Ligand binding Samenvattingen, Aantekeningen en Examens

Charles-Edouard Brown-Sequard - Answer Injected himself with ground-up animal testicles led to development of modern hormone therapy. Largely placebo Basic Principle of a Cell Signalling Pathway - Answer Stimuli -> Receptors -> Transducers -> Amplifiers -> Messengers -> Sensors and Effectors -> Cellular Responses (Fertilization, Proliferation, Differentiation, Secretion, Contraction, Metabolism, Membrane Excitability, Learning and Memory). Ligand Receptor Interaction - An...

competitive antagonist correct answer: an agonist that "competes" for the same binding site as another substance only blocks endogenous ligand, cannot activate receptor reversible competition Competitive antagonists cause a _____ shift in the drug response curve correct answer: rightward T/F: Competitive antagonism can be surmounted by adding more agonist correct answer: True! With enough agonist, you can flood the receptors so that the angonist out competes the competitive antagon...

4 Types of receptors CORRECT ANSWER -G-protein coupled receptor: adrenergic, serotonin, dopamine, acetylcholine, dopamine,histamine, opiates -Ligand Gated Ion Channel: Acetylcholine (nicotinic) NMDA, GABA competitive/noncompetitive /allosteric (NAM, PAM (benzos), allosteric modulator) -Tyrosine Kinase Receptor: Dimers, Jac/stat, example is insulin -Steroid Hormone receptors: steroids are transported in blood by corticosteroid binding protein to CYTOSOL. Activated by Estrogen, progeste...

BIOC 3560 Midterm Exam Questions With Answers Latest 2023/2024 (Graded 100%). Select the statement that accurately describes an O2-binding curve of a globin. (A) The heme-O2 binding curve is a sigmoidal curve. (B) Hemoglobin and myoglobin have reciprocal pO2-binding curves. (C) Hemoglobin has a sigmoidal O2-binding curve. *** (D) Myoglobin has a sigmoidal O2-binding curve. (E) All of the above. 2. Which statement is false with respect to enzyme phosphorylation? (A) The modification is irr...

What is the primary storage form of fatty acids? Correct Answer-D) triglycerides A pore that simultaneously transports two different molecules in the same direction is called a(n) Correct Answer-B) symporter Which of the following may undergo transverse diffusion within the lipid bilayer? Correct Answer-A) membrane lipids In which type of reversible inhibition does binding substrate facilitate binding of the inhibitor? Correct Answer-C) uncompetitive Which of the following is a ligan...

drug action correct answers molecular changes that occur as a result of a drug or neurotransmitter binding to a receptor drug actions in the body drug effect correct answers widespread physiological or psychological changes as a result of molecular changes overall effect binding affinity correct answers how strongly a drug binds to the receptor efficacy correct answers how likely a drug is to exert a biological response once bound to the receptor pharmacodynamics correct answers fu...

Which of the following is not involved in the specificity of signal transduction? A) Interactions between receptor and signal molecules B) Location of receptor molecules C) Structure of receptor molecules D) Structure of signal molecules E) Transmembrane transport of signal molecules by receptor molecules - Transmembrane transport of signal molecules by receptor molecules Which of the following is not a feature of signal transduction? A) Integration of multiple pathways toward the same d...

Draw and label the myoglobin binding curve. - Answer A hyperbolic curve -> Y is the fraction of ligand-binding sites -> Kd is the dissociation constant (x value of y = 0.5) -> A high Kd means more dissociation. -> P50 is the partial pressure when oxygen (or something) occupies 50% of the binding sites. What does the hyperbolic shape tell us about the sensitivity of myoglobin to changes in ligand concentration? - Answer Myoglobin is very sensitive to ligand and will take up a lo...

ABSITE EXAM REAL QUESTIONS AND CORRECT ANSWERS COMPLETE SET | PASSED 1. The vagus nerve mediates what in the setting of systemic inflammation? Enhanced gut motility 2. What type of hormones are cytokines? polypeptide 3. Function of heat shock proteins Binding of autologous proteins to improve ligand binding 4. Omega-3 fatty acids have what affect on the inflammatory response? Decrease 5. What is a known affect of TNF? Expression of eicosanoids (like thromboxane) 6. What...

Biol 1201 Final – Gregg Latest Update Graded A+ local signaling animal cells may communicate by direct contact, or cell-cell recognition (paracrine and synaptic signaling) cell junctions Animal and plant cells; directly connect the cytoplasm of adjacent cells paracrine signaling the target cells lie near the secreting cells synaptic signaling a nerve cell releases neurotransmitter molecules into a synapse, stimulating the target cell endocrine (hormonal) signaling Specializ...