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ROSH REVIEW- ENDOCRINE QUESTIONS AND CORRECT ANSWERS

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Rosh Review- Endocrine Questions And Correct Answers

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27 pages

2025/2026

Institution PSL300

Course PSL300

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ROSH REVIEW- ENDOCRINE QUESTIONS AND CORRECT ANSWERS

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ROSH REVIEW- ENDOCRINE QUESTIONS
AND CORRECT ANSWERS
WhatA2diabetesA2drugA2classA2isA2atA2riskA2forA2hypoglycemia?

HowA2canA2thisA2beA2treated?A2-A2Ans--Sulfonylureas!A2

Glimepiride

CanA2alsoA2causeA2weightA2gain

TX:
Octreotide

WhatA2isA2MOAA2forA2Metformin?A2-A2Ans--BiguanideA2drugA2class

DecreasesA2hepaticA2glucogenesis

DiarrheaA2isA2sideA2effect

Don'tA2useA2inA2renalA2failure

WhatA2testA2canA2helpA2toA2determineA2ifA2aA2patientA2isA2surreptitiouslyA2self-
administeringA2insulin?A2-A2Ans--CA2peptideA2level:
Low

InsulinA2level:
A2
High

A2 isA2diagnosticA2forA2factitiousA2hypoglycemia!

WhatA2medicationsA2areA2bestA2forA2loweringA2triglyercides?

WhatA2medicationsA2areA2bestA2forA2loweringA2LDL?

WhatA2medicationsA2areA2bestA2forA2increasingA2HDL?

GoalsA2forA2allA2ofA2these?A2-A2Ans--Triglycerides:
BestA2loweredA2viaA2FIBRATES

LDL:
BestA2loweredA2viaA2STATINS

HDL:

,BestA2increasedA2viaA2NIACINA2(Flushing,A2PruritisA2SE)
ExerciseA2alsoA2increasesA2HDL

Goals:
Triglycerides-->A2<150
LDL-->A2<70
HDLA2-->A2>40

WhatA2isA2theA2criteriaA2forA2diagnosingA2DiabetesA2I?

MOA?

Tx?A2-A2Ans--FastingA2Glucose:
A2>126A2onA22A2separateA2occasionsA2

RandomA2Glucose:
>200

GlucoseA2ChallengeA275A2mg:
>200A22A2hoursA2postA2challenge

AlC:
>6.5%

MOA:
AutoimmuneA2DestructionA2ofA2PancreaticA2ß-cellsA2(isletsA2ofA2LangerhansA2beta-
cells)A2causingA2decreasedA2insulinA2+A2increasedA2glucose

Tx:
Insulin

WhatA2isA2preA2diabetesA2Alc?A2-A2Ans--5.7-6.4%

WhichA2ofA2theA2followingA2isA2theA2recommendedA2treatmentA2forA2aA2pituitaryA2adenoma
A2>1A2cmA2inA2size?A2-A2Ans-->A21cmA2orA2compressingA2opticA2chiasmA2PituitaryA2tumors:
SurgicalA2transphenoidalA2(hardy)A2resectionA2isA2treatmentA2ofA2choice!

RadiationA2therapy:
UsedA2inA2olderA2adultsA2thatA2cannotA2haveA2surgery

DopamineA2Agonists:
UsedA2inA2microA2tumorsA2orA2prolactinomasA2toA2reduceA2size/symptoms

WhatA2structureA2isA2commonlyA2compressedA2andA2affectsA2visionA2inA2thoseA2withA2aA2p
ituitaryA2adenoma?A2-A2Ans--OpticA2Chiasm!

, WhatA2presentsA2withA2bitemporalA2hemianopia?

Tx?A2-A2Ans--PituitaryA2tumorA2compressingA2OpticA2Chiasm!

Tx:
TranssphenoidalA2surgicalA2resection

WhatA2presentsA2withA2amenorrhea,A2galactorrhea,A2infertility?

Tx?A2-A2Ans--Prolactinoma

MostA2commonA2PituitaryA2Tumor!

Tx:
DopamineA2AgonistsA2
Bromocriptine,A2Cabergoline

WhatA2presentsA2withA2GigantismA2inA2childrenA2andA2AcromegalyA2inA2adults?A2-A2Ans--
PituitaryA2tumorA2hyperA2secretingA2GH!

WhatA2isA2mostA2commonA2complicationA2seenA2withA2pituitaryA2tumors?A2-A2Ans--
BitemporalA2Hemianopia

Meaning:
PartialA2BlindnessA2whereA2visionA2isA2MissingA2inA2theA2OuterA2HalfA2ofA2BothA2theA2Right
A2andA2LeftA2VisualA2Field.

WhatA2labsA2areA2expectedA2withA2TSHA2producingA2pituitaryA2adenoma?A2-A2Ans--
ElevatedA2TSH,A2HighA2T3A2andA2HighA2T4

ALLA2elevated!

WhatA2thyroidA2disorderA2isA2definedA2byA2alteredA2mentalA2statusA2andA2decompensated
A2metabolicA2state?A2-A2Ans--MyxedemaA2Coma!

MostA2severeA2manifestationA2ofA2Hypothyroidism

WhatA2presentsA2withA2generalizedA2weakness,A2fatigue,A2facialA2swelling,A2constipation,
A2coldA2intolerance,A2weightA2gain,A2periorbitalA2edema,A2dryA2skinA2withA2coarse/
brittleA2hair,A2delayedA2DTR?

ExpectedA2labs?

MostA2commonA2manifestation?

Tx?A2-A2Ans--Hypothyroidism!

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Number of pages: 27
Written in: 2025/2026
Type: Exam (elaborations)
Contains: Questions & answers

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