GNUR 294 EXAM III- ANS & Cardiovasuclar | RATED 100%

GNUR 294 EXAM III Autonomic Nervous System • Focus on the sympathetic nervous system • PNS does the opposite of the SNS • Adrenergic- adrenaline • Norepinephrine • Helps to bind with these receptors and make a response in the system • Alpha receptors and beta receptors • Almost al the drugs (from a cardiovascular standpoint) will effect these receptors i.e. beta 2- adrenergic agonists • Sympathetic- fight or flight • All of these things that occur when NE is released and binds with the adrenergic receptors and all the adrenaline will be released • 1. The heart rate will go up- higher rate to support the oxygen needs • 2. Blood pressure goes up • 3. Bronchioles are going to dilate- deeper breaths and more oxygen • 4. Glucose released by the liver (stored as glycogen in the liver) • Because of all the blood is being shunted to the main organs, the organs that don’t really make a difference all will be stopped i.e. digesting food • Patients who have an increased heart rate or BP or extra myocardial oxygen demands b/c of blocked vessels are going to need this processed blocked from happening • If someone is critically ill and dying going to give them synthetic versions of these drugs to increase hear rate, BP, etc. • To be an agonist of these drugs is going to be in emergency situations • To be an antagonist will be given a lot • Alpha agonists and beta agonists • If I want to bind with someone need to see what these receptors do specifically • Alpha 1 receptors: o Causes vasoconstriction- usually more peripheral vasoconstriction o Pupillary dilatation • Beta 1 (cardiac receptors) o Increased heart rate, increased contractility- work on the heart itself o Decrease insulin release from pancrease and liver • Beta 2 o bronchodilation o Relaxation of the uterus