Complete Questions & Correct
Quiz_________________?
1-turn/2-turn joining rule (12/23 rule) -
Answer✅
signal sequences having 1- turn spacer can only join with sequences having 2-turn spacers
-ensures that gene segments are joined in the correct order
Quiz_________________?
Activation- induced cytidine deaminase (AID) -
Answer✅
involved in somatic hypermutation, an enzyme that converts cytosine to uracil which are
then replaced with non-template nucleotides
Quiz_________________?
Acute asthma is a type I response but can lead to chronic asthma and what type is chronic
and what cell mediates? -
Answer✅
Acute response in allergic asthma leads to Th2-mediated chronic inflammation of airways
1
, Crosslinking of specific IgE on mast cells by inhaled allergen triggers mast cell secretion of
inflammatory mediators
Result: Bronchial smooth muscle contraction w/increased mucus secretion -> airway
obstruction -> chronic asthma (Type IV)
Quiz_________________?
acute phase proteins -
Answer✅
produced in response to inflammatory cytokines; produced by hepatocytes in liver
Quiz_________________?
affinity -
Answer✅
the tightness of binding of an antibody binding site to an antigen
- antibodies produced by a memory response have a higher affinity than those in a primary
response
Quiz_________________?
affinity maturation -
Answer✅
as immune response proceeds, antibodies of higher affinity will be produced
Quiz_________________?
allelic exclusion -
Answer✅
2
, only one heavy chain and one light chain are produced in each B-cell
-rearranged H or L chain is expressed from only one chromosome
Quiz_________________?
Allergic Asthma -
Answer✅
Type I
Quiz_________________?
Allergic Conjunctivitis -
Answer✅
Type 1
Quiz_________________?
Allergic Rhinitis -
Answer✅
Type I
Quiz_________________?
Allergy -
Answer✅
Common environmental antigens that cause hypersensitivity reactions; nickel, plants,
perfumes are most common
3
, Quiz_________________?
alpha beta T cell surrogate chain -
Answer✅
pt-alpha (pre-t-cell receptor) which signals the cell to halt rearrangement of beta, gamma
and delta genes and begin to proliferate
Quiz_________________?
an individual's population of T cells -
Answer✅
many millions of different TCR, each defines a clone of T cells with a single AG- binding
specificity
Quiz_________________?
anergic T cells -
Answer✅
don't make IL-2 > no proliferation or differentiation, can never be stimulated to proliferate
or differentiate
Quiz_________________?
Angioedema -
Answer✅
Type I
Quiz_________________?
antibodies (Abs) -
4
Quiz_________________?
1-turn/2-turn joining rule (12/23 rule) -
Answer✅
signal sequences having 1- turn spacer can only join with sequences having 2-turn spacers
-ensures that gene segments are joined in the correct order
Quiz_________________?
Activation- induced cytidine deaminase (AID) -
Answer✅
involved in somatic hypermutation, an enzyme that converts cytosine to uracil which are
then replaced with non-template nucleotides
Quiz_________________?
Acute asthma is a type I response but can lead to chronic asthma and what type is chronic
and what cell mediates? -
Answer✅
Acute response in allergic asthma leads to Th2-mediated chronic inflammation of airways
1
, Crosslinking of specific IgE on mast cells by inhaled allergen triggers mast cell secretion of
inflammatory mediators
Result: Bronchial smooth muscle contraction w/increased mucus secretion -> airway
obstruction -> chronic asthma (Type IV)
Quiz_________________?
acute phase proteins -
Answer✅
produced in response to inflammatory cytokines; produced by hepatocytes in liver
Quiz_________________?
affinity -
Answer✅
the tightness of binding of an antibody binding site to an antigen
- antibodies produced by a memory response have a higher affinity than those in a primary
response
Quiz_________________?
affinity maturation -
Answer✅
as immune response proceeds, antibodies of higher affinity will be produced
Quiz_________________?
allelic exclusion -
Answer✅
2
, only one heavy chain and one light chain are produced in each B-cell
-rearranged H or L chain is expressed from only one chromosome
Quiz_________________?
Allergic Asthma -
Answer✅
Type I
Quiz_________________?
Allergic Conjunctivitis -
Answer✅
Type 1
Quiz_________________?
Allergic Rhinitis -
Answer✅
Type I
Quiz_________________?
Allergy -
Answer✅
Common environmental antigens that cause hypersensitivity reactions; nickel, plants,
perfumes are most common
3
, Quiz_________________?
alpha beta T cell surrogate chain -
Answer✅
pt-alpha (pre-t-cell receptor) which signals the cell to halt rearrangement of beta, gamma
and delta genes and begin to proliferate
Quiz_________________?
an individual's population of T cells -
Answer✅
many millions of different TCR, each defines a clone of T cells with a single AG- binding
specificity
Quiz_________________?
anergic T cells -
Answer✅
don't make IL-2 > no proliferation or differentiation, can never be stimulated to proliferate
or differentiate
Quiz_________________?
Angioedema -
Answer✅
Type I
Quiz_________________?
antibodies (Abs) -
4
