Doac Study guides, Class notes & Summaries

Final Exam: NR567/ NR 567 (Latest 2024/ 2025 Update) Advanced Pharmacology for the AGACNP Review| Questions and Verified Answers| 100% Correct – Chamberlain Q: Direct oral anticoagulants (DOAC) Oral Xa inhibitors Answer: Rivaroxaban (Xarelto) Apixaban (Eliquis) Edoxaban (Savaysa) Betrixaban (Bevyxxa) Q: DOAC MOA Answer: Inhibits factor Xain the final common pathway of clotting Q: DOAC monitoring Answer: none Q: DOAC dosing Answer: Rapid onset of action, ...

Based on the readings, which DOAC has the shortest half-life yet is dosed once daily? A. Apixaban B. Rivaroxaban C. Dabigatran C All the DOACs have a short onset of action; however, which two require "bridging" with a parenteral anticoagulant for the treatment of DVT/PE? A. Dabigatran and rivaroxaban B. Dabigatran and apixaban C. Dabigatran and edoxaban D. None of the DOACs require bridging B At what degree of hepatic dysfunction should rivaroxaban be avoided? A. Child-Pugh...

Limitations of warfarin - Answer Requires routine INR monitoring Frequent dose adjustments Has many interactions Delayed onset - often requiring concomitant parenteral anticoagulant Benefits of warfarin - Answer Established monitoring assay (can establish if patient is under or over coagulated - doesn't exist for DOACs) Extensive clinical experience No dosage adjustment for renal dysfunction (DOACs do) More experience with reversal agents Inexpensive 2 types of D...

MOA - Answer Directly blocks Xa and thrombin (works immediately) Drug: Dabigatran (direct thrombin inhibitor) - Answer Pradaxa Drug: Rivaroxaban (direct factor Xa inhibitor) - Answer Xarelto Drug: Apixaban (direct factor Xa inhibitor) - Answer Eliquis Drug: Edoxaban (direct factor Xa inhibitor) - Answer Savaysa

DOAC questions with correct answers

DOAC (Direct oral anticoagulants) questions with correct answers

ESOP Pharmacology: DOACs questions with correct answers

how often do you screen for hypothyroidism after > 35 YO every 5 years T4 Levothyroxine T3 Liothyronine Subclinical TSH range 5-9 Starting dose Levothyroxine in healthy adult 1.6 mcg/kg/day If elderly or CAD what is the starting dose levothyroxine 12.5-25 mcg/day Amiodarone can induce ____thyroidism in iodine deficiency hyperthyroidism TSH offers positive/negative feedback from _____ gland pituitary Definitive treatment for hyper...

MOA of DOACs - Answer direct factor Xa inhibitor MOA of dabigatran - Answer direct thrombin inhibitor dosing of dabigatran for VTE - Answer usual: 150 mg PO BID after 5-10 days of injectable anticoagulant renal: contraindicated if CrCl <30 ml/min monitoring for dabigatran - Answer no lab tests are necessary due to predictable dose response -might be necessary when life-threatening bleeding or prior to emergent surgery: PTT efficacy of dabigatran - Answer -no lab ...

Direct acting oral anticoagulants (DOACs) questions with correct answers