: phosphorylate specific Serine/Threonine residues on...

MICR 460 Microbiology Final Exam Questions and Answers Latest (Graded) Antigen is typically found extracellularly and intracellularly within the cytosol and endosomes A 2. CD8 T cells obtain ITAM phosphorylation before CD4 T cells do during an immune response B 3. Epithelial cells first develop in bone marrow but finish their development in the thymus B 4. ELISAs measure soluble protein antigen A 5. FACS analysis can distinguish different Lin+ cell types but not Lin- cells types because Lin...

CPPS FINAL EXAM Practice Questions WITH CORRECT ANSWERS Graded A+ | 2023/2024. What is the importance of RBD in Raf activation? - Correct Answer-It is the N-terminal regulatory domain of the Raf protein. The RBD needs to interact with RasGTP to enable activaiton of Raf. Interaction of RBD with RasGTP at the membrane destabilizes Raf interaction with 14-3-3. This allows for PP2A to dephosphorylate Raf phosphoserines (the locks on the inactive state). What is RBD? - Correct Answer-Ras Binding...

Quiz questions based on Lecture 13 (Signaling-1). 1. What is always present in a signaling pathway? A. Signal that originates outside a cell B. Signal that remains outside the responding cell during signaling C. Cell-surface receptor D. A and B are correct 2. Adrenaline is a signal used in the fight-or flight response. Adrenaline signaling is A. Endocrine B. Paracrine C. Autocrine D. Contact-dependent 3. One signal can have different effects on the same cell; for example, it can alter...