E3 ligase Study guides, Revision notes & Summaries

primary epigenetic marks = sequence specific - intrinsic DNA sequence - sequence-specific TFs - noncoding RNA secondary epigenetic marks = sequence independent - readers of DNA methylation - noncoding RNA methylation in bacteria - methylation A or C to identify & degrade invading DNA & track mismatch methylation in bacteria functions - timing of DNA replication - partitioning nascent chromosomes to daughter cells - repair of DNA - timing of transposition & conjug...

A 2 year old girl who is exposed to the sun has progressive development of dryness of the skin, excessive freckling, and keratoses. Skin fibroblasts cultured from this child are most likely to be defective in which of the following? Nuclear excision repair of pyrimidine dimers a 65 year old man has a radical prostacetomy and lymph node dissection for adenocarcinoma of the prostate. which of the following features is involved in the grading of this neoplasm Tumor size A man with a fair ...

BIOM 500 QUIZ 3 PRACTICE NEW UPDATED EXAM QUESTIONS AND ANSWERS 1. Terminally differentiated cells go into the quiscent stage of the cell cycle also described as G0 Phase G1 Phase G2 Phase S phase 2. Cancer cells actively duplicate their genetic material in the stage of the cell cycle called; S Phase M Phase G1 Phase G2 Phase 3. Cyclin-dependent kinase 6 exerts its cell cycle progression effects by acting on these substrates except; Rb SMAD2 P130 p53 4. An inhibition of...

What are the 3 different branches of life? - answer-1) Bacteria 2) Archaea 3) Eukaryotes What are the similarities between bacteria, archaea, and eukaryotes? - answer-1) Basic Biochemistry 2) Genetic code 3) Membrane ATPase 4) Ribosome What are the similarities between Bacteria and Archaea? - answer-1) No nucleus or organelles 2) Coupled transcription and translation What are the similarities between Archaea and Eukaryotes? - answer-Similar machinery for handling information (e.g...

1. Which of the following is/are TRUE for RNA compared to DNA?A) RNA has ribose sugar in its nucleotides, rather than the deoxyribose found in DNA.B) RNA is usually single stranded and can make more complex three-dimensional molecular shapes than double-stranded DNA.C) RNA contain the bases A, G, C, and U, whereas DNA contain the bases A, G, C, and T.D) RNA can catalyse biological reactions, but DNA cannot.E) All of the answer options are correct. - ANSWER E 2. Before the completion of the hu...

In-depth lecture notes on the ubiquitin cycle including the principal enzymes (E1, E2, E3), different types of ubiquitin chains and their functions (signalling, proteosomal degradation, trafficking), and crosstalk between ubiquitination and phosphorylation in the NFkB pathway. The NFkB pathway is also discussed in detail (proteins/posttranslational modifications involved, activation of the pathway, negative feedback loop which inhibits the pathway, and a relatively new model of the pathway invol...