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PCOL 838 Exam Package Deal Questions and Verified Answers (2025 / 2026)
PCOL 838 Exam Package Deal Questions and Verified Answers (2025 / 2026)
Exam (elaborations)
Pcol 838 Genetic Exam 2025 Questions And Answers
Acrocentric - ANS the terminal location of the centromere on chromosomes 13, 14, 15, 21, 
and 22 
Allelic heterogeneity - ANS The situation on which allels at a single locus can produce one or 
more disease phenotypes 
Amorphic - ANS general term used to denot any unbalances chromosome complement 
Antimorphic - ANS pathogenic variants that, when present in heterozygous form opposite 
nonmutant allele, will result in a phenotype similar to homozygosity for loss-of-function alleles 
Ascertainment ...
Exam (elaborations)
Pcol 838 Liver Disease Exam 2025 Questions And Answers
Two predominant lobes - ANS The liver is anatomically separated into..... 
Posterior caudate and inferior quadrate lobes - ANS The lesser segments of the right lobe. 
Four sectors - ANS The liver is functionally differentiated into.... 
Hepatic portal vein (~75%) and hepatic arteries (~25%) - ANS The central veins receive a dual 
blood supply from the.... 
Portal vein/hepatic artery, central vein, hepatic vein, inferior vena cava - ANS What is the 
blood flow to the liver in order? 
PCOL 838 LIV...
Exam (elaborations)
Pcol 838 Exam 2 Review 2025 Questions And Answers
Blood circulation pathway - ANS ↷ Capillaries → Venules→ Veins→ Superior Vena Cava→ 
Right Atrium→ Tricuspid valve→ Right Ventricle→ Pulmonary valve→ Pulmonary arteries→ 
Lungs→ Pulmonary veins→ Left Atrium→ Bicuspid (Mitral) valve→ Left ventricle→ Aortic 
valve→ Aorta→ Arteries→ arterioles ↻ 
Role of blood vessels - ANS Transport materials 
Byproduct removal from tissues 
Specialized receptors and messengers on endothelium 
Cell Types in blood vessels - ANS...
Exam (elaborations)
Pcol838 - Disorders Of The Pancreas Exam 2025 Questions And Answers
What are the main exocrine functions of the pancreas? - ANS -to release digestive enzymes 
-to help with the digestion of food 
What are the two exocrine cell types of the pancreas? - ANS -acinar cells 
-ductal cells 
What is the function of acinar cells? - ANS -to secrete digestive enzymes into the pancreas 
What is the function of the ductal cells? - ANS -to secrete pancreatic juice that contains 
sodium bicarbonate, which neutralizes food 
PCOL838 - DISORDERS OF THE 
PANCREAS EXAM 2025 QUESTI...
Exam (elaborations)
Pcol 838 Disorders Of The Adrenal Cortex Exam 2025 Questions And Answers
What are the histologic layers of the adrenal cortex, and what steroids does each secrete? - 
ANS Zona glomerulosa (outer): aldosterone (mineralocorticoid) 
Zona fasciculata (middle): cortisol (glucocorticoid) 
Zona reticularis (inner): DHEA (androgen) 
Medulla: catecholamines (Epi,NE) 
What triggers glucocorticoid secretion? - ANS Corticotropin-releasing hormone (CRH) from 
hypothalamus stimulates the release of adrenocorticotropic hormone (ACTH) from anterior 
lobe of pituitary gland (1). 
PCO...
Exam (elaborations)
Pcol 838: Final Exam Study Guide 2025 Questions And Answers
What is a vector in terms of infectious disease? - ANS An organism that carries a pathogen 
Which of the following is a common example of a vector pathogen? 
a.) Malaria 
b.) COVID-19 
c.) Ebola 
d.) Tuberculosis - ANS a.) Malaria 
Which of the following are possible types of pathogens? 
a.) Fungus 
b.) Bacteria 
c.) Protozoa 
d.) Viruses 
PCOL 838: FINAL EXAM STUDY GUIDE 
2025 QUESTIONS AND ANSWERS 
2 @COPYRIGHT THESTAR 2025/2026 
e.) Misfolded proteins 
f.) All of the above - ANS f.) All of th...
Exam (elaborations)
Pcol 838: Exam 2 Study Guide 2025 Questions And Answers
The respiratory system is comprised of which of the following zones? Select all that apply. 
a.) Conducting zone 
b.) Blood zone 
c.) Apparatus zone 
d.) Respiratory zone - ANS A and D 
Conducting zone and Respiratory zone 
What is the conducting zone? 
a.) It forms a continuous passageway for air to move in and out of the lungs. 
b.) It is found deep inside the lungs and is made up of the respiratory bronchioles, alveolar 
ducts, and alveoli. - ANS a.) It forms a continuous passageway for air t...
Exam (elaborations)
Pcol838 Thyroid Disease Exam 2025 Questions And Answers
The thyroid gland synthesizes the hormones thyroxine (T4) and triiodothyronine (T3) which pair 
_____ that regulate the body's metabolic rate 
Iodine-containing amino acids 
What are thyroid hormones necessary for in infants, children, and adults? 
-Infants: normal CNS development 
-Children: skeletal growth (bone and muscle) 
-Adults: normal function 
The thyroid gland is highly ____ and has one of the highest rates of blood flow per gram of 
tissue of any organ 
Vascular 
The thyroid gland ...
