PHARMACOLOGY NURS 251 MODULE 6
PRACTICE EXAM 2026 QUESTIONS WITH
SOLUTIONS GRADED A+
◉ What is the therapeutic action of Hydrochlorothiazide (HCTZ)?
Answer: Inhibits reabsorption of sodium and chloride in the distal
renal tubules → increases excretion of sodium, chloride, and water.
◉ Hydrochlorothiazide (HCTZ) increases the excretion of _______ and
_______ by the kidneys. Answer: Sodium; chloride
◉ Which conditions are treated with Hydrochlorothiazide (HCTZ)?
Answer: Edema with heart failure, cirrhosis, hypertension, and renal
dysfunction
◉ True or False: Hydrochlorothiazide is used for acute renal failure.
Answer: False (It's contraindicated in severe renal disease)
◉ Which electrolyte imbalance is most commonly caused by
Hydrochlorothiazide? Answer: Hypokalemia
◉ Hypokalemia caused by Hydrochlorothiazide can result in what
potential cardiac complication? Answer: Dysrhythmias
,◉ True or False: Hydrochlorothiazide can cause orthostatic
hypotension due to increased fluid retention. Answer: False (It
causes hypotension due to fluid loss and volume depletion)
◉ Which adverse effect of Hydrochlorothiazide could increase fall
risk in older adults? Answer: Dizziness/vertigo and orthostatic
hypotension
◉ What are some signs of dehydration from Hydrochlorothiazide
use? Answer: Dry mouth, thirst, low urine output, weakness
◉ What metabolic side effect should be monitored in diabetic
patients taking Hydrochlorothiazide? Answer: Elevated blood
glucose (glucose abnormalities)
◉ True or False: Hydrochlorothiazide decreases uric acid excretion
and may worsen gout. Answer: True
◉ Hydrochlorothiazide is contraindicated in patients allergic to
_______ or _______. Answer: Thiazides; sulfa drugs
◉ Which autoimmune condition should be used with caution when
taking Hydrochlorothiazide? Answer: Systemic lupus erythematosus
(SLE)
, ◉ Hydrochlorothiazide (HCTZ) may cause increased _______ and
_______ excretion, leading to muscle cramps or spasms. Answer:
Water; electrolytes
◉ Which two electrolyte imbalances are commonly monitored with
Hydrochlorothiazide? Answer: Sodium and potassium
◉ True or False: Hydrochlorothiazide can cause
hyperparathyroidism and liver disease. Answer: False (It's used
cautiously in patients with these conditions, but it doesn't cause
them)
◉ What are common GI side effects of Hydrochlorothiazide?
Answer: Nausea, vomiting, diarrhea
◉ What is the expected outcome of Hydrochlorothiazide therapy?
Answer: Reduced edema and blood pressure, improved fluid balance
◉ True or False: Hydrochlorothiazide is safe for patients with severe
renal disease. Answer: False (It's contraindicated because it won't be
effective and can worsen kidney function)
PRACTICE EXAM 2026 QUESTIONS WITH
SOLUTIONS GRADED A+
◉ What is the therapeutic action of Hydrochlorothiazide (HCTZ)?
Answer: Inhibits reabsorption of sodium and chloride in the distal
renal tubules → increases excretion of sodium, chloride, and water.
◉ Hydrochlorothiazide (HCTZ) increases the excretion of _______ and
_______ by the kidneys. Answer: Sodium; chloride
◉ Which conditions are treated with Hydrochlorothiazide (HCTZ)?
Answer: Edema with heart failure, cirrhosis, hypertension, and renal
dysfunction
◉ True or False: Hydrochlorothiazide is used for acute renal failure.
Answer: False (It's contraindicated in severe renal disease)
◉ Which electrolyte imbalance is most commonly caused by
Hydrochlorothiazide? Answer: Hypokalemia
◉ Hypokalemia caused by Hydrochlorothiazide can result in what
potential cardiac complication? Answer: Dysrhythmias
,◉ True or False: Hydrochlorothiazide can cause orthostatic
hypotension due to increased fluid retention. Answer: False (It
causes hypotension due to fluid loss and volume depletion)
◉ Which adverse effect of Hydrochlorothiazide could increase fall
risk in older adults? Answer: Dizziness/vertigo and orthostatic
hypotension
◉ What are some signs of dehydration from Hydrochlorothiazide
use? Answer: Dry mouth, thirst, low urine output, weakness
◉ What metabolic side effect should be monitored in diabetic
patients taking Hydrochlorothiazide? Answer: Elevated blood
glucose (glucose abnormalities)
◉ True or False: Hydrochlorothiazide decreases uric acid excretion
and may worsen gout. Answer: True
◉ Hydrochlorothiazide is contraindicated in patients allergic to
_______ or _______. Answer: Thiazides; sulfa drugs
◉ Which autoimmune condition should be used with caution when
taking Hydrochlorothiazide? Answer: Systemic lupus erythematosus
(SLE)
, ◉ Hydrochlorothiazide (HCTZ) may cause increased _______ and
_______ excretion, leading to muscle cramps or spasms. Answer:
Water; electrolytes
◉ Which two electrolyte imbalances are commonly monitored with
Hydrochlorothiazide? Answer: Sodium and potassium
◉ True or False: Hydrochlorothiazide can cause
hyperparathyroidism and liver disease. Answer: False (It's used
cautiously in patients with these conditions, but it doesn't cause
them)
◉ What are common GI side effects of Hydrochlorothiazide?
Answer: Nausea, vomiting, diarrhea
◉ What is the expected outcome of Hydrochlorothiazide therapy?
Answer: Reduced edema and blood pressure, improved fluid balance
◉ True or False: Hydrochlorothiazide is safe for patients with severe
renal disease. Answer: False (It's contraindicated because it won't be
effective and can worsen kidney function)
