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MMG 404 final questions with detailed answers graded A+ 2025/2026 passed

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MMG 404 final questions with detailed answers graded A+ 2025/2026 passed

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MMG 404 final questions with detailed
answers graded A+ 2025/2026 passed

globin’s have... - correct answer ✔✔8 alpha helices



globin’s bind to... - correct answer ✔✔heme cofactor which binds to oxygen



His92 - correct answer ✔✔critical for heme binding



Phe42 - correct answer ✔✔locks heme into specific pocket



hemoglobin structure - correct answer ✔✔heterotetramers containing 2 alpha globins and 2
beta globins



HbF - correct answer ✔✔fetal

2 alpha 2 gamma



HbA2 - correct answer ✔✔adult

2 alpha and ?



HbA - correct answer ✔✔adult

2 alpha 2 beta



beta globin genes - correct answer ✔✔HSA 11p

, alpha globin genes - correct answer ✔✔HSA 16p



which type of structure is strongest clue? - correct answer ✔✔primary



Hb (O2) - correct answer ✔✔transport



OI - correct answer ✔✔extracellular matrix



BRCA1/2 - correct answer ✔✔genome integrity



FHC - correct answer ✔✔metabolic receptors



CFTR - correct answer ✔✔ion transport



DMD - correct answer ✔✔cytoskeleton



retina - correct answer ✔✔extreme hyperoxia, limited cellular regeneration, metabolically
active (needs lots of oxygen)



heart muscle - correct answer ✔✔extreme energy requirement and burning, limited cellular
regeneration



neuron - correct answer ✔✔molecule trafficking, easy to "gum" up the machinery, limited
cellular regeneration



red blood cells - correct answer ✔✔carry O2, not clog veins, rapid turn over and renewal

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