Structures and functions of pattern recogniton receptors in mammalian immune systems Consequences of ligand binding Diseases associated with aberrant signalling

Recent work on how MHC bound peptides may be spliced to produce novel epitopes

T helper subsets, their function and mechanisms of promoting differentiation

Factors associated with predisposition to autoimmunity. Proposed mechanisms of T1D pathogenesis Diabetic animal models

The different signalling pathways used by cytokine receptors, how signalling from different cytokines may interact and the consequences this may have for target cells.

How DCs are activated, mature, and contribute to innate and adaptive responses to varied pathogens.