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PC705 MODULE 2 REVIEW | ADVANCED PATHOPHYSIOLOGY STUDY GUIDE, PRACTICE QUESTIONS & EXAM PREP 2026/2027

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PC705 MODULE 2 REVIEW | ADVANCED PATHOPHYSIOLOGY STUDY GUIDE, PRACTICE QUESTIONS & EXAM PREP 2026/2027

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PC705 MODULE 2 REVIEW|ADVANCED
PATHOPHYSIOLOGY STUDY GUIDE, PRACTICE
QUESTIONS & EXAM PREP 2026/2027

1 of 137




Term



Primary Hypertension Patho



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nonmodifiable: >50 years, men (higher risk), family hx of cardiac diseases
modifiable: smoking, htn, diabetes, dyslipidemia (high cholesterol), obesity




normal: <120/80
elevated: 120-129/<80
stage 1: 130-139/80-89
stage 2: >140/90




likely multi-factorial (genetics, environment); strong associations with obesity,
high salt intake, physical inactivity; may develop resistance to vasodilation and

, increased sympathetic activity




acute: rapid progression
chronic: slow progression


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2 of 137

Term



Myeloid Leukemia vs Lymphoid Leukemia



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EF: <40 % >40%
Problem: impaired contractility
impaired relaxation coronary artery disease (CAD), heart
Vent. Remodel: dilation hypertrophy failure (HF), and hypertension
Causes: MI, cardiomyopathy HTN,
aging




myeloid: affecting granulocytes
iron is essential for Hgb production,
or monocytes
oxygen transport, and muscle
lymphoid: affecting
function
lymphocytes


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3 of 137

,Term



Tx of CVI



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lifestyle changes, compression therapy, medications (diuretics, venoactive
drugs to improve vein tone), surgical procedures (vein ablation, sclerotherapy,
vein stripping to remove damaged veins or close damaged veins)




low RBC- anemia
low platelets- bleeding tendencies
(bone marrow suppression: anemia, thrombocytopenia, leukopenia)
(cell accumulation: lymphadenopathy, splenomegaly, infection prone- fever and
infections)




ABI, doppler ultrasound, angiography




people that live in high altitudes, have sleep apnea or heart disease adapt to lower
oxygen tension in the air by increasing RBCs to compensate for decreased oxygen
carrying capacity


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, 4 of 137

Term



Squamous Cell Carcinoma originates from



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sulcular epithelium squamous epithelium




cuboidal epithelium transitional epithelium


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5 of 137

Term



Types of Microcytic Anemia



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B12 & folate deficiency




Iron deficiency, Anemia of chronic disease (ACD), Thalassemia, Sideroblastic,
Lead poisioning

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