Exam (elaborations)
Pcol 838 Renal Disease Exam 2025 Questions And Answers
Components of the urinary system 
kidneys → ureters → bladder → urethra 
(prostate if male) 
kidneys 
-produce urine 
-2 bean shaped organs located in middle back below rib cage 
-divided into outer cortex and inner medulla 
medulla contains 
renal pyramids and renal columns 
excretory duct system 
-transports urine 
-include ureter, renal pelvis, major calyces, and minor calyces 
ureter 
delivers urine into bladder 
PCOL 838 RENAL DISEASE EXAM 2025 
QUESTIONS AND ANSWERS 
2 @COPYRIGHT THE...
Exam (elaborations)
Pcol838: Liver Diseases Exam 2025 Questions And Answers
Anatomy of liver 
-Wrapped in tough fibrous capsule, covered by visceral peritoneum, divided into 2 lobes (left 
and right) 
-Can be differentiated functionally via the portal blood flow into 4 sectors, which are further 
divided into 8 segments 
Blood flow in liver 
-Hepatic portal system: the central veins receive dual blood supply from hepatic portal vein 
(~75%) and hepatic arteries (~25%) 
Portal vein/Hepatic artery → Central vein → Hepatic vein → Inferior vena cava 
-Hepatic portal v...
Exam (elaborations)
Pcol 838 Hypo-Pituitary Exam 2025 Questions And Answers
Function of the hypothalamus 
respond to deviations in set points (body temperature, blood volume, osmolality, satiety, fat 
content, body weight) 
set points that can change: 
body fat content 
body weight 
satiety 
set points that don't really tolerate change: 
body temp 
blood volume 
osmolality 
coordinated responses to set point deviations include 
PCOL 838 HYPO-PITUITARY EXAM 2025 
QUESTIONS AND ANSWERS 
2 @COPYRIGHT THESTAR 2025/2026 
nervous system: leads to behavior changes (i.e. inc...
Exam (elaborations)
Pcol 838 The Immune System. Exam 2025 Questions And Answers
What are the two arms of the immune system? 
- innate immunity 
- adaptive immunity 
what are mechanisms of innate immunity? 
- rapid response (minutes to hours) 
- fixed response 
- limited number of specificities 
- constant during response 
what are mechanisms of adaptive immunity? 
- slow response (days-weeks) 
PCOL 838 THE IMMUNE SYSTEM. EXAM 
2025 QUESTIONS AND ANSWERS 
2 @COPYRIGHT THESTAR 2025/2026 
- variable 
- numerous highly selective specificities 
- improve during response 
what ar...
Exam (elaborations)
Pcol838 Cardiovascular Disease Exam 2025 Questions And Answers
Prevalence of CV diseases 
1. Coronary Heart Disease 
2. Stroke 
3. Sudden cardiac arrest 
4. Atrial fibrillation 
5. HF 
6. Valvular disease 
What is the cardiac output rate? 
About 4-7 L/min 
How much blood is circulated per day? 
Around 7200 L 
What is chronotropy? 
Speed of contraction 
What is inotropy? 
Strength of contraction 
What is lusitropy? 
Muscular relaxation/diastolic fill 
Stroke volume problems are coronary diseases leading to _____ 
Cardiomyopathy 
What are stroke vol
Exam (elaborations)
Pcol838 Disorders Of The Endocrine Pancreas. Exam 2025 Questions And Answers
Function of the mouth 
Taste, chewing 
Function of the esophagus 
Transport 
Function of the liver 
Metabolism, detoxification, bile production 
Function of the small intestine 
Digestion, absorption 
Function of the cecum 
Storage 
Function of the saliva 
Lubrication, protection, digestion 
Function of the gallbladder 
Bile storage 
Function of the stomach 
Storage, grinding, mixing, digestion, acid secretion 
Function of the pancreas 
Enzymes, HCO3- buffer 
Function of the large intestine 
Flu...
Exam (elaborations)
Pcol 838 Exam 2 2025 Questions And Answers
What do the kidneys do? 
filter blood and produce urine 
Where are the kidneys located 
Paired, bean-shaped organs are located in the middle of your back, just below the rib cage 
How is the kidney divided? 
Divided into outer cortex and inner medulla (renal pyramids and columns) 
What does the excretory duct system do? 
transports urine 
What does the the ureter do? 
delivers urine into bladder 
What is the renal pelvis? 
expanded upper portion of ureter 
What are the major calyces? 
subdivisio...
Exam (elaborations)
Pcol838 Vascular Function And Disease Exam 2025 Questions And Answers
What are the roles of blood vessels? 
-Transport and delivery of raw materials to tissues and removal of byproduct from tissues 
-Recognition and communication with specialized receptors and messengers on endothelium 
What are endothelial cells? 
Single layer of cells lining the blood 
What do endothelial cells do? 
-Secrete growth regulators and vasoactive substances 
-Respond to changes in blood flow, stretch, circulating substances and inflammatory mediators 
What role do vascular smooth musc...
Exam (elaborations)
Pcol 838 Genetic Diseases Ii Part 2 Exam 2025 Questions And Answers
Osteogenesis imperfecta is a _____ (homogeneous/heterogenous) disease caused by mutation 
to genes involving type 1 collagen formation 
Heterogenous 
Osteogenesis imperfecta is an autosomal _____ (recessive/dominant) inheritance due to 
haploinsuffieciency or dominant negative mutants 
Dominant 
Type 1 OI is a mild autosomal dominant mutation that is ______ (amorphic, antimorphic, etc) 
that leads to short stature, postnatal fractures, bleu scleras, and hearing loss 
Amorphic-> normal but red...