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v Pathophysiology, Canadian Edition,
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2nd Edition by Kelly Power-Kean,
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Chapter 1 - 42 v v v v
,Table of Contents v v
PART ONE: BASIC CONCEPTS OF PATHOPHYSIOLOGY
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Unit 1: The Cell
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1. Cellular Biology v
2. Genes and Genetic Diseases
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3. Epigenetics and Disease v v
4. Altered Cellular and Tissue Biology
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5. Fluids and Electrolytes, Acids and Bases
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Unit 2: Mechanisms of Self-Defense
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6. Innate Immunity: Inflammation and Wound Healing
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7. Adaptive Immunity v
8. Infection and Defects in Mechanisms of Defense
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9. Stress and Disease
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Unit 3: Cellular Proliferation: Cancer
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10. Biology of Cancer v v
11. Cancer Epidemiology v
12. Cancer in Children and Adolescents
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PART TWO: BODY SYSTEMS AND DISEASES
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Unit 4: The Neurologic System
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13. Structure and Function of the Neurologic System v v v v v v
14. Pain, Temperature, Sleep, and Sensory Function
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15. Alterations in Cognitive Systems, Cerebral Hemodynamics and Motor Function
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16. Disorders of the Central and Peripheral Nervous Systems and Neuromuscular Junction
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17. Alterations of Neurologic Function in Children v v v v v
Unit 5: The Endocrine System
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18. Mechanisms of Hormonal Regulation v v v
19. Alterations of Hormonal Regulation v v v
Unit 6: The Hematologic System
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20. Structure and Function of the Hematologic System v v v v v v
21. Alterations in Hematologic Function v v v
22. Alterations of Hematologic Function in Children v v v v v
Unit 7: The Cardiovascular and Lymphatic Systems
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23. Structure and Function of the Cardiovascular and Lymphatic Systems
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24. Alterations of Cardiovascular Function v v v
25. Alterations of Cardiovascular Function in Children v v v v v
Unit 8: The Pulmonary System
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26. Structure and Function of the Pulmonary System v v v v v v
27. Alterations of Pulmonary Function v v v
28. Alterations of Pulmonary Function in Children v v v v v
Unit 9: The Renal and Urologic Systems
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29. Structure and Function of the Renal and Urologic Systems
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30. Alterations of Renal and Urinary Tract Function v v v v v v
31. Alterations of Renal and Urinary Tract Function in Children v v v v v v v v
,Unit 10: The Reproductive Systems
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32. Structure and Function of the Reproductive Systems
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33. Alterations of the Female Reproductive System
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34. Alterations of the Male Reproductive System
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Unit 11: The Digestive System
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35. Structure and Function of the Digestive System
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36. Alterations of Digestive Function
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37. Alterations in Digestive Function in Children
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Unit 12: The Musculoskeletal and Integumentary Systems
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38. Structure and Function of the Musculoskeletal System
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39. Alterations of Musculoskeletal Function
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40. Alterations of Musculoskeletal Function in Children
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41. Structure, Function, and Disorders of the Integument
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42. Alterations of the Integument in Children
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, Chapter 01: Cellular Biology
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MULTIPLE CHOICE v
1. A student is observing a cell under the microscope. It is observed to have supercoiled DNA with
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histones. Which of the following would also be observed by the student?
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a. A single circular chromosome
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b. A nucleus v
c. Free-floating nuclear material v v
d. No organelles v
ANS: B v
The cell described is a eukaryotic cell, so it has histones and a supercoiled DNA within its
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nucleus; thus, the nucleus should be observed. A single circular chromosome called a
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prokaryote contains free-floating nuclear material but has no organelles.
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REF: p. 2 v v
2. A nurse is instructing the staff about cellular functions. Which cellular function is the nurse
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v describing when an isolated cell absorbs oxygen and uses it to transform nutrients to energy?
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a. Metabolic absorption v
b. Communication
c. Secretion
d. Respiration
ANS: D v NURSINGTB.COM
The cell’s ability to absorb oxygen is referred to as respiration while its communication ability
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involves maintenance of a steady dynamic state, metabolic absorption provides nutrition, and
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secretion allows for the synthesizing of new substances.
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REF: p. 2 v v
3. A eukaryotic cell is undergoing DNA replication. In which region of the cell would most of the
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genetic information be contained?
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a. Mitochondria
b. Ribosome
c. Nucleolus
d. Nucleus Cytoplasm v
ANS: C v
The region of the cell that contains genetic material, including a large amount of ribonucleic acid,
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most of the DNA, and DNA-binding proteins, is the nucleolus, which is located within the cell’s
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nucleus. Mitochondria is associated with cellular respiration, while ribosomes are involved with
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protein manufacturing. Cytoplasm is a fluid filling that is a component of the cell.
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REF: p. 2 v v
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