NURS 6630 Psychopharmacology Actual
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Serotonin regulates -Answer-Mood, emotion, feeding, and
reproductive behavior
This class of antidepressants binds to presynaptic SERT and
inhibits them from reuptake of serotonin to increase levels in the
synaptic cleft to bind with postsysnaptic 5HT2 receptors -Answer-
SSRIs
First line therapy for MDD due to milder side effect profiles -
Answer-SSRIs
Six Common SSRIs -Answer-citalopram, escitalopram, fluoxetine,
fluvoxamine, sertraline, paroxetine
Onset of therapeutic benefit from SSRIs -Answer-4-6 weeks
In addition to MDD, SSRIs also treat -Answer-Chronic Anxiety,
PTSD, OCD, and eating disorders (bulimia)
Five Common side effects of SSRIs include -Answer-Anxiety,
insomnia, GI distress, sexual dysfunction (ED), SIADH
,Severe side effect of SSRIs in children/adolescents under age 25
years old -Answer-suicidal ideation
Life threatening adverse effect of SSRIs, especially when used in
combination with other serotonergic drugs (SNRIs, TCAs, MAOIs,
etc.) -Answer-Serotonin Syndrome
Excess accumulation of serotonin resulting in overstimulation of
the nervous system -Answer-Serotonin Syndrome
Seven symptoms of Serotonin Syndrome -Answer-Flushing,
hyperthermia, agitation, muscle rigidity, seizure, coma,
HYPERreflexia
The treatment for serotonin syndrome -Answer-Cyproheptadine
(5-HT2 receptor antagonist)
Cyproheptadine treats serotonin syndrome by -Answer-blocking
5-HT2 receptors (serotonin antagonist)
When SSRIs or SNRIs are stopped abruptly, common symptoms
of withdrawal include -Answer-Irritability, headaches, and
insomnia
Medicine specific side effect of citalopram -Answer-Prolonged QT
interval (normal=0.4.-0.44 seconds)
This SSRI is pregnancy category D due to associations with
congenital heart defects -Answer-Paroxetine
, All SSRIs but paroxetine (D) are pregnancy category -Answer-C
Three SSRIs that are inhibitors of Cytochrome P450 enzymes -
Answer-fluoxetine, fluvoxamine, and paroxetine
Five common SNRIs include -Answer-duloxetine, venlafaxine,
desvenlafaxine, milnacipran, levomilnacipran
This antidepressant class of medications works by binding to
presynaptic SERT and NET to inhibit them from reuptake of
serotonin and norepinephrine to increase their levels in the
synaptic cleft -Answer-SNRIs
In addition to MDD SNRIs treat -Answer-Anxiety and neuropathic
pain (peripheral neuropathy)
Medication specific indications of duloxetine: -Answer-urinary
incontinence and Fibromyalgia
Medication specific indications of venlafaxine: -Answer-social
anxiety, panic disorders, PTSD, OCD, postmenopausal hot
flashes
Six common side effects of SNRIs include: -Answer-Insomnia,
nausea, sexual dysfunction, hypertension, sweating, headaches
Severe side effect of SNRIs in children/adolescents under age 25
years old: -Answer-suicidal ideation
Exam 2026 NURS6630 Exam Latest
Update 2026 Questions and Correct
Answers Rated A+
Serotonin regulates -Answer-Mood, emotion, feeding, and
reproductive behavior
This class of antidepressants binds to presynaptic SERT and
inhibits them from reuptake of serotonin to increase levels in the
synaptic cleft to bind with postsysnaptic 5HT2 receptors -Answer-
SSRIs
First line therapy for MDD due to milder side effect profiles -
Answer-SSRIs
Six Common SSRIs -Answer-citalopram, escitalopram, fluoxetine,
fluvoxamine, sertraline, paroxetine
Onset of therapeutic benefit from SSRIs -Answer-4-6 weeks
In addition to MDD, SSRIs also treat -Answer-Chronic Anxiety,
PTSD, OCD, and eating disorders (bulimia)
Five Common side effects of SSRIs include -Answer-Anxiety,
insomnia, GI distress, sexual dysfunction (ED), SIADH
,Severe side effect of SSRIs in children/adolescents under age 25
years old -Answer-suicidal ideation
Life threatening adverse effect of SSRIs, especially when used in
combination with other serotonergic drugs (SNRIs, TCAs, MAOIs,
etc.) -Answer-Serotonin Syndrome
Excess accumulation of serotonin resulting in overstimulation of
the nervous system -Answer-Serotonin Syndrome
Seven symptoms of Serotonin Syndrome -Answer-Flushing,
hyperthermia, agitation, muscle rigidity, seizure, coma,
HYPERreflexia
The treatment for serotonin syndrome -Answer-Cyproheptadine
(5-HT2 receptor antagonist)
Cyproheptadine treats serotonin syndrome by -Answer-blocking
5-HT2 receptors (serotonin antagonist)
When SSRIs or SNRIs are stopped abruptly, common symptoms
of withdrawal include -Answer-Irritability, headaches, and
insomnia
Medicine specific side effect of citalopram -Answer-Prolonged QT
interval (normal=0.4.-0.44 seconds)
This SSRI is pregnancy category D due to associations with
congenital heart defects -Answer-Paroxetine
, All SSRIs but paroxetine (D) are pregnancy category -Answer-C
Three SSRIs that are inhibitors of Cytochrome P450 enzymes -
Answer-fluoxetine, fluvoxamine, and paroxetine
Five common SNRIs include -Answer-duloxetine, venlafaxine,
desvenlafaxine, milnacipran, levomilnacipran
This antidepressant class of medications works by binding to
presynaptic SERT and NET to inhibit them from reuptake of
serotonin and norepinephrine to increase their levels in the
synaptic cleft -Answer-SNRIs
In addition to MDD SNRIs treat -Answer-Anxiety and neuropathic
pain (peripheral neuropathy)
Medication specific indications of duloxetine: -Answer-urinary
incontinence and Fibromyalgia
Medication specific indications of venlafaxine: -Answer-social
anxiety, panic disorders, PTSD, OCD, postmenopausal hot
flashes
Six common side effects of SNRIs include: -Answer-Insomnia,
nausea, sexual dysfunction, hypertension, sweating, headaches
Severe side effect of SNRIs in children/adolescents under age 25
years old: -Answer-suicidal ideation
