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PAEA EOC Exam Study Resources | Updated 2025–2026

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Prepare for the PAEA EOC Exam with updated 2025–2026 study guides, review materials, and practice tools. Strengthen your knowledge and confidence for Physician Assistant program summative assessments.

Institution
Duke University
Course
PAEA EOC

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PAEA EOC EXAM (NEW UPDATED VERSION) LATEST ACTUAL EXAM QUESTIONS
AND CORRECT ANSWERS (VERIFIED QUESTIONS AND ANSWERS) | GUARANTEED
PASS A+ [2026]




1. A 67-year-old man presents with acute, sharp left-sided chest pain worsened by deep
inspiration. ECG shows diffuse ST elevations and PR depressions. What is the most likely
diagnosis?

Answer: Acute pericarditis
Rationale: Diffuse ST elevation with PR depression is classic for pericarditis, unlike MI, which
shows regional changes.



2. A patient with COPD has a PaCO₂ of 58 mmHg and bicarbonate of 34 mEq/L. What does this
pattern most likely represent?

Answer: Chronic respiratory acidosis with metabolic compensation
Rationale: Elevated PaCO₂ + compensatory ↑HCO₃⁻ suggests chronic CO₂ retention.



3. Which medication improves mortality in HFrEF (EF 30%)?

Answer: ACE inhibitors
Rationale: ACE-Is, ARBs, ARNI, β-blockers, aldosterone antagonists reduce mortality;
diuretics only improve symptoms.



4. First-line treatment for newly diagnosed Graves’ disease in pregnancy?

Answer: Propylthiouracil (PTU) in the first trimester
Rationale: PTU preferred early due to lower teratogenic risk vs methimazole.

,5. A patient with ascites and a SAAG of 1.8 g/dL likely has…

Answer: Portal hypertension
Rationale: SAAG ≥1.1 indicates portal hypertensive etiologies (cirrhosis, HF).



6. Best initial test for suspected pulmonary embolism in a hemodynamically stable patient?

Answer: CT pulmonary angiography
Rationale: CTPA is first-line unless contraindicated.



7. A diabetic patient with burning foot pain worse at night likely has…

Answer: Peripheral neuropathy
Rationale: Classic “stocking-glove” neuropathic symptoms.



8. Treatment for hypertensive emergency with acute aortic dissection?

Answer: IV β-blocker (esmolol)
Rationale: Reduces shear stress and heart rate before vasodilation.



9. Rheumatoid arthritis is most associated with which joint findings?

Answer: MCP and PIP involvement
Rationale: DIP involvement suggests osteoarthritis, not RA.



10. Kidney injury with granular casts (“muddy brown”) indicates…

Answer: Acute tubular necrosis
Rationale: Pathognomonic finding.




DOMAIN: SURGERY

, 11. A patient with sudden severe abdominal pain, rigid abdomen, and free air under the
diaphragm likely has…

Answer: Perforated viscus (e.g., peptic ulcer perforation)
Rationale: Free air suggests pneumoperitoneum.



12. Best treatment for acute cholecystitis?

Answer: Early laparoscopic cholecystectomy
Rationale: Standard of care unless unstable.



13. A postoperative patient with fever POD #1 most likely has…

Answer: Atelectasis
Rationale: Classic cause of early postoperative fever.



14. Most appropriate imaging for suspected appendicitis in adults?

Answer: CT abdomen/pelvis with contrast
Rationale: Most accurate in adults.



15. Suspected small bowel obstruction shows which radiographic findings?

Answer: Dilated loops with air-fluid levels
Rationale: Classic SBO pattern.




DOMAIN: PEDIATRICS
16. A 4-year-old with barking cough and inspiratory stridor likely has…

Answer: Croup
Rationale: Parainfluenza virus; steeple sign on X-ray.

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