NCLEX-Style Pharmacology Exam – 2025
| 100 Comprehensive Q&A with
Rationales| Grade A | 100% Correct -
The Ultimate Guide for Yr. (2026/2027)
1. Q1. A patient receiving norepinephrine develops cold, pale extremities. What is the nurse’s
priority action? (Var 24)
• A. Administer oxygen at 2L via nasal cannula.
• B. Discontinue the infusion and notify the provider.
• C. Elevate the extremities above the heart.
• D. Apply warm compresses to the extremities.
Correct Answer: B
Rationale: Norepinephrine can cause vasoconstriction leading to ischemia. Signs of perfusion
loss require immediate discontinuation of the drug.
2. Q2. What is the primary purpose of administering epinephrine during anaphylaxis? (Var 18)
• A. Reduce inflammation
• B. Stimulate immune response
• C. Open the airway and raise blood pressure
• D. Block histamine release
Correct Answer: C
Rationale: Epinephrine stimulates alpha and beta receptors, causing bronchodilation and
vasoconstriction to treat airway obstruction and hypotension.
3. Q3. A patient receiving norepinephrine develops cold, pale extremities. What is the nurse’s
priority action? (Var 10)
• A. Administer oxygen at 2L via nasal cannula.
1
, • B. Discontinue the infusion and notify the provider.
• C. Elevate the extremities above the heart.
• D. Apply warm compresses to the extremities.
Correct Answer: B
Rationale: Norepinephrine can cause vasoconstriction leading to ischemia. Signs of perfusion
loss require immediate discontinuation of the drug.
4. Q4. Which medication should be administered prior to surgery to reduce oral secretions?
(Var 15)
• A. Atropine
• B. Albuterol
• C. Diphenhydramine D. Tamsulosin
Correct Answer: A
Rationale: Atropine is an anticholinergic used to decrease secretions before anesthesia or
surgery.
5. Q5. A patient receiving norepinephrine develops cold, pale extremities. What is the nurse’s
priority action? (Var 22)
• A. Administer oxygen at 2L via nasal cannula.
• B. Discontinue the infusion and notify the provider.
• C. Elevate the extremities above the heart.
• D. Apply warm compresses to the extremities.
Correct Answer: B
Rationale: Norepinephrine can cause vasoconstriction leading to ischemia. Signs of perfusion
loss require immediate discontinuation of the drug.
6. Q6. A patient receiving norepinephrine develops cold, pale extremities. What is the nurse’s
priority action? (Var 20)
• A. Administer oxygen at 2L via nasal cannula.
• B. Discontinue the infusion and notify the provider.
• C. Elevate the extremities above the heart.
• D. Apply warm compresses to the extremities.
Correct Answer: B
2
, Rationale: Norepinephrine can cause vasoconstriction leading to ischemia. Signs of perfusion
loss require immediate discontinuation of the drug.
7. Q7. A patient receiving norepinephrine develops cold, pale extremities. What is the nurse’s
priority action? (Var 18)
• A. Administer oxygen at 2L via nasal cannula.
• B. Discontinue the infusion and notify the provider.
• C. Elevate the extremities above the heart.
• D. Apply warm compresses to the extremities.
Correct Answer: B
Rationale: Norepinephrine can cause vasoconstriction leading to ischemia. Signs of perfusion
loss require immediate discontinuation of the drug.
8. Q8. A patient on theophylline has a serum level of 22 mcg/mL. What is the nurse's priority
action? (Var 7)
• A. Continue medication as ordered.
• B. Increase fluid intake to promote excretion.
• C. Notify the provider of possible toxicity. D. Administer a bronchodilator.
Correct Answer: C
Rationale: Therapeutic range for theophylline is 10–20 mcg/mL. A level of 22 suggests toxicity
requiring provider notification.
9. Q9. A patient on theophylline has a serum level of 22 mcg/mL. What is the nurse's priority
action? (Var 5)
• A. Continue medication as ordered.
• B. Increase fluid intake to promote excretion.
• C. Notify the provider of possible toxicity. D. Administer a bronchodilator.
Correct Answer: C
Rationale: Therapeutic range for theophylline is 10–20 mcg/mL. A level of 22 suggests toxicity
requiring provider notification.
