KSA Asthma questions with detailed correct
answers.
A 26-year-old male with asthma is seen in the emergency department. He is short of breath to a
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degree that makes it difficult to speak in sentences and he appears tired. On examination you note
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
diminished breath sounds with an occasional wheeze. His FEV1 is 15% of predicted and his pCO2 is 45
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
mm Hg. He is given albuterol (Proventil, Ventolin) over the next hour but he has a poor response. He
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
is not able to repeat the spirometry and he now appears drowsy. Which one of the following would
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
be consistent with imminent respiratory failure? - ANS--E. The absence of wheezes
ss ss ss ss ss ss ss ss ss ss ss ss
Which one of the following is true regarding leukotriene modifiers for treatment of asthma in adults? -
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
ANS--D. They are less effective than inhaled corticosteroids (ICSs)
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Chronic low- to medium-dose inhaled corticosteroid use in children is associated with - ANS--E. no
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long-term adverse effects
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An 18-year-old female presents to your office with a history of wheezing, coughing, and year-round
ss ss ss ss ss ss ss ss ss ss ss ss ss ss
symptoms of rhinitis. She reports that her symptoms occur several times a week but rarely more than
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
once a day, except in the last year, when she has had to intermittently use albuterol (Proventil,
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
Ventolin) every day for a week at a time. She wakes up with nighttime coughing weekly, with no fever
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
or other symptoms, and tells you that the coughing is severe enough to make her cat jump off the
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
bed. Albuterol helps her symptoms temporarily. She has been treated with oral corticosteroids on
ss ss ss ss ss ss ss ss ss ss ss ss ss ss
three occasions this past year, most recently 6 weeks ago. Her Asthma Control Test score is 17. Pre-
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
and postbronchodilator spirometry results are shown below.
ss ss ss ss ss ss ss
Initial testing ss
FVC............2.0 L (80% of predicted) ss ss ss ss
FEV1............1.4 L (70% of predicted) ss ss ss ss
FEF 25-75............1.5 L/sec (89% of predicted)
ss ss ss ss ss
, 15 minutes post bronchodilator - ANS--A. Budesonide/formoterol (Symbicort), with an increase in
ss ss ss ss ss ss ss ss ss ss ss
dosage for exacerbations
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A 22-year-old female presents to your office with an acute asthma attack that developed 2 days after
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
the onset of a viral upper respiratory infection. Her asthma is usually well controlled, with a personal
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
best peak expiratory flow (PEF) of 380 L/min. On initial evaluation by the nurse she has a pulse rate of
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
120 beats/min, a respiratory rate of 32/min, and an oxygen saturation of 92% on room air. On
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
examination she is very dyspneic with diffuse inspiratory and expiratory wheezing and she is using
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
accessory muscles to breathe. Her PEF is 150 L/min. Inhaled β-agonists and systemic corticosteroids
ss ss ss ss ss ss ss ss ss ss ss ss ss ss
are administered and she is reevaluated 1 hour later. Which one of the following would provide the
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
most reassurance that she is responding to therapy? - ANS--C. A PEF of 310 L/min
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
You are counseling a patient with moderate persistent asthma about the value of following a written
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
asthma action plan. To encourage her to use an asthma action plan you share the results of studies
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
that document their benefit in optimizing asthma control and reducing future risk.
ss ss ss ss ss ss ss ss ss ss ss ss
Which one of the following is an accurate statement regarding asthma action plans? - ANS--D. The lack
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
of a written asthma action plan is a risk factor for death from asthma
ss ss ss ss ss ss ss ss ss ss ss ss ss ss
A 28-year-old female presents with progressively worsening asthma after a recent viral upper
ss ss ss ss ss ss ss ss ss ss ss ss
respiratory infection. When you enter the room, she appears in distress and is only able to talk in
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
words, not sentences. Her respiratory rate is 34/min and her heart rate is 126 beats/min. Her oxygen
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
saturation before oxygen was administered was 89%. You begin treatment with a nebulized short-
ss ss ss ss ss ss ss ss ss ss ss ss ss ss
acting β-agonist (SABA) plus ipratropium and give an initial dose of oral prednisone. After one hour her
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
symptoms are not responsive to initial treatment efforts.
ss ss ss ss ss ss ss ss
Which one of the following should you consider as a possible adjunctive treatment? - ANS--C.
ss ss ss ss ss ss ss ss ss ss ss ss ss ss
Intravenous magnesium sulfate
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Which one of the following is true regarding regular use of inhaled corticosteroids (ICSs) in patients
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
with persistent asthma? - ANS--A. Oral candidiasis is a potential side effect of ICS use
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
You have recently opened a new practice in western North Carolina. In your first week of seeing
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
patients, a 17-year-old male reports that his asthma is usually worse in the early spring.
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
answers.
