Tufts Study guides, Class notes & Summaries

According to textbooks, local anesthetics fall into the following classes in terms of duration of action... wha tis short? - ANSWER Procaine What is moderate? - ANSWER Prilocaine, mepivicaine, lidocaine What is long? - ANSWER Bupivacaine, tetracaine, etidocaine How does propranolol interact with lidocaine? - ANSWER 1. By slowing down the heart via beta receptor blockade, blood delivery (and lidocaine) to the liver is reduced, thus lidocaine remains in the systemic circulation longer and ca...

Prilocaine can cause - ANSWER methoglobinemia Esther LAs. They are metabolized in the... - ANSWER Procaine, tetracaine, cocaine, benzocaine. Plasma What must be true for a LA to penetrate tissue membranes? - ANSWER Non-ionized (free base form) What drug can prolong the effect of Lidocaine? - ANSWER Propanolol (competes for metabolism in liver, slows heart)

Which of the following is a local anesthetic subject to inactivation by plasma esterases? a) procaine b) lidocaine c) prilocaine d) mepivacaine e) bupivacaine - procaine - only ester listed, rest are amides Procaine differs from lidocaine in that a) procaine is a p-aminobenzoic acid ester and lidocaine isn't b) lidocaine is meta-aminobenzoic acid ester and procaine isn't c) the duration of action of procaine is longer than that of an equal dose of lidocaine d) procaine hydrochlori...

Prilocaine can cause - methoglobinemia Esther LAs. They are metabolized in the... - Procaine, tetracaine, cocaine, benzocaine. Plasma What must be true for a LA to penetrate tissue membranes? - Non-ionized (free base form) What drug can prolong the effect of Lidocaine? - Propanolol (competes for metabolism in liver, slows heart) High plasma levels of LA cause.....even higher plasma levels cause... - Depression of CNS Inhibitors....shuts down respiration This disease makes you more s...

List 3 esters - ANSWER Procaine Tetracaine Cocaine Where are amides metabolized? - ANSWER Liver Where are esters metabolized? - ANSWER Pseudocholinesterases in plasma What drug group has the most consistent drug structure? - ANSWER LA What LA causes methemoglobinemia? - ANSWER Prilocaine

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Neuroscience EXAM 1– USA (Latest 2023/ 2024 Update) Questions and Verified Answers| 100% Correct| Grade A Q: function of brainstem Answer: basic bodily functions necessary for survival (e.g. HR, BP, RR) Q: cephalic flexure Answer: divides brain and brainstem Q: cervical flexure Answer: divides brainstem from spinal cord Q: defects during migration stage of development Answer: dyslexia, lissencephaly (smooth brain) Q: growth of brain due to: A...

Neuroscience EXAM 1– USA (Latest 2023/ 2024 Update) Exam Prep with Questions and Verified Answers| 100% Correct| Grade A Q: sulcus limitans Answer: works to divide dorsal from ventral tube Q: defects during migration stage of development Answer: dyslexia, lissencephaly (smooth brain) Q: cranial nerve development Answer: 1st: swallow & gag (14 weeks)-->V, VII, IX, X, XII 2nd: visual motor (25 weeks)-->II, III, IV, VI 3rd: hearing (28 weeks)-->VIII ...