10. Q10. What is the primary purpose of administering epinephrine during anaphylaxis? (Var 21)
3
| 100 Comprehensive Q&A with
Rationales| Grade A | 100% Correct -
The Ultimate Guide for Yr. (2026/2027)
1. Q1. A patient receiving norepinephrine develops cold, pale extremities. What is the nurse’s
priority action? (Var 24)
• A. Administer oxygen at 2L via nasal cannula.
• B. Discontinue the infusion and notify the provider.
• C. Elevate the extremities above the heart.
• D. Apply warm compresses to the extremities.
Correct Answer: B
Rationale: Norepinephrine can cause vasoconstriction leading to ischemia. Signs of perfusion
loss require immediate discontinuation of the drug.
2. Q2. What is the primary purpose of administering epinephrine during anaphylaxis? (Var 18)
• A. Reduce inflammation
• B. Stimulate immune response
• C. Open the airway and raise blood pressure
• D. Block histamine release
Correct Answer: C
Rationale: Epinephrine stimulates alpha and beta receptors, causing bronchodilation and
vasoconstriction to treat airway obstruction and hypotension.
3. Q3. A patient receiving norepinephrine develops cold, pale extremities. What is the nurse’s
priority action? (Var 10)
• A. Administer oxygen at 2L via nasal cannula.
1
, • B. Discontinue the infusion and notify the provider.
• C. Elevate the extremities above the heart.
• D. Apply warm compresses to the extremities.
Correct Answer: B
Rationale: Norepinephrine can cause vasoconstriction leading to ischemia. Signs of perfusion
loss require immediate discontinuation of the drug.
4. Q4. Which medication should be administered prior to surgery to reduce oral secretions?
(Var 15)
• A. Atropine
• B. Albuterol
• C. Diphenhydramine D. Tamsulosin
Correct Answer: A
Rationale: Atropine is an anticholinergic used to decrease secretions before anesthesia or
surgery.
5. Q5. A patient receiving norepinephrine develops cold, pale extremities. What is the nurse’s
priority action? (Var 22)
• A. Administer oxygen at 2L via nasal cannula.
• B. Discontinue the infusion and notify the provider.
• C. Elevate the extremities above the heart.
• D. Apply warm compresses to the extremities.
Correct Answer: B
Rationale: Norepinephrine can cause vasoconstriction leading to ischemia. Signs of perfusion
loss require immediate discontinuation of the drug.
6. Q6. A patient receiving norepinephrine develops cold, pale extremities. What is the nurse’s
priority action? (Var 20)
• A. Administer oxygen at 2L via nasal cannula.
• B. Discontinue the infusion and notify the provider.
• C. Elevate the extremities above the heart.
• D. Apply warm compresses to the extremities.
Correct Answer: B
2
, Rationale: Norepinephrine can cause vasoconstriction leading to ischemia. Signs of perfusion
loss require immediate discontinuation of the drug.
7. Q7. A patient receiving norepinephrine develops cold, pale extremities. What is the nurse’s
priority action? (Var 18)
• A. Administer oxygen at 2L via nasal cannula.
• B. Discontinue the infusion and notify the provider.
• C. Elevate the extremities above the heart.
• D. Apply warm compresses to the extremities.
Correct Answer: B
Rationale: Norepinephrine can cause vasoconstriction leading to ischemia. Signs of perfusion
loss require immediate discontinuation of the drug.
8. Q8. A patient on theophylline has a serum level of 22 mcg/mL. What is the nurse's priority
action? (Var 7)
• A. Continue medication as ordered.
• B. Increase fluid intake to promote excretion.
• C. Notify the provider of possible toxicity. D. Administer a bronchodilator.
Correct Answer: C
Rationale: Therapeutic range for theophylline is 10–20 mcg/mL. A level of 22 suggests toxicity
requiring provider notification.
9. Q9. A patient on theophylline has a serum level of 22 mcg/mL. What is the nurse's priority
action? (Var 5)
• A. Continue medication as ordered.
• B. Increase fluid intake to promote excretion.
• C. Notify the provider of possible toxicity. D. Administer a bronchodilator.
Correct Answer: C
Rationale: Therapeutic range for theophylline is 10–20 mcg/mL. A level of 22 suggests toxicity
requiring provider notification.
10. Q10. What is the primary purpose of administering epinephrine during anaphylaxis? (Var 21)
3
