NSG124 Pharmacology Exam #2 Questions with
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Terms in this set (55)
Antimicrobial/Antiinfective - Antibacterial
Therapy - Antifungal
- Antiviral
Types - Antiprotozal
Microbial susceptibility with special emphasis to
Antimicrobial/Antiinfective resistance.
Therapy
Clinical use of medication -- we don't treat just to
Two Principles treat, we have to identify what the organism is to deal
with it properly.
Identify organism -- culture bacteria
Drug sensitivity of organism
Antimicrobial/Antiinfective Host factors -- patient allergies, other
Therapy conditions/illnesses, liver functions, kidney functions,
etc.
Selection of Antimicrobial
Drug nay be ruled out due to:
- Allergy
- Inability to penetrate site of infection
- Patient variables
,Antimicrobial/Antiinfective Disruption - ie. destroy cell wall
Therapy
Inhibition - ie. suppress protein synthesis
Selective Toxicity
Based on mode of action:
Antimicrobial/Antiinfective - Bacteriostatic
Therapy - Bactericidal
Classification of Based on their spectrum of action:
Antibiotics - Narrow
- Broad
Inhibit bacterial cell wall synthesis.
Drugs that disrupt the cell membrane.
Bactericidal inhibitors of protein synthesis.
Antimicrobial/Antiinfective
Therapy Bacteriostatic inhibitors of protein synthesis.
Mechanism of Action Interfere with synthesis or integrity of bacterial DNA
and RNA.
Drugs that suppress viral replication.
Inhibiting synthesis of tetrahydrofolate.
Antimicrobial/Antiinfective Acquired - less susceptible overtime, multiple
Therapy organisms.
Drug Resistance Innate - natural inborn.
Excreted by penicillins and cephalosporins.
Antimicrobial/Antiinfective
Therapy Beta-lactam rings.
Beta-Lactmases Rendered ineffective by beta-lactamases resulting in
beta-lactam-resistant bacteria.
, Antimicrobial/Antiinfective Secondary infections that occur when normal flora in
Therapy the body are removed.
Superinfection
Surgery
Antimicrobial/Antiinfective Bacterial endocarditis
Therapy
Neutropenia
Reasons for Prophylactic
Other: foley catheters, PICC line, long term
attachments to body
Treatment of viral infection.
Treatment of fever unknown origin.
Antimicrobial/Antiinfective
Therapy
Improper dosage.
Misuse of Antibiotics
Unknown bacteria.
Omission for surgical drainage.
Antimicrobial/Antiinfective Clinical response
Therapy
Laboratory results
Monitoring Antimicrobial
Therapy
Symptoms: shortness of breath, hives, flushed skin,
Antimicrobial/Antiinfective
swollen lips and tongue, etc.
Therapy
Treatment: Maintain airway, epinephrine,
Anaphylactic Shock
antihistamines.
Correct Answers | Latest Update
Save
Terms in this set (55)
Antimicrobial/Antiinfective - Antibacterial
Therapy - Antifungal
- Antiviral
Types - Antiprotozal
Microbial susceptibility with special emphasis to
Antimicrobial/Antiinfective resistance.
Therapy
Clinical use of medication -- we don't treat just to
Two Principles treat, we have to identify what the organism is to deal
with it properly.
Identify organism -- culture bacteria
Drug sensitivity of organism
Antimicrobial/Antiinfective Host factors -- patient allergies, other
Therapy conditions/illnesses, liver functions, kidney functions,
etc.
Selection of Antimicrobial
Drug nay be ruled out due to:
- Allergy
- Inability to penetrate site of infection
- Patient variables
,Antimicrobial/Antiinfective Disruption - ie. destroy cell wall
Therapy
Inhibition - ie. suppress protein synthesis
Selective Toxicity
Based on mode of action:
Antimicrobial/Antiinfective - Bacteriostatic
Therapy - Bactericidal
Classification of Based on their spectrum of action:
Antibiotics - Narrow
- Broad
Inhibit bacterial cell wall synthesis.
Drugs that disrupt the cell membrane.
Bactericidal inhibitors of protein synthesis.
Antimicrobial/Antiinfective
Therapy Bacteriostatic inhibitors of protein synthesis.
Mechanism of Action Interfere with synthesis or integrity of bacterial DNA
and RNA.
Drugs that suppress viral replication.
Inhibiting synthesis of tetrahydrofolate.
Antimicrobial/Antiinfective Acquired - less susceptible overtime, multiple
Therapy organisms.
Drug Resistance Innate - natural inborn.
Excreted by penicillins and cephalosporins.
Antimicrobial/Antiinfective
Therapy Beta-lactam rings.
Beta-Lactmases Rendered ineffective by beta-lactamases resulting in
beta-lactam-resistant bacteria.
, Antimicrobial/Antiinfective Secondary infections that occur when normal flora in
Therapy the body are removed.
Superinfection
Surgery
Antimicrobial/Antiinfective Bacterial endocarditis
Therapy
Neutropenia
Reasons for Prophylactic
Other: foley catheters, PICC line, long term
attachments to body
Treatment of viral infection.
Treatment of fever unknown origin.
Antimicrobial/Antiinfective
Therapy
Improper dosage.
Misuse of Antibiotics
Unknown bacteria.
Omission for surgical drainage.
Antimicrobial/Antiinfective Clinical response
Therapy
Laboratory results
Monitoring Antimicrobial
Therapy
Symptoms: shortness of breath, hives, flushed skin,
Antimicrobial/Antiinfective
swollen lips and tongue, etc.
Therapy
Treatment: Maintain airway, epinephrine,
Anaphylactic Shock
antihistamines.
