Updated/Latest Understanding Pathophysiology 6th Edition Sue E. Huether Kathryn L. McCance Test Bank Complete Chapters 1–42 Comprehensive Pathophysiology Resource Questions Answers Rationales Disease Processes Clinical Case Studies NCLEX Review Study Guid

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Understanding Pathophysiology 6th Edition L
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By: Sue E. Huether; Kathryn L. McCance
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PART ONE: BASIC CONCEPTS OF PATHOPHYSIOLOGY
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Unit 1: The Cell
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Chapter 1: Cellular Biology L
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Chapter 2. Genes and Genetic Diseases T L T L T L T L T L


Chapter 3. Epigenetics and Disease (NEW)
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Chapter 4. Altered Cellular and Tissue Biology
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Chapter 5. Fluids and Electrolytes, Acids and Bases
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Unit 2: Mechanisms of Self-Defense
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Chapter 6. Innate Immunity: Inflammation and Wound Healing
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Chapter 7. Adaptive Immunity
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Chapter 8. Infection and Defects in Mechanisms of Defense
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Chapter 9. Stress and Disease
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Unit 3: Cellular Proliferation: Cancer
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Chapter 10. Biology of Cancer
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Chapter 11. Cancer Epidemiology
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Chapter 12. Cancer in Children and Adolescents
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PART TWO: BODY SYSTEMS AND DISEASES
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Unit 4: The Neurologic System
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Chapter 13. Structure and Function of the Neurologic System
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Chapter 14. Pain, Temperature, Sleep, and Sensory Function
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Chapter 15. Alterations in Cognitive Systems, Cerebral Hemodynamics and Motor Function
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Chapter 16. Disorders of the Central and Peripheral Nervous Systems and Neuromuscular Junction
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Chapter 17. Alterations of Neurologic Function in Children
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Unit 5: The Endocrine System
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Chapter 18. Mechanisms of Hormonal Regulation
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Chapter 19. Alterations of Hormonal Regulation
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Unit 6: The Hematologic System
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Chapter 20. Structure and Function of the Hematologic System
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Chapter 21. Alterations in Hematologic Function
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Chapter 22. Alterations of Hematologic Function in Children
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Unit 7: The Cardiovascular and Lymphatic Systems
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Chapter 23. Structure and Function of the Cardiovascular and Lymphatic Systems
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Chapter 24. Alterations of Cardiovascular Function
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Chapter 25. Alterations of Cardiovascular Function in Children
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Unit 8: The Pulmonary System
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Chapter 26. Structure and Function of the Pulmonary System
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Chapter 27. Alterations of Pulmonary Function
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Chapter 28. Alterations of Pulmonary Function in Children
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Unit 9: The Renal and Urologic Systems
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Chapter 29. Structure and Function of the Renal and Urologic Systems
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Chapter 30. Alterations of Renal and Urinary Tract Function
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Chapter 31. Alterations of Renal and Urinary Tract Function in Children
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Unit 10: The Reproductive Systems
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Chapter 32. Structure and Function of the Reproductive Systems
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Chapter 33. Alterations of the Female Reproductive System
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Chapter 34. Alterations of the Male Reproductive System
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Unit 11: The Digestive System
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Chapter 35. Structure and Function of the Digestive System
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Chapter 36. Alterations of Digestive Function
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Chapter 37. Alterations in Digestive Function in Children
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Unit 12: The Musculoskeletal and Integumentary Systems
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Chapter 38. Structure and Function of the Musculoskeletal System
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Chapter 39. Alterations of Musculoskeletal Function
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,Chapter 40. Alterations of Musculoskeletal Function in Children
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Chapter 41. Structure, Function, and Disorders of the Integument
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Chapter 42. Alterations of the Integument in Children
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,Chapter 01: Cellular Biology
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Huether & McCance: Understanding Pathophysiology, 6th Edition
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MULTIPLE CHOICE L
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1. A student is observing a cell under the microscope. It is observed to have supercoiled DNA
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with histones. Which of the following would also be observed by the student?
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a. A single circular chromosome T L L
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b. A nucleus L
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c. Free-floating nuclear material L
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d. No organelles L
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ANS: B T L



The cell described is a eukaryotic cell, so it has histones and a supercoiled DNA within its
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nucleus; thus, the nucleus should be observed. A single circular chromosome called a
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prokaryote contains free-floating nuclear material but has no organelles.
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REF: p. 2 L
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2. A nurse is instructing the staff about cellular functions. Which cellular function is the nurse
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describing when an isolated cell absorbs oxygen and uses it to transform nutrients to energy?
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a. Metabolic absorption L
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b. Communication
c. Secretion
d. Respiration
ANS: D L
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The cell’s ability to absorb oxygen is referred to as respiration while its communication ability
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involves maintenance of a steady dynamic state, metabolic absorption provides nutrition, and
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secretion allows for the synthesizing of new substances.
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REF: p. 2 L
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3. A eukaryotic cell is undergoing DNA replication. In which region of the cell would most of
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L
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a. Mitochondria
b. Ribosome
c. Nucleolus
d. Nucleus Cytoplasm L
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ANS: C L
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The region of the cell that contains genetic material, including a large amount of ribonucleic
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acid, most of the DNA, and DNA-binding proteins, is the nucleolus, which is located within
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the cell’s nucleus. Mitochondria is associated with cellular respiration, while ribosomes are
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involved with protein manufacturing. Cytoplasm is a fluid filling that is a component of the
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cell.
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, 4. Which of the following can remove proteins attached to the cell’s bilayer by dissolving the
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a. Peripheral membrane proteins L
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b. Integral membrane proteins T L L
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c. Glycoproteins
d. Cell adhesion molecules L
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ANS: B L
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Proteins directly attached to the membrane bilayer can be removed by the action of integral
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membrane proteins that dissolve the bilayer. Peripheral membrane proteins reside at the
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surface while cell adhesion molecules are on the outside of the membrane. Glycoprotein
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marks cells and does not float.
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REF: p. 7 L
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5. Which of the following can bind to plasma membrane receptors?
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a. Oxygen
b. Ribosomes
c. Amphipathic lipids T L



d. Ligands
ANS: D L
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Ligands are the only specific molecules that can bind with receptors on the cell membrane.
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REF: p. 9 L
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6. A nurse is reviewing a report from a patient with metastatic cancer. What alternation in the
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extracellular matrix would s uNp p oRr t t hIe dG
iagnBo.
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metastatic cancer?
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a. Decreased fibronectin L
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b. Increased collagen L
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c. Decreased elastin L
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d. Increased glycoproteins L
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ANS: A L
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Only a reduced amount of fibronectin is found in some types of cancerous cells, allowing them
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to travel or metastasize.
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REF: p. 10 L
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7. Which form of cell communication is used to relate to other cells in direct physical contact?
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a. Cell junction T L



b. Gap junction L
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c. Desmosome
d. Tight junction T L




ANS: A L
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Cell junctions hold cells together and permit molecules to pass from cell to cell.
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Gap junctions allow for cellular communication between cells. Neither desmosomes nor tight
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junctions are associated with cellular communication.
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REF: p. 11 L
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