FNP Test Questions – Latest 2025/2026 Exam
Prep & Practice Review
What is the first-line treatment for asthma?
A. Inhaled corticosteroids
B. Long-acting beta2-agonists
C. Leukotriene inhibitors
D. Short-acting beta2-agonists - correct answerA. Inhaled corticosteroids
A young adult patient comes in with diffused generalized abdominal pain. Which of the
following signs would support a diagnosis of appendicitis? Select all that apply:
A. Murphy's sign
B. Obturator sign
C. Turner's sign
D. Blumberg sign
E. Rovsing sign - correct answerB. Obturator sign
D. Blumberg sign
E. Rovsing sign
An adolescent male patient presents to the office with diffused hives and pruritus that
began suddenly this morning. His mother brings him into the clinic as it appears to be
getting worse. What would be the next most appropriate action by the nurse
practitioner?
A. Administer Epinephrine IM in the office
B. Prescribe Benadryl 50 mg PO BID until symptoms resolve
C. Educate the patient about avoiding triggers in the future
D. Assess the patient further - correct answerD. Assess the patient further
A 13 year old female patient was recently diagnosed at an outside facility with
pharyngitis and prescribe amoxicillin. A week after starting the antibiotics, the patient
develops an erythematous maculopapular rash with healthy skin intervening throughout.
What should you educate the mother about?
A. This is likely scarlatina and we need to start Keflex instead
B. This is a typical side effect of taking amoxicillin, and it will result with use of OTC
steroids
C. Sometimes this rash occurs when patients are given antibiotics for viral etiologies of
strep throat. It will resolve on its own
,D. This rash is known as scarlatina so I am going to refer you to the ED for further
treatment - correct answerC. Sometimes this rash occurs when patients are given
antibiotics for viral etiologies of strep throat. It will resolve on its own
When does scarlatina occur? - correct answerIf strep throat is caused by Group A
Streptococcus and it goes untreated, we have to worry about scarlet fever and dust,
scarlatina rash.
Scarlatina rash is sandpapery and bright red.
A middle-aged adult male smoker with COPD presents to the clinic complaining of
several days of fever, loss of appetite, coughing, and chest pain. The cough is
productive of purulent sputum. Physical examination reveals a temperature of 102.0ºF
(39.0ºC), pulse of 88, and respiratory rate of 24. The lung exam reveals crackles on the
lower right lobe and wheezing on the upper airways. Which of the following bacteria is
more likely to be the infectious agent?
A. Streptococcus pneumoniae and Mycoplasma pneumoniae
B. Staphylococcus aureus and Mycoplasma pneumoniae
C. Haemophilus influenzae and Streptococcus pneumoniae
D. Legionella pneumophilia and Haemophilus influenzae - correct answerC.
Haemophilus influenzae and Streptococcus pneumoniae
What is the preferred treatment for the above patient's condition?
A. Amoxicillin
B. Doxycycline
C. Amoxicillin-clavulanate plus a macrolide
D. Azithromycin plus a fluoroquinolone - correct answerC. Amoxicillin-clavulanate plus a
macrolide
Isoniazid therapy is associated with some possible adverse events. Which of the
following events can be minimized or prevented with simultaneous intake of pyridoxin?
A. Hepatic toxicity
B. Peripheral neuropathy
C. Urticaria
D. Nausea and vomiting - correct answerB. Peripheral neuropathy
Which of the following is a major risk factor for fatal asthma?
A. Exercising in cold weather
B. Smoking and vaping
C. Hospital admission in past year
D. Allergy to pet dander and dust mites - correct answerC. Hospital admission in past
year
,What is the preferred reliever medication for asthmatics according to the Global
Initiative for Asthma (GINA, 2020) treatment guidelines?
A. Low-dose ICS with formoterol
B. SABA
C. LABA
D. Leukotriene receptor agonists - correct answerA. Low-dose ICS with formoterol
What type of electrolyte should an individual with primary hypertension increase in their
diet?
A. Calcium
B. Chloride
C. Potassium
D. Sodium - correct answerC. Potassium
After anti-hypertensive therapy is initiated, when should a patient's blood pressure be
rechecked?
A. 1 month
B. 2 months
C. 3 months
D. 4 months - correct answerA. 1 month
A 73-year-old male who is a smoker has a BMI of 28 and his newly diagnosed with
primary hypertension. He has a history of emphysema and second-degree AV block.
His blood pressure from the previous visit is 145/80 mmHg. During the current visit, his
blood pressure is 155/80 mmHg. What is the next step?
