Clinical Pharmacology Samenvattingen, Aantekeningen en Examens

most drugs produce their effects by...binding to protein molecules drug binding often leads to...conformational change in the protein Four primary drug targets are:1. ion channels 2. enzymes 3. carrier molecules 4. receptors *exception DNA on which a number of anti tumour and antimicrobial drugs act The only exception to proteins as target sites is...DNA on which a number of anti tumour and anti microbial drugs act

Drug Any chemical that can affect living processes Pharmacology Study of drugs and their interactions with living systems Clinical pharmacology Study of drugs in humans Pharmacotherapeutics Use of drugs to diagnose,prevent, or treat disease or prevent pregnancy Properties of an Ideal Drug Effectiveness Safety Selectivity Reversible action Predictability Ease of administration Freedom from drug interactions

What does pharmacokinetics mean? what the BODY does to drug What does pharmacodynamics mean? what the DRUG does to body Name the 4 factors of pharmacokinetics (MADE) - Metabolism - Absorption - Distribution - Excretion what does bioavailability mean? fraction of drug that reaches systemic circulation Oral route for drug - variable bioavailability - drugs absorbed more rapidly from small intestine than from the stomach Parenteral administration drugs are given by injection into the skin,...

TESTBANK TO INTRODUCTION TO CLINICAL PHARMACOLOGY 10TH EDITION,VISOVSKY (Chapter 1-20) FULLY COVERED.

Introduction to Clinical Pharmacology 9TH EDITION

Drug Any chemical that can affect living processes Pharmacology Study of drugs and their interactions with living systems Clinical pharmacology Study of drugs in humans Pharmacotherapeutics Use of drugs to diagnose,prevent, or treat disease or prevent pregnancy Properties of an Ideal Drug Effectiveness Safety Selectivity Reversible action Predictability Ease of administration Freedom from drug interactions

Pharmokinetics what the body does to the drug (absorption, distribution, metabolism, excretion) Pharmacodynamics what the drug does to the body; mechanism of action Why do we administer drugs intramuscularly? For drugs with poor absorption (or no IV line) What routes bypasses the liver(portal circulation) initially? Rectal and sublingual What are the 4 steps of a Pharmacokinetic Study? Step 1 : dose animal or human Step 2: collect samples(blood,urine,stool,bile) at various timepoints S...

most drugs produce their effects by...binding to protein molecules drug binding often leads to...conformational change in the protein Four primary drug targets are:1. ion channels 2. enzymes 3. carrier molecules 4. receptors *exception DNA on which a number of anti tumour and antimicrobial drugs act

What does pharmacokinetics mean? what the BODY does to drug What does pharmacodynamics mean? what the DRUG does to body Name the 4 factors of pharmacokinetics (MADE) - Metabolism - Absorption - Distribution - Excretion what does bioavailability mean? fraction of drug that reaches systemic circulation Oral route for drug - variable bioavailability - drugs absorbed more rapidly from small intestine than from the stomach

Test bank for Introduction to Clinical Pharmacology 9th edition by Constance G Visovsky||Latest update 2024||All Chapters Fully Covered