Biochem final Study guides, Class notes & Summaries

How is malonyl-CoA formed? correct answer: Carboxylation of acetyl-CoA to form malonyl-CoA requires two steps (both use acetyl-CoA carboxylase). 1. The enzyme, complexed with biotin, acquires CO2 from HCO3 - a. Requires 1 ATP 2. The carbon is transferred to acetyl-CoA to form malonyl-CoA The overall reaction is irreversible and commits the molecule to fatty acid synthesis. Phosphate is added to HCO3 - and then removed so that biotin-carboxylase can grab the carbon. The carbon is donated to...

UNE Medical Biochem Final Exam Questions With Solved Answers Scored A+

A 3-year-old male is brought to the emergency department by his parents. He is unconscious on admittance and his blood glucose was 15 mg/dl, ( normal 75 - 105 mg/dl). Further testing showed this individual had a deficiency in carnitine. Based on this diagnosis you would also expect which of the following to be true with regards to metabolism: correct answer: This patient would have elevated levels of circulating free fatty acids. A 7-year old female is recently diagnosed with type 1 diabetes...

UNE Medical Biochem Final Exam Questions With Solved Answers Scored A+ The cellular uptake of LDL increase intracellular cholesterol levels. This has which of the following impacts on de novo cholesterol synthesis? Increases degradation of HMG-CoA reductase Dietary cholesterol is primarily transported in the body by which of the following lipoproteins? Chylomicrons. Cholesterol and TG from diet are transported from intestine to liver via chylomicrons. The LDL receptor is also highly re...

UNE Biochem Final Exam 2023/2024 A 3-year-old male is brought to the emergency department by his parents. He is unconscious on admittance and his blood glucose was 15 mg/dl, ( normal 75 - 105 mg/dl). Further testing showed this individual had a deficiency in carnitine. Based on this diagnosis you would also expect which of the following to be true with regards to metabolism: This patient would have elevated levels of circulating free fatty acids. A 7-year old female is recently diagnosed wi...

In the liver, which of the following key inhibitory events ensures that newly synthesized palmitoyl-CoA is not immediately oxidized? Carnitine palmitoyl transferase-I (CPTI) by palmitoylcarnitine Carnitine palmitoyl transferase-II (CPTII) by acetyl-CoA Acyl-CoA synthetase by malonyl CoA Carnitine palmitoyl transferase-I (CPTI) by malonyl-CoA Carnitine acylcarnitine translocase (CAT) by palmitoyl-CoA correct answer: Carnitine palmitoyl transferase-I (CPTI) by malonyl-CoA Malony...

An individual goes to bed around 8 pm and doesn't wake up until 9 am the next morning. During this time, which of the following is the primary oxidizable substrate in the skeletal muscle? - Free fatty acids Under fasted conditions as described above, the skeletal muscle and liver would be oxidizing free fatty acids as a means of producing ATP. A well, 2-year-old girl presents to the clinic with symptoms of a viral illness. Her parents report she has had bouts of vomiting and diarrhea o...

UNE Biochem FINAL |83 Questions| With 100% Verified & Passed Solutions. An individual goes to bed around 8 pm and doesn't wake up until 9 am the next morning. During this time, which of the following is the primary oxidizable substrate in the skeletal muscle? Free fatty acids Under fasted conditions as described above, the skeletal muscle and liver would be oxidizing free fatty acids as a means of producing ATP. A well, 2-year-old girl presents to the clinic with symptoms of a viral ill...

BIOCHEM FINAL EXAM QUESTIONS AND ANSWERS

Under fasting conditions (ratio of insulin to glucagon <1), elevated glucagon will activate which of the following enzymes? correct answer: Hormone sensitive lipase The process of ketogenesis refers to the conversion of acetyl CoA to which of the following compounds? correct answer: D-3-hydroxybutyrate or B-hydroxybutyrate During the fasted state, lipolysis is facilitated by the action of hormone sensitive lipase. This enzyme requires which of the following post - translational modifi...