ATI PN Pharmacology Proctored Exam
2025/2026 – Actual Test Bank with Verified
Questions & Rationales | Fully Updated
Section 1: General Pharmacology & Safety (1-10)
1. A nurse is preparing medications. Which actions are within legal guidelines? (SATA)
Maintain competency, determine dosage, monitor adverse effects, safeguard
medicationsRationale: RN responsibilities per Nurse Practice Act; never delegate IV
push.
2. Client with liver disease needs lower dose because: Decreased first-pass metabolism
3. Correct eye drop technique? (SATA) Look up, drop in conjunctival sac, close eye
gently
4. Before giving warfarin, check: INR
5. Giving insulin 1 hour early puts client at highest risk for: Hypoglycemia
6. Client teaching for atenolol: Monitor heart rate daily
7. Alendronate (Fosamax) teaching: Remain upright 30 minutes after dose
8. Common adverse effect of morphine: Constipation
9. True anaphylaxis sign with amoxicillin: Laryngeal edema
10. Priming blood tubing: 0.9% sodium chloride only
Section 2: Cardiovascular & Antihypertensives (11-25)
11. Lisinopril – monitor for: Hyperkalemia
12. Digoxin toxicity classic signs: Nausea, yellow vision halos
13. Opioid overdose reversal agent: Naloxone
14. Atorvastatin adverse effects (SATA): Muscle weakness, dark urine, dizziness
15. Nifedipine – primary assessment: Blood pressure
16. Epoetin alfa – do NOT let Hgb exceed: 11 g/dL
17. Aspirin contraindicated in children because of: Reye syndrome
18. Gentamicin monitoring: Nephrotoxicity (creatinine, trough levels)
19. Naproxen in elderly – highest risk: Acute kidney injury
20. Sodium polystyrene sulfonate – separate other oral meds by: At least 6 hours
21. DKA – expect: Hypokalemia after insulin starts
22. Bupropion XR titration schedule: 150 mg daily × 3 days, then increase
23. Nitrofurantoin contraindicated when CrCl is: < 60 mL/min
24. Vancomycin “red man” prevention: Infuse over 60–90 minutes
25. Clindamycin major risk: C. difficile colitis
Section 3: Antimicrobials & Anti-Infectives (26-40)
2025/2026 – Actual Test Bank with Verified
Questions & Rationales | Fully Updated
Section 1: General Pharmacology & Safety (1-10)
1. A nurse is preparing medications. Which actions are within legal guidelines? (SATA)
Maintain competency, determine dosage, monitor adverse effects, safeguard
medicationsRationale: RN responsibilities per Nurse Practice Act; never delegate IV
push.
2. Client with liver disease needs lower dose because: Decreased first-pass metabolism
3. Correct eye drop technique? (SATA) Look up, drop in conjunctival sac, close eye
gently
4. Before giving warfarin, check: INR
5. Giving insulin 1 hour early puts client at highest risk for: Hypoglycemia
6. Client teaching for atenolol: Monitor heart rate daily
7. Alendronate (Fosamax) teaching: Remain upright 30 minutes after dose
8. Common adverse effect of morphine: Constipation
9. True anaphylaxis sign with amoxicillin: Laryngeal edema
10. Priming blood tubing: 0.9% sodium chloride only
Section 2: Cardiovascular & Antihypertensives (11-25)
11. Lisinopril – monitor for: Hyperkalemia
12. Digoxin toxicity classic signs: Nausea, yellow vision halos
13. Opioid overdose reversal agent: Naloxone
14. Atorvastatin adverse effects (SATA): Muscle weakness, dark urine, dizziness
15. Nifedipine – primary assessment: Blood pressure
16. Epoetin alfa – do NOT let Hgb exceed: 11 g/dL
17. Aspirin contraindicated in children because of: Reye syndrome
18. Gentamicin monitoring: Nephrotoxicity (creatinine, trough levels)
19. Naproxen in elderly – highest risk: Acute kidney injury
20. Sodium polystyrene sulfonate – separate other oral meds by: At least 6 hours
21. DKA – expect: Hypokalemia after insulin starts
22. Bupropion XR titration schedule: 150 mg daily × 3 days, then increase
23. Nitrofurantoin contraindicated when CrCl is: < 60 mL/min
24. Vancomycin “red man” prevention: Infuse over 60–90 minutes
25. Clindamycin major risk: C. difficile colitis
Section 3: Antimicrobials & Anti-Infectives (26-40)
