TEST BANK For Basic and Clinical Pharmacology, 15th Edition by Bertram G. Katzung, Verified Chapters 1 - 66, Complete Newest Version

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BASIC AND CLINICAL PHARMACOLOGY 15TH EDITION K
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ATZUNG TREVOR TEST BANK
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INCLUSIVE OF CHAPTERS 1-66 COMPLETE WITH EXPLAINED ANSWERS
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Basic and Clinical Pharmacology 15th Edition Katzung Trevor Test Bank
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Chapter 1. Introduction: The Nature of Drugs & Drug Development & Regulation
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1.
A nurse working in radiology administers iodine to a patient who is
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@having a computed tomography (CT) scan. The nurse working on the
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oncology unit administers chemotherapy to patients who have cancer. A
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t the Public Health Department, a nurse administers a measles-mumps-
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rubella (MMR) vaccine to a 14-month-
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old child as a routine immunization. Which branch of pharmacology be
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st describes the actions of all three nurses?
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A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:

Pharmacology is the study of the biologic effects of chemicals. Nurses
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@are involved with clinical pharmacology or pharmacotherapeutics, whic
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h is a branch of pharmacology that deals with the uses of drugs to tre
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at, prevent, and diagnose disease. The radiology nurse is administering
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@a drug to help diagnose a disease. The oncology nurse is administerin
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g a drug to help treat a disease. Pharmacoeconomics includes any costs
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involved in drug therapy.
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Pharmacodynamics involves how a drug affects the body and pharmacoki x@ x@ x@ x@ x@ x@ x@ x@ x@


netics is how the body acts on the body.
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2.
When involved in phase III drug evaluation studies,
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x@ what responsibilities would the nurse have?
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A) Working with animals who are given experimental drugs
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B) Choosing appropriate patients to be involved in the drug study
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C) Monitoring and observing patients closely for adverse effects
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D) Conducting research to determine effectiveness of the drug
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Ans: C
Feedback:

Phase III studies involve use of a drug in a vast clinical population in
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@which patients are asked to record any symptoms they experience whil
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e taking the drugs. Nurses may be responsible for helping collect and
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analyze the information to be shared with the Food and Drug Administ
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ration (FDA) but would not conduct research independently because nu
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rses do not prescribe medications. Use of animals in drug testing is d
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one in the preclinical trials. Select patients who are involved in phase
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II studies to participate in studies where the participants have the disea
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se the drug is intended to treat. These patients are monitored closely f
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or drug action and adverse effects. Phase I studies involve healthy hu
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man volunteers who are usually paid for their participation. Nurses ma
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y observe for adverse effects and toxicity.
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3.
A physician has ordered intramuscular (IM) injections of morphine,
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a narcotic, every 4 hours as needed for pain in a motor vehicle accide
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nt victim. The nurse is aware this drug has a high abuse potential. Un
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der what category would morphine be classified?
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A) Schedule I x@




B) Schedule II x@




C) Schedule III x@




D) Schedule IV x@




Ans: B
Feedback:

Narcotics with a high abuse potential are classified as Schedule II dr
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ugs because of severe dependence liability. Schedule I drugs have hig
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h abuse potential and no accepted medical use. Schedule III drugs ha
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ve a lesser abuse potential than II and an accepted medical use. Sched
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ule IV drugs have low abuse potential and limited dependence liabilit
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y.
4.
What concept is considered when generic drugs are substituted for
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x@ brand name drugs? x@ x@




A) Bioavailability

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