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BIO 1301 FINAL EXAM QUESTIONS AND VERIFIED ANSWERS

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BIO 1301 FINAL EXAM QUESTIONS AND VERIFIED ANSWERS

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An unprocessed pre-mRNA has the following structure.
Which of the following is not a possible size (in bp) of the mature mRNA?


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205bp

,Bacterial transformation is a major concern in many medical settings. Why might
health care providers be concerned?


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Pathogenic bacteria could introduce disease-causing genes in non-
pathogenic bacteria.
Antibiotic resistance genes could be introduced to new bacteria to create
"superbugs."
Bacteriophages could spread DNA encoding toxins to new bacteria.




The ABO blood groups in humans are expressed as the IA, IB, and i alleles. The IA
allele encodes the A blood group antigen, IB encodes B, and i encodes O. Both A and
B are dominant to O. If a heterozygous blood type A parent (IAi) and a heterozygous
blood type B parent (IBi) mate, one quarter of their offspring will have AB blood type
(IAIB) in which both antigens are expressed equally. Therefore, ABO blood groups are
an example of:


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multiple alleles and codominance




In which direction does DNA replication take place?


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5'-3

,In a mating between two individuals that are heterozygous for a recessive lethal allele
that is expressed in utero, what genotypic ratio (homozygous
dominant:heterozygous:homozygous recessive) would you expect to observe in the
offspring?


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1:2:0




The binding of ________ is required for transcription to start.


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RNA polymerase




Which molecule is a Cdk inhibitor that is controlled by p53?


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p21




A diploid cell has_______ the number of chromosomes as a haploid cell.


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, twice




A scientist randomly mutates the DNA of a bacterium. She then sequences the
bacterium's daughter cells, and finds that the daughters have many errors in their
replicated DNA. The parent bacterium likely acquired a mutation in which enzyme?


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DNA pol II




If the allele encoding polydactyly (six fingers) is dominant why do most people have
five fingers?


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The polydactyl allele is very rare in the human population.




Targeted therapies are used in patients with a set gene expression pattern. A targeted
therapy that prevents the activation of the estrogen receptor in breast cancer would
be beneficial to which type of patient?


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patients with lots of the estrogen receptor expressed in their tumor

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