MSN 671 NEI Global Video Questions
and Answers 100% Pass
Communication between human CNS neurons at synapses is: - CORRECT
ANSWER-Chemical
An example of volume neurotransmission is: - CORRECT ANSWER-Dopamine
in the prefrontal cortex
The direct role of transcription factors is to: - CORRECT ANSWER-Influence
gene expression
The term epigenetics refers to: - CORRECT ANSWER-A process determining
whether a given gene is expressed or silenced
Presynaptic reuptake transporters are a major method of inactivation for which of
the following? - CORRECT ANSWER-Serotonin and GABA
What is constitutive activity? - CORRECT ANSWER-Signal transduction when no
agonist or inverse agonist is bound to the receptor.
A partial agonist has what effect on neurotransmission? - CORRECT ANSWER-
Net agonism when neurotransmission is deficient.
Net antagonism when neurotransmission is excessive.
,Both of the above answers are correct
Agonists cause ligand-gated ion channels to: - CORRECT ANSWER-Open more
frequently
Which of the following is true? - CORRECT ANSWER-Both positive and
negative allosteric modulations are possible only in the presence of a
neurotransmitter
When voltage-sensitive sodium channels are open and activated, the flow of
sodium is: - CORRECT ANSWER-Into the neuron
Which of the following are involved in regulating neurotransmission via excitation-
secretion coupling? - CORRECT ANSWER-Both of these which are voltage-
sensitive sodium channels and voltage-sensitive calcium channels.
A 21-year-old man who has just been diagnosed with schizophrenia presents with
his parents. He speaks with a reserved and simple language processing style; he is
able to understand and relate to simple questions but seems to get lost when the
pace of the conversation between the clinician and parents accelerates. when
reviewing the patient's history, what pattern of cognitive functioning prior to
psychosis onset would you be most likely to find? - CORRECT ANSWER-
Impaired cognitive functioning premorbidly with further decline during the
prodromal phase.
Dopamine (DA) receptors can be categorized as D1 like (D1 and D5 receptors)
and D2 like (D2, D3, and D4 receptors). What differentiates the two groups of
COPYRIGHT ALL RIGHTS RESERVED ©️ 2025
, receptors? - CORRECT ANSWER-D1-like receptors are excitatory and D2-like
receptors are inhibitory.
Symptoms of schizophrenia are hypothetically attributable to malfucntioning in
the: - CORRECT ANSWER-Mesocortical and mesolimbic pathways
For which set of disorders is psychosis considered an associated feature rather than
a defining feature for diagnosis? - CORRECT ANSWER-Bipolar mania,
Parkinson's disease.
The activation of N-methyl-d-aspartate (NMDA) receptors requires the presence
of: - CORRECT ANSWER-Glutamate and glycine.
A leading hypothesis of psychosis is: - CORRECT ANSWER-Hypofunctioning
NMDA receptors.
Dysfunction of NMDA-receptor containing synapses is hypothesized to lead to
excessive glutamate release in the ventral tegmental area. Downstream, this is
hypothesized to lead to what effects on dopamine (DA)? - CORRECT ANSWER-
Excessive DA release in the NA and reduced DA release in the PFC.
The neurodevelopmental hypothesis of schizophrenia centers heavily around the
idea that aberrant competitive elimination occurs. Competitive elimination is a
stage of neurodevelopment in which: - CORRECT ANSWER-Rarely used
synapses are pruned, while frequently used synapses are preserved.
and Answers 100% Pass
Communication between human CNS neurons at synapses is: - CORRECT
ANSWER-Chemical
An example of volume neurotransmission is: - CORRECT ANSWER-Dopamine
in the prefrontal cortex
The direct role of transcription factors is to: - CORRECT ANSWER-Influence
gene expression
The term epigenetics refers to: - CORRECT ANSWER-A process determining
whether a given gene is expressed or silenced
Presynaptic reuptake transporters are a major method of inactivation for which of
the following? - CORRECT ANSWER-Serotonin and GABA
What is constitutive activity? - CORRECT ANSWER-Signal transduction when no
agonist or inverse agonist is bound to the receptor.
A partial agonist has what effect on neurotransmission? - CORRECT ANSWER-
Net agonism when neurotransmission is deficient.
Net antagonism when neurotransmission is excessive.
,Both of the above answers are correct
Agonists cause ligand-gated ion channels to: - CORRECT ANSWER-Open more
frequently
Which of the following is true? - CORRECT ANSWER-Both positive and
negative allosteric modulations are possible only in the presence of a
neurotransmitter
When voltage-sensitive sodium channels are open and activated, the flow of
sodium is: - CORRECT ANSWER-Into the neuron
Which of the following are involved in regulating neurotransmission via excitation-
secretion coupling? - CORRECT ANSWER-Both of these which are voltage-
sensitive sodium channels and voltage-sensitive calcium channels.
A 21-year-old man who has just been diagnosed with schizophrenia presents with
his parents. He speaks with a reserved and simple language processing style; he is
able to understand and relate to simple questions but seems to get lost when the
pace of the conversation between the clinician and parents accelerates. when
reviewing the patient's history, what pattern of cognitive functioning prior to
psychosis onset would you be most likely to find? - CORRECT ANSWER-
Impaired cognitive functioning premorbidly with further decline during the
prodromal phase.
Dopamine (DA) receptors can be categorized as D1 like (D1 and D5 receptors)
and D2 like (D2, D3, and D4 receptors). What differentiates the two groups of
COPYRIGHT ALL RIGHTS RESERVED ©️ 2025
, receptors? - CORRECT ANSWER-D1-like receptors are excitatory and D2-like
receptors are inhibitory.
Symptoms of schizophrenia are hypothetically attributable to malfucntioning in
the: - CORRECT ANSWER-Mesocortical and mesolimbic pathways
For which set of disorders is psychosis considered an associated feature rather than
a defining feature for diagnosis? - CORRECT ANSWER-Bipolar mania,
Parkinson's disease.
The activation of N-methyl-d-aspartate (NMDA) receptors requires the presence
of: - CORRECT ANSWER-Glutamate and glycine.
A leading hypothesis of psychosis is: - CORRECT ANSWER-Hypofunctioning
NMDA receptors.
Dysfunction of NMDA-receptor containing synapses is hypothesized to lead to
excessive glutamate release in the ventral tegmental area. Downstream, this is
hypothesized to lead to what effects on dopamine (DA)? - CORRECT ANSWER-
Excessive DA release in the NA and reduced DA release in the PFC.
The neurodevelopmental hypothesis of schizophrenia centers heavily around the
idea that aberrant competitive elimination occurs. Competitive elimination is a
stage of neurodevelopment in which: - CORRECT ANSWER-Rarely used
synapses are pruned, while frequently used synapses are preserved.
