Clinical pathology (LSC-30009)

Prenatal is defined and the advancement of prenatal testing. The essay evaluates the current and novel techniques of prenatal testing. PAPP-A, B-hCG, the accuracy of NIPT, is described. Amniocentesis and chronic villus sampling diagnosis are discussed. Followed by a discussion of molecular advances such as FISH, MPLA. Subsequently, newer technology evaluating genomic microarray analysis is discussed. References are given

Critically discuss molecular advances in prenatal testing. How have these advances impacted upon patient care? Haematology is defined and background information is provided on the haemopoietic hierarchy and stem cell differentiation and current stem cell disorders. Followed by how morphologic assessment is carried out - methods and stains for myeloid and leukemic lymphoblasts. Then, cytogenetic analysis is discussed. PCR and miRNAs techniques are discussed. References provided

Haematology is defined and background information is provided on the haemopoietic hierarchy and stem cell differentiation and current stem cell disorders. Followed by how morphologic assessment is carried out - methods and stains for myeloid and leukemic lymphoblasts. Then, cytogenetic analysis is discussed. PCR and miRNAs techniques are discussed. References provided

Critically discuss the current and potential use of haematology in thescreening and diagnosis of disease. Illustrate your answer with relevant examples Haematology is defined and background information is provided on the haemopoietic hierarchy and stem cell differentiation and current stem cell disorders. Followed by how morphologic assessment is carried out - methods and stains for myeloid and leukemic lymphoblasts. Then, cytogenetic analysis is discussed...