A. Start patient on atenolol 50 mg once a day and reassess in three months
B. Start patient on felodipine 2.5 mg once a day and reassess in two months
C. Start patient on chlorthalidone 12.5 mg daily and reassess in one month
D. No medication is needed at this time - correct answerC. Start patient on
chlorthalidone 12.5 mg daily and reassess in one month
All of the following ethnic groups are at higher risk for heart disease, except:
A. Mexican Americans
B. African-Americans
C. East Asians
D. Europeans - correct answerD. Europeans
What is the most common cause of death for people with DM?
A. Unintentional injuries or accidents
, B. Pancreatic cancer
C. Heart disease
D. Hypoglycemia - correct answerC. Heart disease
The best screening test for both hyperthyroidism and hypothyroidism is:
A. Free T4 (thyroxine)
B. Thyroid stimulating hormone
C. Thyroid profile
D. Palpation of the thyroid gland - correct answerB. Thyroid stimulating hormone
A male patient has type two diabetes mellitus and a " sensitive stomach". Which
medication is least likely to cause him gastrointestinal distress?
A. Naproxen sodium
B. Aspirin
C. Erythromycin
D. Sucralfate - correct answerD. Sucralfate
An obese Asian patient with a BMI of 33 complaints of fatigue and excessive thirst and
hunger. You suspect type two diabetes mellitus. Initial testing to confirm diagnosis can
include:
A. Fasting plasma glucose level
B. Glycated hemoglobin level (A1C)
C. Oral glucose tolerance testing
D. All of the above - correct answerD. All of the above
Which one of the following findings is associated with diabetic retinopathy?
A. AV nicking
B. Copper wire arterioles
C. Flame shaped hemorrhages
D. Microaneurysms - correct answerD. Microaneurysms
A 30 year old woman with type two diabetes uses regular and intermediate acting
insulin in the morning and evening. She denies changes in her diet or any illness, but
she recently started attending aerobic classes in the afternoon. Our fasting blood
glucose level before breakfast is now elevated. Which of the following is best
described?
A. Somogyi phenomenon
B. Dawn phenomenon
C. Raynaud's phenomenon
D. Insulin resistance - correct answerA. Somogyi phenomenon
Prep & Practice Review
What is the first-line treatment for asthma?
A. Inhaled corticosteroids
B. Long-acting beta2-agonists
C. Leukotriene inhibitors
D. Short-acting beta2-agonists - correct answerA. Inhaled corticosteroids
A young adult patient comes in with diffused generalized abdominal pain. Which of the
following signs would support a diagnosis of appendicitis? Select all that apply:
A. Murphy's sign
B. Obturator sign
C. Turner's sign
D. Blumberg sign
E. Rovsing sign - correct answerB. Obturator sign
D. Blumberg sign
E. Rovsing sign
An adolescent male patient presents to the office with diffused hives and pruritus that
began suddenly this morning. His mother brings him into the clinic as it appears to be
getting worse. What would be the next most appropriate action by the nurse
practitioner?
A. Administer Epinephrine IM in the office
B. Prescribe Benadryl 50 mg PO BID until symptoms resolve
C. Educate the patient about avoiding triggers in the future
D. Assess the patient further - correct answerD. Assess the patient further
A 13 year old female patient was recently diagnosed at an outside facility with
pharyngitis and prescribe amoxicillin. A week after starting the antibiotics, the patient
develops an erythematous maculopapular rash with healthy skin intervening throughout.
What should you educate the mother about?
A. This is likely scarlatina and we need to start Keflex instead
B. This is a typical side effect of taking amoxicillin, and it will result with use of OTC
steroids
C. Sometimes this rash occurs when patients are given antibiotics for viral etiologies of
strep throat. It will resolve on its own
,D. This rash is known as scarlatina so I am going to refer you to the ED for further
treatment - correct answerC. Sometimes this rash occurs when patients are given
antibiotics for viral etiologies of strep throat. It will resolve on its own
When does scarlatina occur? - correct answerIf strep throat is caused by Group A
Streptococcus and it goes untreated, we have to worry about scarlet fever and dust,
scarlatina rash.
Scarlatina rash is sandpapery and bright red.
A middle-aged adult male smoker with COPD presents to the clinic complaining of
several days of fever, loss of appetite, coughing, and chest pain. The cough is
productive of purulent sputum. Physical examination reveals a temperature of 102.0ºF
(39.0ºC), pulse of 88, and respiratory rate of 24. The lung exam reveals crackles on the
lower right lobe and wheezing on the upper airways. Which of the following bacteria is
more likely to be the infectious agent?
