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ANCC Test Review 2025 – Latest Exam Prep & Study Materials

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Prepare confidently for the ANCC Certification Exam with this fully updated 2025 Test Review & Study Materials. Designed for Nurse Practitioner students and ANCC board candidates, this resource provides exam-aligned review content, high-yield practice questions, and verified answers, helping you strengthen clinical reasoning, diagnostic skills, and evidence-based decision-making. This guide covers essential NP domains and provides structured content for efficient study and exam readiness, making it ideal for both comprehensive review and last-minute preparation. What’s Included ️ Latest 2025 ANCC exam-aligned review questions ️ Verified answers with clear rationales ️ Adult, pediatric, geriatric & women’s health topics ️ Acute & chronic condition management ️ Pharmacology & safe prescribing review ️ Health promotion, screening & preventive care ️ Professional role, ethics & scope of practice ️ Ideal for quizzes, midterms, finals, and board preparation Perfect For ANCC board exam candidates Nurse Practitioner (NP) students MSN & DNP NP programs Post-graduate NP board review Anyone seeking reliable, exam-aligned ANCC test prep materials This study guide helps you reinforce high-yield content, identify weak areas, and approach the ANCC exam with confidence.

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ANCC Test Review 2025 – Latest Exam Prep &
Study Materials
A patient with type1 diabetes mellitus who is NPH and regular insulin split dosing
present with complains of early morning rise finger-stick blood glucose. A review of an
at-home glucose test reveals increased morning levels. After an increase in the evening
insulin dose, the problem worsens. This is most likely an example of:

a) Insulin Resistance
b) Insulin Allergy
c) The Somogyi Effect
d) Hyperglycemia-induced hypoglycemia. - correct answera) The Somogyi Effect

A 25-years-old present with a chief complaint of decreased mobility and pain of the right
shoulder exacerbated by movements. The patient reports that he participated in
extensive house painting 24 hours prior to the onset of pain. He denies any trauma.
Passive ROM is intact. No redness or ecchymosis is present. What is the next step to
be taken in order to make a Diagnosis?

a) Palpate the structure around the shoulder
b) Obtain an MIR to evaluate the shoulder
c) Order and X-Ray of the shoulder
d) Request an EMG
Apply SOAPE - correct answera) Palpate the structure around the shoulder
Apply SOAPE

A 65 years-old male presents to his clinic complaining of increasing fatigue, dyspnea on
exertion ,and ankle edema during the day. He has a history of mild hypertension, for
which he saw his physician years ago. The physician advised the patient to decrease
his salt intake .On physician examination the patient is tachycardia positive for jugular
venous distension, and positive for S3 with a systolic murmur chest X-ray reveals
cardiomegaly with vascular redistribution .The nurse practitioner diagnosis is :

a) Myocardial infarction
b) Pneumonia
c) Congestive heart failure
d) Pleural effusion - correct answerc) Congestive heart failure

A 67-year old patient with type 2 DM, congestive heart failure (CHF), and a mild artery
disease is currently taking daily hydrochlorothiazide 25 mg daily, glipizide 10 mg daily;
and atorvastatin (Lipitor), 20 mg h.s. Which of the following is an accurate statement
regarding this regimen?

,a) The glipizide will increase the risk of potassium depletion....
b) The digoxin will increase the risk of hypoglycemia.
c) The hydrochlorothiazide will predispose the patient to digoxin toxicity
d) The atorvastin will worsen the diabetes - correct answerc) The hydrochlorothiazide
will predispose the patient to digoxin toxicity

A 14 year-old who fell on her outstretched hand complains of proximal forearm pain X-
ray reveals a positive fat pad sign ,and the fully extend the elbow. No definitive bony
changes are seen on X-ray. The most likely working diagnosis is:

a) Upper extremely sprain.
b) Lateral epiconditis.
c) Radial head fracture
d) Olecranon bursitis - correct answerc) Radial head fracture

A 17 year-old female is suspected to have a Polycystic Ovary Syndrome. In addition to
testosterone the most appropriate diagnostic test will be:

a) BUN, creatinine, electrolytes, and denydroeplandrosterone (DHEA).
b) Complete blood count (BUN) ,creatinine and estrone
c) Fasting blood sugar(FBS) ,CBC, BUN and sex hormone binding globuline
d) Follicle stimulating hormone (FSH) luteinizing hormone, prolactin, and thyroid
stimulating hormone (TSH) - correct answerd) Follicle stimulating hormone (FSH)
luteinizing hormone, prolactin, and thyroid stimulating hormone (TSH)