A 26-year-old male with asthma is seen in the emergency department. He is short of breath to a
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
degree that makes it difficult to speak in sentences and he appears tired. On examination you note
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
diminished breath sounds with an occasional wheeze. His FEV1 is 15% of predicted and his pCO2 is 45
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
mm Hg. He is given albuterol (Proventil, Ventolin) over the next hour but he has a poor response. He
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
is not able to repeat the spirometry and he now appears drowsy. Which one of the following would
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
be consistent with imminent respiratory failure? - ANS--E. The absence of wheezes
ss ss ss ss ss ss ss ss ss ss ss ss
Which one of the following is true regarding leukotriene modifiers for treatment of asthma in adults? -
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
ANS--D. They are less effective than inhaled corticosteroids (ICSs)
ss ss ss ss ss ss ss ss ss
Chronic low- to medium-dose inhaled corticosteroid use in children is associated with - ANS--E. no
ss ss ss ss ss ss ss ss ss ss ss ss ss ss
long-term adverse effects
ss ss ss
An 18-year-old female presents to your office with a history of wheezing, coughing, and year-round
ss ss ss ss ss ss ss ss ss ss ss ss ss ss
symptoms of rhinitis. She reports that her symptoms occur several times a week but rarely more than
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
once a day, except in the last year, when she has had to intermittently use albuterol (Proventil,
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
Ventolin) every day for a week at a time. She wakes up with nighttime coughing weekly, with no fever
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
or other symptoms, and tells you that the coughing is severe enough to make her cat jump off the
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
bed. Albuterol helps her symptoms temporarily. She has been treated with oral corticosteroids on
ss ss ss ss ss ss ss ss ss ss ss ss ss ss
three occasions this past year, most recently 6 weeks ago. Her Asthma Control Test score is 17. Pre-
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
and postbronchodilator spirometry results are shown below.
ss ss ss ss ss ss ss
Initial testing ss
FVC............2.0 L (80% of predicted) ss ss ss ss
FEV1............1.4 L (70% of predicted) ss ss ss ss
FEF 25-75............1.5 L/sec (89% of predicted)
ss ss ss ss ss
, 15 minutes post bronchodilator - ANS--A. Budesonide/formoterol (Symbicort), with an increase in
ss ss ss ss ss ss ss ss ss ss ss
dosage for exacerbations
ss ss ss
A 22-year-old female presents to your office with an acute asthma attack that developed 2 days after
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
the onset of a viral upper respiratory infection. Her asthma is usually well controlled, with a personal
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
best peak expiratory flow (PEF) of 380 L/min. On initial evaluation by the nurse she has a pulse rate of
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
120 beats/min, a respiratory rate of 32/min, and an oxygen saturation of 92% on room air. On
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
examination she is very dyspneic with diffuse inspiratory and expiratory wheezing and she is using
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
accessory muscles to breathe. Her PEF is 150 L/min. Inhaled β-agonists and systemic corticosteroids
ss ss ss ss ss ss ss ss ss ss ss ss ss ss
are administered and she is reevaluated 1 hour later. Which one of the following would provide the
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
most reassurance that she is responding to therapy? - ANS--C. A PEF of 310 L/min
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
You are counseling a patient with moderate persistent asthma about the value of following a written
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
asthma action plan. To encourage her to use an asthma action plan you share the results of studies
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
that document their benefit in optimizing asthma control and reducing future risk.
ss ss ss ss ss ss ss ss ss ss ss ss
Which one of the following is an accurate statement regarding asthma action plans? - ANS--D. The lack
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
of a written asthma action plan is a risk factor for death from asthma
ss ss ss ss ss ss ss ss ss ss ss ss ss ss
A 28-year-old female presents with progressively worsening asthma after a recent viral upper
ss ss ss ss ss ss ss ss ss ss ss ss
respiratory infection. When you enter the room, she appears in distress and is only able to talk in
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
words, not sentences. Her respiratory rate is 34/min and her heart rate is 126 beats/min. Her oxygen
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
saturation before oxygen was administered was 89%. You begin treatment with a nebulized short-
ss ss ss ss ss ss ss ss ss ss ss ss ss ss
acting β-agonist (SABA) plus ipratropium and give an initial dose of oral prednisone. After one hour her
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
symptoms are not responsive to initial treatment efforts.
ss ss ss ss ss ss ss ss
Which one of the following should you consider as a possible adjunctive treatment? - ANS--C.
ss ss ss ss ss ss ss ss ss ss ss ss ss ss
Intravenous magnesium sulfate
ss ss ss
Which one of the following is true regarding regular use of inhaled corticosteroids (ICSs) in patients
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
with persistent asthma? - ANS--A. Oral candidiasis is a potential side effect of ICS use
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
You have recently opened a new practice in western North Carolina. In your first week of seeing
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
patients, a 17-year-old male reports that his asthma is usually worse in the early spring.
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss