Signalling pathways Samenvattingen, Aantekeningen en Examens

What are the 5 well-known enzyme-linked cell surface receptors? 1. Receptor Guanylyl Cyclase: produces cGMP 2. RTK: phosphorylate tyrosine residues leading to association of signalling molecules and cascade 3. TK Associated Receptors: associate with proteins having TK activity 4. Receptor Tyrosine Phosphates: Removes phosphate on tyrosine residues 5. Receptor Serine/Threonine Kinases: phosphorylate specific Serine/Threonine residues on IC signalling molecules How are RTK and TK Associat...

What are the 5 well-known enzyme-linked cell surface receptors? 1. Receptor Guanylyl Cyclase: produces cGMP 2. RTK: phosphorylate tyrosine residues leading to association of signalling molecules and cascade 3. TK Associated Receptors: associate with proteins having TK activity 4. Receptor Tyrosine Phosphates: Removes phosphate on tyrosine residues 5. Receptor Serine/Threonine Kinases: phosphorylate specific Serine/Threonine residues on IC signalling molecules How are RTK and TK Assoc...

CPPS 325 FINAL EXAM Questions and Answers 2023 What are the 5 well-known enzyme-linked cell surface receptors? 1. Receptor Guanylyl Cyclase: produces cGMP 2. RTK: phosphorylate tyrosine residues leading to association of signalling molecules and cascade 3. TK Associated Receptors: associate with proteins having TK activity 4. Receptor Tyrosine Phosphates: Removes phosphate on tyrosine residues 5. Receptor Serine/Threonine Kinases: phosphorylate specific Serine/Threonine residues on IC sign...

Why is cell signalling complex? - -not isolated pathways -all work together What is intracellular signalling? - a set of linked biochemical events that connect a specific biological stimulus with a specific cellular response What sorts of cell behaviours are controlled with communication between cells or environment? - their ability to... -survive -divide -migrate -differentiate -die

CPPS 325 FINAL EXAM Questions and answers rated A+ 2023What are the 5 well-known enzyme-linked cell surface receptors? 1. Receptor Guanylyl Cyclase: produces cGMP 2. RTK: phosphorylate tyrosine residues leading to association of signalling molecules and cascade 3. TK Associated Receptors: associate with proteins having TK activity 4. Receptor Tyrosine Phosphates: Removes phosphate on tyrosine residues 5. Receptor Serine/Threonine Kinases: phosphorylate specific Serine/Threonine residues on...

Lipinski's rule of 5 - ANSWER-- Poor absorption or permeation are more likely when: 1. mass greater than 500 Da 2. highly lipophilic - logP > 5 3. more than 5 hydrogen bond donors 4. more than 10 hydrogen bond acceptors Partition coefficient - ANSWER-p = C(octanol)/C(water) - ratio of the equilibrium concentrations of dissolved substance in a two-phase system containing two largely immiscible solvents (water & octanol) - Log10(P) Improved Lipinski Parameters - ANSWER-1. Partition...

UNC Biol 205 Exam 2 Questions With Verified Answers when cells respond to an extracellular signal, they most often convert the information carried by this molecule from one form to another. What is this process called? - answersignal transduction When does signal transduction begin? - answerwhen the receptor on a target cell recieves and incoming extracellular signal and then produces intracellular signaling molecules that alter cell behavior extracellular signal molecules, released loca...

1) What is desensitization? 2) What kind of cell receptors can this happen to? - Answer-1) When a cell decreases the amount of receptors on its surface to decrease the amount of response that the cell has to a ligand/stimulus 2) Can happen to any cell surface signalling receptor How is the endocytic pathway mediated? - Answer-Clathrin based endocytosis Describe the endocytic pathway in a stepwise fashion - Answer-1) Plasma membrane breaks off into free floating vesicles in the cytoplasm 2...

UNC Biol 205 Exam 2 Questions With Verified Answers when cells respond to an extracellular signal, they most often convert the information carried by this molecule from one form to another. What is this process called? - answersignal transduction When does signal transduction begin? - answerwhen the receptor on a target cell recieves and incoming extracellular signal and then produces intracellular signaling molecules that alter cell behavior extracellular signal molecules, released loca...

when cells respond to an extracellular signal, they most often convert the information carried by this molecule from one form to another. What is this process called? - Answer-signal transduction When does signal transduction begin? - Answer-when the receptor on a target cell recieves and incoming extracellular signal and then produces intracellular signaling molecules that alter cell behavior extracellular signal molecules, released locally example: inflammation regulation at site of infe...