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bt EDITION McCANCE ALL CHAPTERS 1-50
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bt QUESTIONS & ANSWERS 2025.
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,Chapter1-49 t
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Chapter01:CellularBiology bt bt bt
Rogers:McCance&Huether’sPathophysiology,9thEdition
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MULTIPLE CHOICE bt
1. Which statement best describes the cellular function of metabolic absorption?
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a. Cells can produce proteins. bt bt bt
b. Cells can secrete digestive bt bt bt
enzymes. bt
c. Cells can take in and use bt bt bt bt bt
nutrients. bt
d. Cells can synthesize fats. bt bt bt
ANS: b t C
In metabolic absorption, all cells take in and use nutrients and other substances
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from their surroundings. The remaining options are not inclusive in their
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descriptions of cellular metabolic absorption.
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DIF: Cognitive Level: Remembering bt bt
2. Whereis most of a cell’s genetic information, including RNA and DNA, contained?
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a. Mitochond
ria
b. Ribosome
c. Nucleolus
d. Lysosome
ANS: b t C
The nucleuscontains the nucleolus, a small dense structure composed largely
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of RNA, most of the cellular DNA, and the DNA-binding proteins, such as the
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histones, which regulate its activity. The mitochondria are responsible for
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cellular respiration and energy production.
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Ribosomes’ chieffunction is to provide sites forcellularprotein synthesis. bt bt bt bt bt bt bt bt bt bt
Lysosomes function as the intracellular digestive system.
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DIF: Cognitive Level: Remembering bt bt
3. Which component of the cell produces hydrogen peroxide (H2O2) byusing
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oxygen to remove hydrogen atoms from specific substrates in an oxidative
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reaction?
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a. Lysosome
s
b. Peroxisom
es
c. Ribosome
, s
d. Endosome
ANS: b t B
, Peroxisomes are so named because they usually contain enzymes that use oxygen to
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remove hydrogen atoms from specific substrates in an oxidative reaction that produces
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H2O2, which is a powerful oxidant and potentially destructive if it accumulates or
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escapes from peroxisomes. Ribosomes are RNA-protein complexes (nucleoproteins)
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that are synthesized in the nucleolus and secreted into the cytoplasm through pores in
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the nuclear envelope called nuclear pore complexes. Lysosomes are saclike structures
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that originate from the Golgi complex and contain more than 40 digestive enzymes
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called hydrolases, which catalyze bonds in proteins, lipids, nucleic acids, and
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carbohydrates. An endosome is a vesical that has been pinched off from the cellular
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membrane.
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DIF: Cognitive Level: Remembering bt bt
4. Which cell component is capable of cellular autodigestion whenit is
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released during cell injury?
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a. Ribosome
b. Golgi complex bt
c. Smooth endoplasmic bt
reticulum
bt
d. Lysosomes
ANS: b t D
Thelysosomal membrane acts as a protective shield between the powerful
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digestive enzymes within the lysosome and the cytoplasm, preventing their
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leakage into the cytoplasmic matrix. Disruption of the membrane by various
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treatments or cellular injury leads to a release of the lysosomal enzymes,
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which can then react with their specific substrates, causing cellular self-
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digestion. The chief function of a ribosome is to provide sites for cellular
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protein synthesis. The Golgi complex is a network of flattened, smooth vesicles
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and membranes often located near the cell nucleus. The smooth endoplasmic
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reticulum is involved in steroid hormone production and removing toxic
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substances from the cell.
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DIF: Cognitive Level: Remembering bt bt
5. Which cAMP-mediated response is related to antidiuretic hormone?
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a. Increased heart rate and force of bt bt bt bt bt
contraction
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b. Secretion of cortisol bt bt
c. Increased retention of water bt bt bt
d. Breakdown of fat bt bt
ANS: b t C
Antidiuretic hormone leads to increased retention of water in the body. bt bt bt bt bt bt bt bt bt bt
Epinephrine causes increases in heart rateand force ofcontraction. Increased
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cortisol secretion is due toACTH. Breakdown of fat is due to glucagon.
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DIF: Cognitive Level: Remembering bt bt
6. During which phase of the cell cycle is DNA synthesized? bt bt bt bt bt bt bt bt bt