Intracellular signalling Study guides, Revision notes & Summaries

Charles-Edouard Brown-Sequard - Answer Injected himself with ground-up animal testicles led to development of modern hormone therapy. Largely placebo Basic Principle of a Cell Signalling Pathway - Answer Stimuli -> Receptors -> Transducers -> Amplifiers -> Messengers -> Sensors and Effectors -> Cellular Responses (Fertilization, Proliferation, Differentiation, Secretion, Contraction, Metabolism, Membrane Excitability, Learning and Memory). Ligand Receptor Interaction - An...

UNC Biol 205 Exam 2 Questions With Verified Answers when cells respond to an extracellular signal, they most often convert the information carried by this molecule from one form to another. What is this process called? - answersignal transduction When does signal transduction begin? - answerwhen the receptor on a target cell recieves and incoming extracellular signal and then produces intracellular signaling molecules that alter cell behavior extracellular signal molecules, released loca...

UNC Biol 205 Exam 2 Questions With Verified Answers when cells respond to an extracellular signal, they most often convert the information carried by this molecule from one form to another. What is this process called? - answersignal transduction When does signal transduction begin? - answerwhen the receptor on a target cell recieves and incoming extracellular signal and then produces intracellular signaling molecules that alter cell behavior extracellular signal molecules, released loca...

when cells respond to an extracellular signal, they most often convert the information carried by this molecule from one form to another. What is this process called? - Answer-signal transduction When does signal transduction begin? - Answer-when the receptor on a target cell recieves and incoming extracellular signal and then produces intracellular signaling molecules that alter cell behavior extracellular signal molecules, released locally example: inflammation regulation at site of infe...

Why is cell signalling complex? - -not isolated pathways -all work together What is intracellular signalling? - a set of linked biochemical events that connect a specific biological stimulus with a specific cellular response What sorts of cell behaviours are controlled with communication between cells or environment? - their ability to... -survive -divide -migrate -differentiate -die

Signal Transduction - The process of converting signals from one form to another. In cells: Extracellular signaling molecule --> receptor --> intracellular signaling molecules --> effector proteins Extracellular Signaling Molecules - this type of signaling molecule comes from outside of the cell, and can come in many different forms Receptor - this is a generic term for what binds a ligand Intracellular signaling molecule - as a result of a receptor being bound, this is released in...

What is cell signalling? correct answer: "Transduction of message(s) from one cell to another cell resulting in altered behaviour of target cell" What are the basic requirements of cell signalling? correct answer: 1. Signalling cell. 2. Extracellular ligand (signalling molecule). 3. Target (responding) cell. 4. Receptor (on plasma membrane or intracellular) Illustrate a general schematic of cell signaling correct answer: What are the 3 types of signalling? correct answer: 1. Endo...

UNC Biol 205 Exam 2 Questions With Verified Answers when cells respond to an extracellular signal, they most often convert the information carried by this molecule from one form to another. What is this process called? - answersignal transduction When does signal transduction begin? - answerwhen the receptor on a target cell recieves and incoming extracellular signal and then produces intracellular signaling molecules that alter cell behavior extracellular signal molecules, released loca...

How targeted therapy and chemo differ -targeted therapies act on specific molecular targets on or within the cells that are associated with cancer, whereas standard chemo act on all rapidly dividing cells-chemo has more SEs-targeted therapy ae chosen and designed to interact with their target on or within the cells, whereas chemo were IDed becaused they kill cells-targeted therapies are often cytostatic (they block tumor cell proliferation) whereas chemo agents are cytotoxic (kill tumor cells) ...

FOPC 1 Exam #2 complete with correct answers 100% Calcium - answers muscle contraction, nerve funciton, vascular function, coagulation, intracellular signalling, hormone secretion, bone Vitamin D - answers required for absorption of 75% of dietary calcium, need 10-15% of UV exposure DEXA scan criteria - answers osteoporosis = -2.5 and higher (more neg) osteopenia = -1 - -2.4 (low bone mineral density) Risk Factors for Osteoporosis - answers postmenopause, ...