Carboplatin Study guides, Revision notes & Summaries

A comprehensive geriatric assessment (CGA) is a multidisciplinary evaluation to assess life expectancy and risk of morbidity and mortality in the older patient. This assessment tool would evaluate and include the following areas: functional status, socioeconomic issues, psychosocial Neoadjuvant therapy does not increase survival when compared to adjuvant therapy. It only changes the timing of treatment and can change surgical options if the tumor is shrunk enough. If this occurs, the patient may...

Neoadjuvant therapy does not increase survival when compared to adjuvant therapy. It only changes the timing of treatment and can change surgical options if the tumor is shrunk enough. If this occurs, the patient may only require a lumpectomy plus radiation therapy instead of needing a mastectomy - correct answerMain benefit of neoadjuvant chemotherapy (breast cancer patient) A comprehensive geriatric assessment (CGA) is a multidisciplinary evaluation to assess life expectancy and risk of mor...

3 major phases of cell division: Interphase Mitotic phase Cytokinesis 3 steps of interphase: First growth phase (G1) Synthesis phase (S phase) Second growth phase (G2) 4 phases of mitosis: Prophase Metaphase Anaphase Telophase Innate immunity: Non-specific response, either: 1. Barrier (skin, mucous membranes, flora of skin/gut) 2. Cellular components (phagocytes, natural killer cells, granulocytes, macrophages) Adaptive immunity: Follows innate immunity ...

Neoadjuvant therapy does not increase survival when compared to adjuvant therapy. It only changes the timing of treatment and can change surgical options if the tumor is shrunk enough. If this occurs, the patient may only require a lumpectomy plus radiation therapy instead of needing a mastectomy Main benefit of neoadjuvant chemotherapy (breast cancer patient) A comprehensive geriatric assessment (CGA) is a multidisciplinary evaluation to assess life expectancy and risk of morbidity and ...

Neoadjuvant therapy does not increase survival when compared to adjuvant therapy. It only changes the timing of treatment and can change surgical options if the tumor is shrunk enough. If this occurs, the patient may only require a lumpectomy plus radiation therapy instead of needing a mastectomy - CORRECT ANS Main benefit of neoadjuvant chemotherapy (breast cancer patient) A comprehensive geriatric assessment (CGA) is a multidisciplinary evaluation to assess life expectancy and risk of mo...

Totect Correct Answer Anecdote for Doxorubicin Warm Compress Correct Answer Plant alkaloids and etoposide Bleomycin Correct Answer bad for the lungs Leucovorin Correct Answer potentiates the effects of 5-FU and decreases the effect of MTX Calvert Formula Components Correct Answer Area under the curve (AUC) Carboplatin Creatinine Clearance Aromatase Inhibitors Correct Answer used for postmenopausal women- osteoporosis Vesicant Administration Correct Answer Prior to non-vesican...

Chemotherapy regimens that commonly cause delayed N/V - Answer- Cisplatin, Carboplatin, Cyclphosphamide Most effective treatment for delayed N/V - Answer- Reglan (metoclopramide) and Dexamethasone Capcitabine (Xeloda) is used in these types of cancer - Answer- Colon, Rectal, Breast, Stomach, Pancreatic, Esophageal Side effects of Xeloda - Answer- Diarrhea, nausea, vomiting, mouth sores Generic name of Xeloda - Answer- Capecitabine Mouth sores occur this many days after chemo - Ans...

Neoadjuvant therapy does not increase survival when compared to adjuvant therapy. It only changes the timing of treatment and can change surgical options if the tumor is shrunk enough. If this occurs, the patient may only require a lumpectomy plus radiation therapy instead of needing a mastectomy - ANSWER Main benefit of neoadjuvant chemotherapy (breast cancer patient) A comprehensive geriatric assessment (CGA) is a multidisciplinary evaluation to assess life expectancy and risk of morbidity ...

Doxorubicin Cardiotoxic TISSUE VESICANT Baseline MUGA and total dose (CONCERN at 550 mg/m2) URINE=RED IF EXTRAVASATION OCCURS= cool/ice + Totect Idamycin Cardiotoxic (cardiomyopathy) Bleomycin AVOID oxygen supplementation Methotrexate Leukovorin decreases cytotoxicity Pemetrexed Vitamin B12 & folic acid supplements to decrease toxicity Fludarabine Immunosuppression Thioguanine Bone Marrow Suppression Stomatitis/Mucositis 5-FU *Stomati...

nadir lowest blood cell count after chemotherapy, 10-14 days but varies with individual agents cisplatin ototoxic --> report tinnitus nephrotoxic --> monitor BUN and creatinine depletes K and Mg --> replacement prior/after cytoxan hemorrhagic cystitis >3000ml/day fluid intake unless contraindicated void q2-4 hours day, q4 hours night can also cause sinus drainage, slow infusion oxaliplatin hang with D5W cold sensitivity (Ixnay on the ice, okay?) ...