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Exam (elaborations)
Antimicrobials SG
Antimicrobials 
 Differentiate Bacteriostatic and Bacterialcidal. 
 bactericidal – directly lethal to bacteria at clinically achievable concentrations 
 bacteriostatic – slow bacterial growth but do not cause cell death 
 What is the difference between broad spectrum and narrow spectrum? 
 Narrow – active against only a few species of microorganisms 
 Broad – active against a wide variety of microbes 
 Which is preferred? 
 Narrow-spectrum 
 antibiotic classifi...
Exam (elaborations)
Antimicrobials Part 2
Antimicrobials Part 2 
Bacteriostatic Inhibitors of Protein Synthesis: suppress growth, don’t kill 
Tetracyclines: “clyclines”; Tetracycline; Demeclocycline; Doxycycline; Minocycline 
What are they: Broad-spectrum antibiotics; Inhibit protein synthesis by inhibiting 
binding transfer RNA to messenger RNA; Increasing bacterial resistance has emerged 
Uses: Treatment of infectious disease (Rocky Mountain spotted fever); Treatment of 
acne; Peptic ulcer disease; Periodontal disease; Rheumat...
Exam (elaborations)
Antimicrobials part 5
Antimicrobials part 5 
Antiviral Agents I: Drugs for Non-HIV Viral Infections 
Antiviral Therapy: Our ability to treat viral infections remains limited; Viruses use biochemical machinery 
of host cells to reproduceDifficult to suppress viral replication without doing significant harm to the 
host; Antivirals suppress biochemical processes unique to viral reproduction 
Acyclovir [Zovirax]: Active only against members of the herpesvirus family; Agent of first choice for 
herpes simplex virus ...
Exam (elaborations)
Antimicrobials Part 3: Miscellaneous Antibacterial Drugs
Antimicrobials Part 3: Miscellaneous Antibacterial Drugs 
Fluoroquinolones “oxacins”: Broad-spectrum agents with multiple applications; Disrupt DNA replication 
and cell division; PO or IV; Resistance develops slowly but has become common in Neisseria 
gonorrhoeae 
Side Effects: generally mild but can cause tendon rupture (low risk)Usually affects Achilles 
tendon 
Contraindications: Avoid in patients younger than 18 years; Avoid in patients with myasthenia 
gravis; Risk to all patien...
Exam (elaborations)
ANTIMICROBIALS PART3
ANTIMICROBIALS 
PART3 
Lynda Jarrell, DNP, APRN,FNP-BC, CNE 
MISCELLANEOUS 
ANTIBACTERIAL 
DRUGS 
■ Broad-spectrum agents with multiple applications 
■ Disrupt DNA replication and cell division 
■ All can be administered orally or IV 
■ Resistance develops slowly but has become common in 
Neisseria gonorrhoeae 
Fluoroquinolones
Exam (elaborations)
Exam (elaborations) NURS 5344 Study Questions Module 8
Study Questions 
Module 8 
PUD 
• What are defense factors for PUD? 
• What are the causes of PUD? 
• What are the 3 ways antiulcer drugs work? 
• What are differenced in tx with H. pylori induced and NSAID induced 
ulcers? 
• How is healing monitored? 
• What level does gastric PH need to be to decrease Pepsin activity? 
PUD 2 
• What are the 3 types of H. pylori testing? 
• What is the minimum number of antibiotics to treat PUD? 
• What are the drugs used to treat PUD? 
•...