NURS 6630 PSYCHOPHARMACOLOGY
MIDTERM STUDY GUIDE EXAM [VERSION A &
B] NEWEST 2026 ACTUAL EXAM COMPLETE
QUESTIONS AND CORRECT DETAILED
ANSWERS (VERIFIED ANSWERS) |ALREADY
GRADED A+||BRAND NEW!!
(WALDEN UNIVERSITY)
Adverse effects of MAOIs include: - CORRECT ANSWER ✔✔- Serotonin
syndrome and hypertensive crisis
Before starting another antidepressant MAOIs should be stopped for at least: -
CORRECT ANSWER ✔✔- Two weeks (to allow for the body to replace MAO
enzymes so that serotonin syndrome does not occur)
Five main symptoms of hypertensive crisis: - CORRECT ANSWER ✔✔-
hyperthermia, hypertension, tachycardia, arrhythmias, agitation
Hypertensive crisis commonly occurs when people taking MAOIs consume foods
or drinks high in: - CORRECT ANSWER ✔✔- tyramine (cheese, wine, beer,
cured/smoked meats)
Foods and drinks rich in tyramine: - CORRECT ANSWER ✔✔- cheese, wine,
beer, cured/smoked meats
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,When uninhibited, these two enzymes are responsible for breaking down tyramine:
- CORRECT ANSWER ✔✔- MAO-A and MAO-B
When tyramine is not broken down, it increases the release of this
neurotransmitter, which causes hypertensive crisis: - CORRECT ANSWER ✔✔-
Norepinephrine
Due to its action as an adrenergic antagonist this drug is the treatment of
hypertensive crisis: - CORRECT ANSWER ✔✔- Phentolamine
TCAs are subdivided into these two groups: - CORRECT ANSWER ✔✔- Tertiary
TCAs and Secondary TCAs
Three Tertiary TCAs: - CORRECT ANSWER ✔✔- amitriptyline, imipramine,
clomipramine
Two Secondary TCAs: - CORRECT ANSWER ✔✔- desipramine, nortriptyline
Tertiary TCAs are non-selective and act on: - CORRECT ANSWER ✔✔-
Serotonin and Norephinephrine transporters (increase 5HT and NE)
Secondary TCAs are selective and act only on: - CORRECT ANSWER ✔✔-
Norepinephrine transporters (increase NE)
Therapeutic benefits from TCAs typically take approximately: - CORRECT
ANSWER ✔✔- 2-4 weeks
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, In addition to treatment of depression, other indications for TCAs include: -
CORRECT ANSWER ✔✔- Phobic disorders, chronic neuropathic pain, migraine
prophylaxis
Medication specific indication for clomipramine: - CORRECT ANSWER ✔✔-
OCD
Medication specific indication for imipramine: - CORRECT ANSWER ✔✔-
Nocturnal enuresis
In addition to SERTs and NETs, TCAs block (causes side effects): - CORRECT
ANSWER ✔✔- Histamine (H1) receptors, Muscarinic receptors, and Alpha 1
receptors
TCAs inhibitory effects on Histamine (H1) receptors results in this side effect: -
CORRECT ANSWER ✔✔- sedation
TCAs inhibitory effects on Muscarinic receptors results in this side effect profile: -
CORRECT ANSWER ✔✔- anticholinergic side effects
These TCAs more commonly cause anticholinergic side effects: - CORRECT
ANSWER ✔✔- amitriptyline, imipramine, clomipramine (Tertiary TCAs)
These are five main anticholinergic side effects: - CORRECT ANSWER ✔✔- dry
mouth, tachycardia, urinary retention, confusion, hallucinations (common with
Tertiary TCAs, amitriptyline, imipramine, clomipramine)
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MIDTERM STUDY GUIDE EXAM [VERSION A &
B] NEWEST 2026 ACTUAL EXAM COMPLETE
QUESTIONS AND CORRECT DETAILED
ANSWERS (VERIFIED ANSWERS) |ALREADY
GRADED A+||BRAND NEW!!
(WALDEN UNIVERSITY)
Adverse effects of MAOIs include: - CORRECT ANSWER ✔✔- Serotonin
syndrome and hypertensive crisis
Before starting another antidepressant MAOIs should be stopped for at least: -
CORRECT ANSWER ✔✔- Two weeks (to allow for the body to replace MAO
enzymes so that serotonin syndrome does not occur)
Five main symptoms of hypertensive crisis: - CORRECT ANSWER ✔✔-
hyperthermia, hypertension, tachycardia, arrhythmias, agitation
Hypertensive crisis commonly occurs when people taking MAOIs consume foods
or drinks high in: - CORRECT ANSWER ✔✔- tyramine (cheese, wine, beer,
cured/smoked meats)
Foods and drinks rich in tyramine: - CORRECT ANSWER ✔✔- cheese, wine,
beer, cured/smoked meats
1|Page
,When uninhibited, these two enzymes are responsible for breaking down tyramine:
- CORRECT ANSWER ✔✔- MAO-A and MAO-B
When tyramine is not broken down, it increases the release of this
neurotransmitter, which causes hypertensive crisis: - CORRECT ANSWER ✔✔-
Norepinephrine
Due to its action as an adrenergic antagonist this drug is the treatment of
hypertensive crisis: - CORRECT ANSWER ✔✔- Phentolamine
TCAs are subdivided into these two groups: - CORRECT ANSWER ✔✔- Tertiary
TCAs and Secondary TCAs
Three Tertiary TCAs: - CORRECT ANSWER ✔✔- amitriptyline, imipramine,
clomipramine
Two Secondary TCAs: - CORRECT ANSWER ✔✔- desipramine, nortriptyline
Tertiary TCAs are non-selective and act on: - CORRECT ANSWER ✔✔-
Serotonin and Norephinephrine transporters (increase 5HT and NE)
Secondary TCAs are selective and act only on: - CORRECT ANSWER ✔✔-
Norepinephrine transporters (increase NE)
Therapeutic benefits from TCAs typically take approximately: - CORRECT
ANSWER ✔✔- 2-4 weeks
2|Page
, In addition to treatment of depression, other indications for TCAs include: -
CORRECT ANSWER ✔✔- Phobic disorders, chronic neuropathic pain, migraine
prophylaxis
Medication specific indication for clomipramine: - CORRECT ANSWER ✔✔-
OCD
Medication specific indication for imipramine: - CORRECT ANSWER ✔✔-
Nocturnal enuresis
In addition to SERTs and NETs, TCAs block (causes side effects): - CORRECT
ANSWER ✔✔- Histamine (H1) receptors, Muscarinic receptors, and Alpha 1
receptors
TCAs inhibitory effects on Histamine (H1) receptors results in this side effect: -
CORRECT ANSWER ✔✔- sedation
TCAs inhibitory effects on Muscarinic receptors results in this side effect profile: -
CORRECT ANSWER ✔✔- anticholinergic side effects
These TCAs more commonly cause anticholinergic side effects: - CORRECT
ANSWER ✔✔- amitriptyline, imipramine, clomipramine (Tertiary TCAs)
These are five main anticholinergic side effects: - CORRECT ANSWER ✔✔- dry
mouth, tachycardia, urinary retention, confusion, hallucinations (common with
Tertiary TCAs, amitriptyline, imipramine, clomipramine)
3|Page
