MSCI 500 Quiz: Cancer Pharmacology (Score for this quiz: 39 out of 40) 2025/026 Liberty University

MSCI 500 Quiz: Cancer Pharmacology (Score for this quiz: 39 out of 40)
2025/026 Liberty University

Quiz: Cancer Pharmacology
Score for this quiz: 39 out of 40
Submitted Oct 1 at 3pm
This attempt took 28 minutes.

Question 1
1..75 pts
These anticancer drugs work by inhibiting DNA synthesis except;

L-Asparaginase


Question 2
1..75 pts
These are topoisomerase II inhibitors except;

Topotecan


Question 3
1..75 pts
Which of these cancer chemotherapeutic agents works by inhibiting protein
degradation

Bortezomib


Question 4
1..75 pts
The ratio of LD50 to ED50 of a drug is described as its;


Therapeutic index

, Question 5
1..75 pts
The reciprocal of the concentration of a drug required to inhibit 50% of its
target's activity when all possible ligand and substrate concentrations have
been controlled for is called;

Selectivity


Question 6
1..75 pts
In a breast cancer patient whose tumor cells express large amounts of
estrogen receptors and are therefore very sensitive to estradiol, which of
these drugs will be very effective in reducing plasma levels of estradiol and
consequently the breast tumor growth?

Letrozole




Question 7
pts
In a 55 year old female breast cancer patient whose tumor cells are estrogen
sensitive, which of the following chemotherapeutic agents is most likely to
control the breast tumor growth but predispose the patient to endometrial
cancer?

Tamoxifen




Question 8
pts
Which of these agents targets the tyrosine kinase domain of the fusion
protein formed from the Philadelphia chromosome and will be helpful in
chronic myelogenous leukemia?

Imatinib