NAPLEX Practice Exam Questions and Answers A Level based

NAPLEX Practice Exam Questions and Answers A Level based Which of the following is true regarding niacin formulations? Answer A Niaspan is controlled-release niacin; it causes less flushing but more hepatotoxicity. B Niaspan is extended-release niacin; it causes less flushing and less hepatotoxicity. C Slo-Niacin is sustained-release niacin; it causes less hepatotoxicity but is the most expensive agent. D Slo-Niacin is interchangeable with other niacin formulations. E Niacin decreases both LDL and triglycerides and is one of the classes of drugs that does not cause hepatotoxicity. - B TR is beginning amiodarone therapy for new-onset atrial fibrillation. Which of the following statements is correct? Past Medical History: Heart failure Myocardial infarctions X 2 Hypertension Glaucoma Benign prostatic hypertrophy Medications: Lisinopril 20 mg PO daily Carvedilol 25 mg PO BID Aspirin 81 mg PO daily Lasix 40 mg PO daily Digoxin 0.25 mg PO daily Xalatan 1 drop QHS Proscar 5 mg PO daily Answer A Amiodarone is a p-glycoprotein inhibitor; the dose of digoxin should be decreased by up to 50%. B Amiodarone is a p-glycoprotein inducer; the dose of digoxin should be decreased by 25%. C Amiodarone is a CYP 3A4 inhibitor; the dose of digoxin should be increased by up to 50%. D Amiodarone should not be used in patients with heart failure. E Amiodarone is contraindicated in patients receiving digoxin. - A Medical Plaza Pharmacy frequently prepares Magic Mouthwash, a mucosal liquid for chemotherapy patients with mucositis. Based on the master formula record and prescription information below, what would be the appropriate beyond-use-date for this compounded product? Magic Mouthwash Mucosal Liquid Viscous lidocaine 2% 80 mL Mylanta 80 mL Diphenhydramine 12.5 mg/5 mL 80 mL Nystatin suspension 80 mL Prednisolone 15 mg/5 mL 80 mL Distilled water 80 mL Storage: store at room temperature. Instructions: Swish, gargle and spit 5 - 10 mL Q6H PRN. Do not swallow. Answer A 7 days B 14 days C 30 days D 45 days E 60 days - C Question Which of the following statements is true about the progestin-only daily contraceptive pill? Answer A Most products contain medroxyprogesterone with estradiol. B The progestin-only pill should be avoided in women who are breastfeeding. C If a pill is missed and taken 3 or more hours later, a back-up contraceptive method is needed for 48 hours. D The first pack must be started on the Sunday after menstruation begins; there are 21 active pills and 7 inactive pills. E The progestin-only pill is more effective than estrogen/progesterone combinations. - C Question A 43 year-old female patient with type 2 diabetes and normal renal function started taking Januvia 100 mg daily in the morning. Which of the following is correct regarding Januvia? (Select ALL that apply.) Answer A The generic name is saxagliptin. B It is a glucagon-like peptide (GLP-1) agonist. C It is an alpha-glucosidase inhibitor. D It is weight neutral. E It can cause pancreatitis. - D,E Question TC is picking up a prescription for pancreatic enzymes for his son. How should the pharmacist counsel him regarding administration of pancreatic enzymes? Answer A Give half of the dose before eating each meal and the other half of the dose 1 hour after eating each meal. B Give this medication twice daily, first thing in the morning and at bedtime, with a full glass of water. C The capsules will taste better if they are kept in the refrigerator and only removed immediately before each meal and snack. D If the child has difficulty swallowing the capsules, they can be sprinkled into his mouth and washed down with a full glass of water. E Give the full dose before each meal and 1/2 of the normal dose with each snack. - E Question A pharmacist is compounding an anesthetic cream by mixing an equal amount of lidocaine and prilocaine powder. Separately, the lidocaine powder and prilocaine powder are solid. But when they are mixed together, the powder mixture begins to melt. What best describes this type of compounded preparation? Answer A Sedimentation B Precipitation C Emulsion D Eutectic E Reactive - D Question A patient is using Opana ER tablets. Which of the following statements concerning Opana ER is correct? Answer A Opana ER should be taken on an empty stomach. B If Opana ER is ingested with alcohol there will be reduced absorption of the drug, causing lack of analgesic efficacy. C Opana ER can be used in patients with moderate to severe liver impairment. D Opana ER is an antagonist at the mu opioid receptor. E The chemical name is oxycodone. - A Question A pharmacy resident completes a retrospective study of patients in a clinic who were prescribed amiodarone. The resident examines the medical profile of each patient to determine if the amiodarone caused hyperthyroidism. He then compares the risk of hyperthyroidism to a group of patients who did not receive amiodarone. This is an example of what type of study? Answer