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NR546 Advanced Pharmacology: Psychopharmacology – Final Exam Study Guide Module 5-8

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This document provides a comprehensive Final Exam Study Guide for NR546/NR 546 Advanced Pharmacology: Psychopharmacology. It covers essential psychopharmacology concepts, including neurotransmitter pathways, psychotropic medication classes, mechanisms of action, clinical indications, side effects, contraindications, and advanced nursing considerations. Designed to support exam readiness, this guide offers a clear and structured review of all major topics required for successful performance in the course.

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Chamberlain College of Nursing

Final Exam Study Guide
Module 5: Treatment for Mood Disorders
Module 6: Treatments for Substance Use Disorders
Module 7: Treatments for ADHD & Sleep Disorders
Module 8: Treatments for Alzheimer’s disease and other
Dementias




Course: NR546/NR 546 Advanced
Pharmacology: Psychopharmacology

, Final Exam

Module 5: Treatment for Mood Disorders

Major Depressive Disorder (MDD):

• Review the monoamine hypothesis and its implications for prescribing, focusing on how this
theory informs the selection of antidepressants based on neurotransmitter targets and symptom
profiles
• SSRIs:
o Identify necessary screening prior to prescribing.
o Study age-related risks and which age group requires extra caution.
o Understand which SSRI has the least CYP interactions, best tolerance, and longest half-
life.
o Explore SSRIs associated with discontinuation syndrome, activation, or panic
exacerbation.
• Lithium Interactions:
o Know substances and medications that can affect lithium levels (cause increase or
decrease in lithium level).
• Serotonin Syndrome:
o Know symptoms and causes and what distinguishes serotonin syndrome from other
adverse effects.
• Pharmacological Adjuncts:
o Review medications used alongside SSRIs.
• Medication Comparisons:
o Differentiate between medications that exacerbate anxiety and those pharmacologically
similar to SSRIs and buspirone.

Monoamine Oxidase Inhibitors (MAOIs):

• Understand half-life, interactions, benefits, and adverse effects.

Bipolar Disorder:

• Review the half-life, interactions, and adverse effects of mood stabilizers. Know how half-life
influences dosing frequency and patient adherence to treatment plans.
• Explore side effects unique to this medication class and specific treatments for common adverse
reactions.

General Medication Knowledge:

• What medication should be avoided in clients with an eating disorder? Why?
• Review the mechanism of action (MOA), adverse reactions, indications, starting doses, and
necessary lab tests.
• Which medication has a risk priapism?
• Understand neurotransmitter actions beyond 5HT (such as norepinephrine, dopamine and GABA)
and how these subtypes influence treatment outcomes in anxiety and depression.

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