Km and vmax Study guides, Revision notes & Summaries

Pre-PCOA Exam Latest Update (2022/2023) Already Passed Methods to enhance a drug's solubility in a solvent 1. Heat 2. Co-solvents increase the solubility of hydrophobic molecules by reducing the dielectric constant of the solvent 3. pH-Assisted solubility processes of drug elimination from the body liver, kidney and bile primary, secondary, tertiary and quaternary structures of proteins a. 1° primary - amino acid sequence of the polypeptide (Controls levels 2, 3, and 4) b. 2° secondary - l...

tbr- enzyme kinetics exam questions & answers 2024 allosteric enzyme - ANSWER-often have multiple inhibitor or activator binding sites to change conformation, switching between active and inactive shapes allosteric curve - ANSWER-sigmoidal shape ex. hemoglobin = allosteric protein transition state analogs - ANSWER-synthesized compounds that mimic the form of the transition state of a substrate molecule and binds to the enzyme to inhibit catalysis rxn transition state vs intermedi...

UNE Biochem 1005 Final Study Set Questions With Complete Solutions. Which of the following best describes the structure of heme? -a nicotinamide structure that is readily oxidized -a negatively charged phosphate group -a planar porphyrin ring that binds iron -an n-link glycosylation A planar porphyrin ring that binds iron Covalent catalysis is used by many enzymes to cleave peptide bonds. Which of the following amino acids would not facilitate this type of catalysis? -valine -cysteine...

UNIT 1 UNE CHEM 1005 EXAM QUESTIONS AND ANSWERS Hemoglobin binds oxygen with a greater affinity in the: R state Hemoglobin bound to heme is termed a holoprotein. The heme or porphoryin ring is required for oxygen binding and it is termed a: prosthetic group Alpha helices and beta sheets are primarily stabilized by: H bonding Ligases are a class of enzymes characterized by their ability to: synthesize bonds between carbon atoms and an additional atom that is involved in the cleavage of ...

what percentage of water is in the body? 60% Relationship between protons and acids & bases Acids donate proton. Bases accept proton Strong Acids Vs Weak Acids Strong acids fully dissociate (100%) and weak acids partially dissociate properties of water dipole dipole polar H bonding dissolves electrolytes ( CL /Na) Small Kd- doesn't dissociate alot kw ion product 10^-14 pH -log[H+] biological PH 7.4 types of buffers phosphates, bicarbo...

BIOCHEM 3560 Quiz 2 | Practice Questions With Answers Latest 2023/2024. The Michaelis-Menten equation does not: Describe enzyme kinetics in terms of two independent constants Have the enzyme velocity approach Vmax asymptotically as substrate concentration increases Apply to allosteric enzymes Have a hyperbolic form Show half maximal enzyme velocity when substrate concentration is equal to Km Question 2 From the reaction rate plot, which metabolites acts as an allosteric modulators? NH3...

BIOCHEMISTRY ACS EXAM QUESTIONS WITH 100% CORRECT ANSWERS Unfolds proteins and gives them uniform negative charge. - answerSDS Reacts with the N-terminus of the protein to produce a 2,4-dinitrophenol derivative that labels the first residue. Can repeat hydrolysis to determine sequential amino acids - answerFDNB Reduces disulfide bonds. - answerDTT Adds carboxymethyl group on free -SH groups. Blocks disulfide bonding. - answerIodoacetate Bonds between two -SH groups that form between 2°...

171 Biochemistry Exam 1 Questions with correct answers 2023/ Biochemistry Exam 1 Questions with correct answers 2023/2024 Myoglobin >>What protein is used for storage? Myoglobin Hemoglobin Collagen Transferrin It's a covalent interaction >>What is NOT TRUE of antibodies with respect to protection? It is a covalent interaction It's a noncovalent interaction; hydrogen bonding Aspartic acid pKa=3.9 >>What is the amino acid that would dissociate a proton and ma...

1. Which of the following does not contribute to the regulation of enzymatic activity? A) Protein phosphorylation B) Allosteric regulation C) Protein stability D) mRNA stability E) DNA stability - E 2. For an enzyme to effectively change its activity in response to a change in substrate concentration, it is most favorable for: A) Km to be less than cellular substrate concentrations. B) Km to be equal to cellular substrate concentrations. C) Km to be greater than cellular substrate conc...

UNIT 1 UNE CHEM 1005 EXAM QUESTIONS AND ANSWERS Hemoglobin binds oxygen with a greater affinity in the: R state Hemoglobin bound to heme is termed a holoprotein. The heme or porphoryin ring is required for oxygen binding and it is termed a: prosthetic group Alpha helices and beta sheets are primarily stabilized by: H bonding Ligases are a class of enzymes characterized by their ability to: synthesize bonds between carbon atoms and an additional atom that is involved in the cleavage of ...