Gwas Samenvattingen, Aantekeningen en Examens

I worked in a genetics lab at the University of Chicago for about a year during peak covid. I spent a lot of time there in my apartment, reading papers, watching videos, and taking notes. I thought others might find them interesting / useful

Dit document bevat de aantekeningen van lecture 8. De lectures zijn engels en Nederlandstalig aangezien de colleges in het engels worden gegeven.

Dit is het vijfde college. De notes zijn deels engels en deels Nederlands ivm met engelstalige college.

Dit is het achtste college. De notes zijn deels engels en deels Nederlands ivm met engelstalige college.

Dit is een uitgebreide samenvatting van het hoorcollege over de presynaptische neuron door Ron Habets. Onderwerpen die aan bod komen zijn: SNPs, CNVs, GWAS, epilepsie, STXBP1, Mucn18, DNM1, SNAP-25, SYN1, tonic-clonic, abscence, petit mal, focal seizure, neurotransmitter, kindling model, actieve zone, voltage clamp, current clamp, synchronous-evoked release, asynchronous-evoked release, mini, calcium, vesicle cyclus, bruchpilot, readily releasable pool, recycling pool, reserve pool, FM1-43 dye, ...

All the lectures given in the study year of 2018-2019 of the course Ecogenomics are summarized. The summary is written by hand and put together in a PDF. Lectures are about strigolactones, DNA structure, QTL, gene expression, metabolomics, GWAS, transcription factors, epigenetics and genomics & breeding

Summary of the course neurogenomics of speech, language and reading disorders which is given in the master of medical biology

Mapping Mendelian disease lecture notes.

Dit is een samenvatting van de colleges van Experimental Immunology deel 2 en bevat: 1. Epigenetic regulation of macrophages (MS) 2. Mass cytometry 3. Intravital microscopy 4. SNP in GWAS 5. GWAS and mouse models for IBD 6. Gene expression 7. Methods to inhibit or induce gene expression

The advent of GWAS has been driven by the relevant genome projects paralleled with rapid technological advancements. The GWAS provide a framework and methodology to further understand the genetic variants involved in common and complex diseases, such as diabetes type 2. Prior to GWAS, novel approaches such as linkage analysis was used to determine SNP’s. There has been a degree of criticism to the relevance of the GWAS in relation to the money invested in it. A major principle for the basis of...