Saturation kinetics Samenvattingen, Aantekeningen en Examens

Homeostasis 1. Which one of the following is an example of a homeostatically controlled variable? (A)Heart rate (B) Body temperature (C) Hypothalamus (D)Thermoreceptors (E) Autonomic nervous system Answer: B. Only choice A and B are variable, and the body doesn’t maintain heart rate homeostatically. Feedback System 2. Which of the following is an example of negative feedback? (A)Increasing blood glucose level in hyperglycemia (B) Decreasing blood glucose level in hypoglycemia (C)...

The driving force for passive absorption of a drug is the: a. specific carrier proteins and shows saturation kinetics b. concentration gradient across a membrane separating body compartment c. both d. none - b. concentration gradient across a membrane separating body compartment Physical factors influencing absorption: a. total surface area available for absorption b. contact time at the absorption surface c. blood flow to the absorption site d. all e. none - d. all Clinical effective...

Pre-PCOA Exam Latest Update (2022/2023) Already Passed Methods to enhance a drug's solubility in a solvent 1. Heat 2. Co-solvents increase the solubility of hydrophobic molecules by reducing the dielectric constant of the solvent 3. pH-Assisted solubility processes of drug elimination from the body liver, kidney and bile primary, secondary, tertiary and quaternary structures of proteins a. 1° primary - amino acid sequence of the polypeptide (Controls levels 2, 3, and 4) b. 2° secondary - l...

The driving force for passive absorption of a drug is the: a. specific carrier proteins and shows saturation kinetics b. concentration gradient across a membrane separating body compartment c. both d. none - b. concentration gradient across a membrane separating body compartment Physical factors influencing absorption: a. total surface area available for absorption b. contact time at the absorption surface c. blood flow to the absorption site d. all e. none - d. all Clinical effective...

The driving force for passive absorption of a drug is the: a. specific carrier proteins and shows saturation kinetics b. concentration gradient across a membrane separating body compartment c. both d. none - b. concentration gradient across a membrane separating body compartment Physical factors influencing absorption: a. total surface area available for absorption b. contact time at the absorption surface c. blood flow to the absorption site d. all e. none - d. all Clinical effective...

Enzyme Kinetics and Km - correct answer-The reaction catalysed by an enzyme uses exactly the same reactants and produces exactly the same products as the uncatalysed reaction. Like other catalysts, enzymes do not alter the position of equilibrium between substrates and products. Enzyme-catalysed reactions display saturation kinetics: For a given enzyme concentration and for relatively low substrate concentrations, the reaction rate increases linearly with substrate concentration; the enzym...

Passive Diffusion - Answer High conc. -> low majority of drugs work this way does not involve carrier, is not saturable, and shows a low structural specificity Facilitated Diffusion - Answer involves carrier proteins High conc -> low no energy required, an be saturated, may be inhibited by compounds that compete for the carrier Active Transport - Answer Shows saturation kinetics for the carrier drugs closely resemble naturally occurring metabolites that are actively transp...

Passive Diffusion - Answer High conc. -> low majority of drugs work this way does not involve carrier, is not saturable, and shows a low structural specificity Facilitated Diffusion - Answer involves carrier proteins High conc -> low no energy required, an be saturated, may be inhibited by compounds that compete for the carrier Active Transport - Answer Shows saturation kinetics for the carrier drugs closely resemble naturally occurring metabolites that are actively transp...

GMS 6504 MODULE 1-3 Exam 1 Questions and Answers 100% Pass What are System Independent Parameters? - Answer- Affinity Efficacy What are the parts of a system that are identified as System Dependent Parameters? - Answer- Number of receptors Cellular machinery Presence of other drugs - Competitive - Noncompetitive Affinity is - Answer- Thermokinetic propensity of drug to bind to receptor Based largely on ΔG Efficacy is - Answer- Magnitude of change of receptor shape/function upon drug...

Biochemistry Test 1 Questions and Answers Graded A+ biochemistry a discipline in biochemistry; is the description of molecules in biology/chemistry of proteins molecular biology a discipline in biochemistry; the manipulation of DNA, genetics cell biology a discipline in biochemistry; larger scale, functions and mechanisms within a cell/cell energetics cellulose a natural polymer; found in plants for storage glycogen a natural polymer; found in animals for storage protein a natural polymer; ...