Nur 641e mid term exam Study guides, Class notes & Summaries

Exam (elaborations) NUR-641E Mid-Term Exam Study Guide (NUR641) with 100% correct answers Note: Read the questions: the questions only have one answer unless the question specifically states there is more than one correct answer. Understand what a prodrug is, and activation/inactivation by liver enzymes, and how it differs from active drugs. The liver is the principal site of drug metabolism. Although metabolism typically inactivates drugs, some drug metabolites are pharmacologically active...

NUR-641E Mid-Term Exam Study Guide ANSWERED SO FAR Understand what a prodrug is, and activation/inactivation by liver enzymes, and how it differs from active drugs. The liver is the principal site of drug metabolism. Although metabolism typically inactivates drugs, some drug metabolites are pharmacologically active—sometimes even more so than the parent compound. An inactive or weakly active substance that has an active metabolite is called a prodrug, especially if designed to deliver t...

NUR-641E Mid-Term Exam Study Guide Note: Read the questions: the questions only have one answer unless the question specifically states there is more than one correct answer. ANSWERED SO FAR Understand what a prodrug is, and activation/inactivation by liver enzymes, and how it differs from active drugs. The liver is the principal site of drug metabolism. Although metabolism typically inactivates drugs, some drug metabolites are pharmacologically active—sometimes even more so than the p...

NUR-641E Mid-Term Exam Study Guide Note: Read the questions: the questions only have one answer unless the question specifically states there is more than one correct answer. ANSWERED SO FAR Understand what a prodrug is, and activation/inactivation by liver enzymes, and how it differs from active drugs. Know what Bioavailability (BA) Bioavailability is affected by chemical instability, solubility and first-pass metabolism Bioequivalence does not affect bioavailability Understand what the Cyto...

Understand what a prodrug is, and activation/inactivation by liver enzymes, and how it differs from active drugs. The liver is the principal site of drug metabolism. Although metabolism typically inactivates drugs, some drug metabolites are pharmacologically active—sometimes even more so than the parent compound. An inactive or weakly active substance that has an active metabolite is called a prodrug, especially if designed to deliver the active moiety more effectively. Know what Bioavai...

NUR-641E Mid-Term Exam Study Guide NUR-641E Mid-Term Exam Study Guide NUR-641E Mid-Term Exam Study Guide

NUR-641E Mid-Term Exam Study Guide Understand what a prodrug is, and activation/inactivation by liver enzymes, and how it differs from active drugs. Know what Bioavailability (BA) Bioavailability is affected by chemical instability, solubility and first-pass metabolism Bioequivalence does not affect bioavailability Understand what the Cytochrome P450 system is in the liver A drug’s half-life determines how often the drug is administered? Steady state of a drug is reached in approximately 5 to...

NUR-641E Mid-Term Exam Study Guide Note: Read the questions: the questions only have one answer unless the question specifically states there is more than one correct answer. ANSWERED SO FAR Understand what a prodrug is, and activation/inactivation by liver enzymes, and how it differs from active drugs. Know what Bioavailability (BA) Bioavailability is affected by chemical instability, solubility and first-pass metabolism Bioequivalence does not affect bioavailability Understand what the Cytochr...