To assess spinal function at S1-level, which deep tendon reflex should be tested?

a) Achilles
b) Cremasteric
c) Anal wink
d) Patelar - correct answera) Achilles

A 20 year-old male present with a month history of a "bump on my testicle." He reports
being sexually active, with frequent intercourse with multiple partners, which condition
should be suspected?

a) Cancer of testicles
b) Torsion of the testicles
c) Acute epididymitis
d) Gonorrhea - correct answera) Cancer of testicles

An 88 year-old male presents with concerns about memory loss .He feels good, takes
aspirin daily ,and has no chronic diseases ,he drives his own car ,and manages his
financial affairs .To evaluate his memory ,which of the fallowing tests would you
choose?

,a) Folstein Mini- Mental-State Examination.
b) Geriatric Depression Scale
c) Minnesota Multiphasic personality inventory
d) Myers -Briggs Test - correct answera) Folstein Mini- Mental-State Examination

Nonviral Microorganisms most frequently found to cause acute sinusitis are:

a) Streptococcus pneumonie and Haemophilus influenzae
b) Streptococcus pneumonie and staphylococcus aureus
c) Staphylococcus aureus and Pseudomonas aeruginosa
d) Streptococcus pneumonie and Pseudomonas aeruginosa - correct answera)
Streptococcus pneumonie and Haemophilus influenzae

A 65-year old female presents with shoulder and pelvic girdle pain for the past 6 months
.She reports recent unintentional weigh loss. On physical examination, there is pain on
ROM with no weakness noted. Laboratory studies show low hemoglobin and elevated
sedimentation rate.Which of the fallowing is the most likely diagnosis?

a) Polymyosistis
b) Osteoarthritis
c) Polymyalgia rheumatic
d) Fibromyalgia - correct answerc) Polymyalgia rheumatic

A 17 year-old female has never had her menses. She is at tanner stage III of sexual
development. Her physical and her weight is appropriate for her age and height. What is
the most likely diagnosis?

a) Secondary amenorrhea
b) Primary amenorrhea
c) Dysmenorrhea
d) Ovarian digenesis - correct answerb) Primary amenorrhea

A nurse practitioner is suturing a simple laceration on a 11-year old patient. The use of
lidocaine with epinephrine is not used in the following areas except the:

a) Scalp
b) Nose
c) Fingers
d) Earlobe - correct answera) Scalp

Which of the following is not an indication of preeclampsia?

a) Visual disturbance
b) Glycosuria
c) Edema of face and hands
d) Headaches - correct answerb) Glycosuria

, A 10- month-old presents with a rash, runny nose, and cough. Examination reveals a
cluster of tiny of white papules with an erythematous a buccal mucosa. What does this
suggest?

a) Scarlet Fever
b) Rubella
c) Erythema infectious
d) Measles - correct answerd) Measles
(Description of the Koplik's Spot")Small white round spots on the base of the buccal
mucosa by the rear molars)

Which of the following wet-mount results confirms a preliminary diagnosis of bacterial
vaginosis?

a) Squamous epithelial cells with stippling appearance and indistinct borders, no
lactobacillus rods, many white blood cells
b) Squamous epithelial cells with clear cytoplasm and distinct borders, many
lactobacillus rods, occasional white blood cells
c) Organism about the size of white blood cells with undulating flagellum, occasional
lactobacillus rods, many white blood cells
d) Hyphae and spores, few lactobacillus rods, occasional white blood cells. - correct
answera) Squamous epithelial cells with stippling appearance and indistinct borders, no
lactobacillus rods, many white blood cells

Which of the followings is typically a sign of acute appendicitis?

a) Periumbilical ecchymosis
b) Rebound tenderness at McBurneys point.
c) A negative Rovsing's sign
d) Pus and mucus in stool - correct answerb) Rebound tenderness at McBurneys point

Which of the following criteria differentiates a transient ischemic attack (TIA) from a
CVA?

a) Focal symptoms
b) Amnesia of incident
c) Slowness of onset
d) Absence of residual symptoms - correct answerd) Absence of residual symptoms
(TIA <24 hour recovery without neurologic deficit/ no brain damage)(CVA > 24 hours
with neurologic deficit)

Assessment findings that would support a diagnosis of mitral regurgitation include:

a) Diastolic murmur with split S1
b) Loud high pitched pansystolic murmur

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