IMMUNOLOGY EXAM 5 WEIGEL |
COMPREHENSIVE PRACTICE
TEST |STUDY GUIDE NEWEST
ACTUAL QUESTIONS &
ANSWERS (A+ GUIDE
Quiz_________________?
Antigen binding (does the B cell take up the antigen, what is this called)
Binding of antigen sends a signal to the B cells' _________ to change _______________.
Yes the B cell takes up the ________ by internalizing Ag by
___________________________ which processes and presents it to
_______________ -
Answer✅
nucleus ; gene expression ; antigen ; receptor mediated endocytosis ; helper T-cells
Quiz_________________?
Are _______________________ in the gut destructive, phagocytic and able to secrete
inflammatory cytokines? -
Answer✅
phagocytic leukocytes ; Yes ; No
Quiz_________________?
1
, Are the classical and alternative pathways completely separate and if not which pathway
helps the other and with an increase in what? -
Answer✅
No ; Alternative can amplify classical with an increase in C3b on the pathogen surface
Quiz_________________?
Brambell receptors (FcRB or FcRn) - what do they do and, what are they used for? What do
they look like? How many are used in the transport of the antibody?
An ____________ that transports ______ across epithelia and has structure resembling
an ________________ molecules. IgG is actively transported from blood into extracellular
spaces by this Fc receptor present on _________________ cells. It has a similar structure
to MHC class I (α1 & α2 domains to bind the Fc regions of the Ab). _______ molecules of
FcRB bind to the Fc region of _____ IgG. -
Answer✅
Fc receptor ; IgG ; MHC class I ; endothelial ; Two ; one
Quiz_________________?
C3b and what is its main purpose- opsonin:
____________________, ____________ of large granular lymphocytes & phagocytes,
and it helps ______________ transport _______________________. -
Answer✅
Opsonization ; activation ; erythrocytes ; immune complexes
Quiz_________________?
Classical C3 convertase -
Answer✅
2
, C4b2a
Quiz_________________?
Cleavage steps in the classical complement cascade:
Activated ________ cleaves _____ into _____ & ______. Some ________ binds
covalently to microbial surface. Activated C1s also cleaves _____ into ______ & ____.
_____ binds covalently to the surface of ______, this forms the classical convertase
_________. This then cleaves _____ into _______ & ______ to make Classiscal ____
convertase, _________________ which will activate C5 and initiate MAC formation. C3b
then binds covalently to the microbial surface. -
Answer✅
C1s ; C4 ; C4a ; C4b ; C4b ; C2 ; C2a ; C2b ; C2a ; C4b ; C4b2a ; C3 ; C3a ; C3b ; C5 ;
C4b2a3b
Quiz_________________?
Complement activation: -
Answer✅
Complement Activation of the classical pathway
Quiz_________________?
CR1 binds to ________ -
Answer✅
C4B
Quiz_________________?
3
COMPREHENSIVE PRACTICE
TEST |STUDY GUIDE NEWEST
ACTUAL QUESTIONS &
ANSWERS (A+ GUIDE
Quiz_________________?
Antigen binding (does the B cell take up the antigen, what is this called)
Binding of antigen sends a signal to the B cells' _________ to change _______________.
Yes the B cell takes up the ________ by internalizing Ag by
___________________________ which processes and presents it to
_______________ -
Answer✅
nucleus ; gene expression ; antigen ; receptor mediated endocytosis ; helper T-cells
Quiz_________________?
Are _______________________ in the gut destructive, phagocytic and able to secrete
inflammatory cytokines? -
Answer✅
phagocytic leukocytes ; Yes ; No
Quiz_________________?
1
, Are the classical and alternative pathways completely separate and if not which pathway
helps the other and with an increase in what? -
Answer✅
No ; Alternative can amplify classical with an increase in C3b on the pathogen surface
Quiz_________________?
Brambell receptors (FcRB or FcRn) - what do they do and, what are they used for? What do
they look like? How many are used in the transport of the antibody?
An ____________ that transports ______ across epithelia and has structure resembling
an ________________ molecules. IgG is actively transported from blood into extracellular
spaces by this Fc receptor present on _________________ cells. It has a similar structure
to MHC class I (α1 & α2 domains to bind the Fc regions of the Ab). _______ molecules of
FcRB bind to the Fc region of _____ IgG. -
Answer✅
Fc receptor ; IgG ; MHC class I ; endothelial ; Two ; one
Quiz_________________?
C3b and what is its main purpose- opsonin:
____________________, ____________ of large granular lymphocytes & phagocytes,
and it helps ______________ transport _______________________. -
Answer✅
Opsonization ; activation ; erythrocytes ; immune complexes
Quiz_________________?
Classical C3 convertase -
Answer✅
2
, C4b2a
Quiz_________________?
Cleavage steps in the classical complement cascade:
Activated ________ cleaves _____ into _____ & ______. Some ________ binds
covalently to microbial surface. Activated C1s also cleaves _____ into ______ & ____.
_____ binds covalently to the surface of ______, this forms the classical convertase
_________. This then cleaves _____ into _______ & ______ to make Classiscal ____
convertase, _________________ which will activate C5 and initiate MAC formation. C3b
then binds covalently to the microbial surface. -
Answer✅
C1s ; C4 ; C4a ; C4b ; C4b ; C2 ; C2a ; C2b ; C2a ; C4b ; C4b2a ; C3 ; C3a ; C3b ; C5 ;
C4b2a3b
Quiz_________________?
Complement activation: -
Answer✅
Complement Activation of the classical pathway
Quiz_________________?
CR1 binds to ________ -
Answer✅
C4B
Quiz_________________?
3
