IMMUNOLOGY KUBY - EXAM 3
QUESTIONS AND ANSWERS
CTLs mediate a powerful and lethal immune response to infected host cells. Which of
the following steps is *NOT involved with CTL activation and function*? - Correct
Answers -*Histamine is released* from cytoplasmic granules recruiting macrophages to
the site in infection
Which of the following factors is thought to *induce expression of Blimp-1*? - Correct
Answers -*IRF-4*
*Peyer's patches* and lymphoid follicles are components of the: - Correct Answers -
*GALT*
Activation of a *naive T cell by the pAPC* will result in: - Correct Answers -*Cell
proliferation and cell differentiation*
The *first immunoglobulin isotype* produced during the course of a primary immune
response contains which of the following heavy chains? - Correct Answers -*M*
Which helper T cell subset is primarily involved in *regulating immunity against
intracellular pathogens*? - Correct Answers -*Th1*
*CD4+ T cells* recognize antigen on: - Correct Answers -*MHC class II* molecules
AID converts cytosine into which of the following bases? - Correct Answers -*Uracil*
Which immunoglobulin isotype *CANNOT be produced by memory B cells that have
undergone CSR*? - Correct Answers -*IgM*
A naive T cell refers to a T cell that: - Correct Answers -Has not yet encountered its
antigen
Superantigens differ from regular peptide antigens because they: - Correct Answers -
*All of the Above*
Bind outside the peptide-binding groove, activate a larger proportion of T cells, interact
with the V beta domain of the TCR, and can result in toxic shock
An antigen that activates a B cell by binding *both the BCR and PRR without T cell
help* is called: - Correct Answers -*TI-1*
QUESTIONS AND ANSWERS
CTLs mediate a powerful and lethal immune response to infected host cells. Which of
the following steps is *NOT involved with CTL activation and function*? - Correct
Answers -*Histamine is released* from cytoplasmic granules recruiting macrophages to
the site in infection
Which of the following factors is thought to *induce expression of Blimp-1*? - Correct
Answers -*IRF-4*
*Peyer's patches* and lymphoid follicles are components of the: - Correct Answers -
*GALT*
Activation of a *naive T cell by the pAPC* will result in: - Correct Answers -*Cell
proliferation and cell differentiation*
The *first immunoglobulin isotype* produced during the course of a primary immune
response contains which of the following heavy chains? - Correct Answers -*M*
Which helper T cell subset is primarily involved in *regulating immunity against
intracellular pathogens*? - Correct Answers -*Th1*
*CD4+ T cells* recognize antigen on: - Correct Answers -*MHC class II* molecules
AID converts cytosine into which of the following bases? - Correct Answers -*Uracil*
Which immunoglobulin isotype *CANNOT be produced by memory B cells that have
undergone CSR*? - Correct Answers -*IgM*
A naive T cell refers to a T cell that: - Correct Answers -Has not yet encountered its
antigen
Superantigens differ from regular peptide antigens because they: - Correct Answers -
*All of the Above*
Bind outside the peptide-binding groove, activate a larger proportion of T cells, interact
with the V beta domain of the TCR, and can result in toxic shock
An antigen that activates a B cell by binding *both the BCR and PRR without T cell
help* is called: - Correct Answers -*TI-1*
