Gpcrs Samenvattingen, Aantekeningen en Examens

Lipinski's rule of 5 - ANSWER-- Poor absorption or permeation are more likely when: 1. mass greater than 500 Da 2. highly lipophilic - logP > 5 3. more than 5 hydrogen bond donors 4. more than 10 hydrogen bond acceptors Partition coefficient - ANSWER-p = C(octanol)/C(water) - ratio of the equilibrium concentrations of dissolved substance in a two-phase system containing two largely immiscible solvents (water & octanol) - Log10(P) Improved Lipinski Parameters - ANSWER-1. Partition...

MPP Exam Questions With 100% Correct Answers Understand the basic effects of nAChR ganglionic antagonists (which are no longer used) - Answer-Specifically block NAChR in the ganglia Hexamethonium (No CNS) Mecamylamine (Yes CNS) Effects are the opposite of the predominant tone (either symp or para sym effects) Effects of nAChR ganglionic antagonists in the arterioles, heart and GI -Answer-always opposite of predominant tone Arterioles: hypotention/ postural hypotention Heart: tachycardia...

Sedative-hypnotic drug Correct Answer: causes sedation & anxiolysis or encourages sleep; all drugs in this class cause dose-dep CNS depr EXC for buspirone (non-sedating anxiolytic), propranolol (perf anxiety) Diagnoses treated with sedative-hypnotics Correct Answer: - Insomnia = diff falling asleep (sleep onset), staying asleep (sleep maint), waking up too early/not able go back to sleep - Anxiety = ac anx, chron anx (persis worrying out of prop, overthinking/expecting worst case, aff dai...

when cells respond to an extracellular signal, they most often convert the information carried by this molecule from one form to another. What is this process called? - Answer-signal transduction When does signal transduction begin? - Answer-when the receptor on a target cell recieves and incoming extracellular signal and then produces intracellular signaling molecules that alter cell behavior extracellular signal molecules, released locally example: inflammation regulation at site of infe...

Duquesne University BIOL-212 Exam 4 Quiz Questions Answer Key. 1) Which THREE of the answer choices below commonly act as molecular switches in signaling pathways? a) Kinases b) Transcription factors c) Phosphatases d) GTP-binding proteins e) Calcium 2) Uh oh - you met someone new and were scrolling through their social media posts from 5 years ago and accidentally clicked "like" - and now you are panicking that they will know you were looking! Your heart begins to race, thanks to th...

This is a clear and concise summary about the BBS2042 course, which has all the cases and lectures integrated within the summary so that all the information you need to know is present.

NSCI 175 Final Exam Review. Questions with complete Answers 2023 Explain Why Progress in science is often slow -Because experiments take time and the process of observation, replication, interpretation, and verification is exhaustive. It also takes time to get published and for the new information to become widespread. Explain the Reductionist Approach: - How is the Approach? Is the process of breaking down the enormous problem of understanding how the brain works into smaller pieces ...

MPP Exam Questions With 100% Correct Answers Understand the basic effects of nAChR ganglionic antagonists (which are no longer used) - Answer-Specifically block NAChR in the ganglia Hexamethonium (No CNS) Mecamylamine (Yes CNS) Effects are the opposite of the predominant tone (either symp or para sym effects) Effects of nAChR ganglionic antagonists in the arterioles, heart and GI -Answer-always opposite of predominant tone Arterioles: hypotention/ postural hypotention Heart: tachycardia...

1 BIOCHEMISTRY EXAM 2 | QUESTIONS & ANSWERS (VERIFIED) | LATEST UPDATE | GRADED A+ Covalent Catalysis Correct Answer: Active site contains a reactive group (Nucleophile) General Acid-Base Catalysis Correct Answer: Molecule (other than Water) acts as a proton donor or acceptor Metal Ion Catalysis Correct Answer: Metal ion serves as an electrophilic catalyst and stabilizes reaction intermediate Temperature Correct Answer: As temperature rises, reaction rate increases; loss of activ...

NSCI 175 Final Exam Learning Objectives Questions with complete Answers 2023 Explain the reductionist approach breaking down how the brain works Compare different levels of analysis in neuroscience research Molecular: allows neurons to communicate, sentries that control what material enters/leaves neurons, conductors that orchestrate neuron growth, archivists of past experiences Cellular: focuses on how all these molecules work together to give neurons their special properties S...