Claisen reaction Study guides, Revision notes & Summaries

--NO2 + Sn/HCl - Correct Answers>Clemmenson Reduction --NH2 1,2-addition conj double bonds + RMgX or LiAlH4 - Correct Answers>Nucleophiles attack the carbonyl directly. Strong nucleophiles: Gringards, NaBH4, LiAlH4 1. (2) esters CH3--C=O--OEt + NaOR, EtOH 2. H3O+ ketone + (ester) CH3--C=O--OEt + -OR + H3O+ --> - Correct Answers>Claisen Condensation enolate ion of one ester acts as nucleophile attacking another ester 1. NaOR, EtOH 2. H3O+ Anhydride for mixed 1. BH3/TH...

CHEM 309 Organic Chemistry II homework 10 With Completed Solutions- Boise State University Acid chlorides are the most reactive carboxylic acid derivatives. Provide curved arrows to complete t he following reaction mechanism for attack of a typical neutral nucleophile to an acid chloride. Remember the rules for drawing curved arrows: begin each arrow at a bond or lone pair (draw them in) and end each arrow at an atom or bond. lb) When neutral nucleophiles react with acid chlorides or anhydrides-...

This is my second part of Chapter 17 and these notes cover the complex aldol reaction as well as some of its variants. This also goes over alpha-beta unsaturated aldehydes and ketones and their specific types of addition reactions.

This document covers the first half of Chapter 17: Reactions at the alpha-Carbon of Carbonyl Compounds, Enols and Enolates, and alpha-beta Unsaturated Carbonyl Compounds. These notes were taken from lecture and start from a description of the reactivity of such compounds and certain reaction that coincide with them.

Answer Key on last page Chapter 27: Pericyclic Reactions 1. Which of the following statements about pericyclic reactions is true? A) Pericyclic reactions occur by way of ionic intermediates. B) Pe ricyclic reactions occur by way of radical intermediates. C) Pericyclic reactions involve multiple steps. D) Reactive intermediates are not formed in pericyclic reactions. 2. Which of the following statements about pericyclic reactions is true? A) In pericyclic reactions, bonds are broken and formed in...

CHEM 2420 ---Organic Chemistry II Fall 2015 Mid-Exam No. 2: Chapter 17-18 (Form A) Name: ÿ'ÿ,ÿt ÿ-,4 Instructions: A) Please print your name on the line above. B) Make sure you have 12 pages. C) Good luck! Question Score Multiple choice /80 Free response Bonus Total /20 /5 /105 1 IP aÿ.,o e Section 1. Multiple Choice (80 points) Bubble the choice that best completes each phrase and/or answers the question on the Scantron sheet provided. Answers written in this section of...

Application of carbonyl group chemistry in organic synthesis: The material covered in this section includes (i) a-hydrogen acidity, (ii) acid and base promoted keto-enol tautomerism, (iii) a-enolate chemistry, including alkylation (iv) named reactions including Michael reaction, Aldol addition, Aldol condensation, Claisen condensation (v) ring-forming reactions including Dieckman condensation and Robinson annulations

An introduction to the reactions of malonates and 1,3 dicarbonyls including Claisen reaction, alkylation, ring synthesis. A look at enones, how to create them and their reactivity of 1,2 and 1,4 addition attack, the use of organometallics with enones. Then notes on the formation and addition of 1,5 dicarbonyls including Robinson's annelation. An introduction to the disconnection approach for retrosynthesis. 1,4 dicarbonyls and their reactions are introduced. 1,2 Dicarbonyls/Difunctionals reacti...

Most notes are types and structure drawn with chemdraw, some mechanism, and quite cheat sheet are shown in neat handwriting produced on ipad. Most reactions show detailed step-wise mechanism (with electron transfer arrows) Material covered are as shown below Carbonyl rearrangements: Schmidt, Beckmann, Curtius, Wolff Enols and Enolates: ketone deuteration, alpha-halogenations, alpha-alkylations, enamine alkylations, decarboxylation Aldol Reaction: general, condensation, Cross Aldol condensation, ...