Sh2 and 3 domains Study guides, Revision notes & Summaries

CPPS FINAL EXAM Practice Questions WITH CORRECT ANSWERS Graded A+ | 2023/2024. What is the importance of RBD in Raf activation? - Correct Answer-It is the N-terminal regulatory domain of the Raf protein. The RBD needs to interact with RasGTP to enable activaiton of Raf. Interaction of RBD with RasGTP at the membrane destabilizes Raf interaction with 14-3-3. This allows for PP2A to dephosphorylate Raf phosphoserines (the locks on the inactive state). What is RBD? - Correct Answer-Ras Binding...

Quiz questions based on Lecture 13 (Signaling-1). 1. What is always present in a signaling pathway? A. Signal that originates outside a cell B. Signal that remains outside the responding cell during signaling C. Cell-surface receptor D. A and B are correct 2. Adrenaline is a signal used in the fight-or flight response. Adrenaline signaling is A. Endocrine B. Paracrine C. Autocrine D. Contact-dependent 3. One signal can have different effects on the same cell; for example, it can alter...

CPPS 325 FINAL EXAM QUESTIONS AND ANSWERS 2023 What are the 5 well-known enzyme-linked cell surface receptors? 1. Receptor Guanylyl Cyclase: produces cGMP 2. RTK: phosphorylate tyrosine residues leading to association of signalling molecules and cascade 3. TK Associated Receptors: associate with proteins having TK activity 4. Receptor Tyrosine Phosphates: Removes phosphate on tyrosine residues 5. Receptor Serine/Threonine Kinases: phosphorylate specific Serine/Threonine residues on IC sign...

CPPS 325 FINAL EXAM question and answers 2023What are the 5 well-known enzyme-linked cell surface receptors? - correct answer 1. Receptor Guanylyl Cyclase: produces cGMP 2. RTK: phosphorylate tyrosine residues leading to association of signalling molecules and cascade 3. TK Associated Receptors: associate with proteins having TK activity 4. Receptor Tyrosine Phosphates: Removes phosphate on tyrosine residues 5. Receptor Serine/Threonine Kinases: phosphorylate specific Serine/Threonine resi...

The point of these lectures was: - become familiar with the concept of modular protein - Learn about their biological significance •Learn about the significance of protein modularity in protein interactions and regulatio