A. Streptococcus pneumoniae and Mycoplasma pneumoniae
B. Staphylococcus aureus and Mycoplasma pneumoniae
C. Haemophilus influenzae and Streptococcus pneumoniae
D. Legionella pneumophilia and Haemophilus influenzae - correct answerC.
Haemophilus influenzae and Streptococcus pneumoniae
What is the preferred treatment for the above patient's condition?
A. Amoxicillin
B. Doxycycline
C. Amoxicillin-clavulanate plus a macrolide
D. Azithromycin plus a fluoroquinolone - correct answerC. Amoxicillin-clavulanate plus a
macrolide
Isoniazid therapy is associated with some possible adverse events. Which of the
following events can be minimized or prevented with simultaneous intake of pyridoxin?
A. Hepatic toxicity
B. Peripheral neuropathy
C. Urticaria
D. Nausea and vomiting - correct answerB. Peripheral neuropathy
Which of the following is a major risk factor for fatal asthma?
A. Exercising in cold weather
B. Smoking and vaping
C. Hospital admission in past year
D. Allergy to pet dander and dust mites - correct answerC. Hospital admission in past
year
,What is the preferred reliever medication for asthmatics according to the Global
Initiative for Asthma (GINA, 2020) treatment guidelines?
A. Low-dose ICS with formoterol
B. SABA
C. LABA
D. Leukotriene receptor agonists - correct answerA. Low-dose ICS with formoterol
What type of electrolyte should an individual with primary hypertension increase in their
diet?
A. Calcium
B. Chloride
C. Potassium
D. Sodium - correct answerC. Potassium
After anti-hypertensive therapy is initiated, when should a patient's blood pressure be
rechecked?
A. 1 month
B. 2 months
C. 3 months
D. 4 months - correct answerA. 1 month
A 73-year-old male who is a smoker has a BMI of 28 and his newly diagnosed with
primary hypertension. He has a history of emphysema and second-degree AV block.
His blood pressure from the previous visit is 145/80 mmHg. During the current visit, his
blood pressure is 155/80 mmHg. What is the next step?
A. Start patient on atenolol 50 mg once a day and reassess in three months
B. Start patient on felodipine 2.5 mg once a day and reassess in two months
C. Start patient on chlorthalidone 12.5 mg daily and reassess in one month
D. No medication is needed at this time - correct answerC. Start patient on
chlorthalidone 12.5 mg daily and reassess in one month
All of the following ethnic groups are at higher risk for heart disease, except:
A. Mexican Americans
B. African-Americans
C. East Asians
D. Europeans - correct answerD. Europeans
What is the most common cause of death for people with DM?
A. Unintentional injuries or accidents
, B. Pancreatic cancer
C. Heart disease
D. Hypoglycemia - correct answerC. Heart disease
The best screening test for both hyperthyroidism and hypothyroidism is:
A. Free T4 (thyroxine)
B. Thyroid stimulating hormone
C. Thyroid profile
D. Palpation of the thyroid gland - correct answerB. Thyroid stimulating hormone
A male patient has type two diabetes mellitus and a " sensitive stomach". Which
medication is least likely to cause him gastrointestinal distress?
A. Naproxen sodium
B. Aspirin
C. Erythromycin
D. Sucralfate - correct answerD. Sucralfate
An obese Asian patient with a BMI of 33 complaints of fatigue and excessive thirst and
hunger. You suspect type two diabetes mellitus. Initial testing to confirm diagnosis can
include:
A. Fasting plasma glucose level
B. Glycated hemoglobin level (A1C)
C. Oral glucose tolerance testing
D. All of the above - correct answerD. All of the above
Which one of the following findings is associated with diabetic retinopathy?
A. AV nicking
B. Copper wire arterioles
C. Flame shaped hemorrhages
D. Microaneurysms - correct answerD. Microaneurysms
A 30 year old woman with type two diabetes uses regular and intermediate acting
insulin in the morning and evening. She denies changes in her diet or any illness, but
she recently started attending aerobic classes in the afternoon. Our fasting blood
glucose level before breakfast is now elevated. Which of the following is best
described?
A. Somogyi phenomenon
B. Dawn phenomenon
C. Raynaud's phenomenon
D. Insulin resistance - correct answerA. Somogyi phenomenon
