UPDATE!!!!!2025/2026|GUARANTEED
True statements related to drug dose calculation and administration - ANSWER 1)
Appropriateness of treatment regiment for this type/stage of disease
2) Children may metabolize drugs differently than adults; dose modifications are possible
3)AUC calculations incorporate renal function as part of the equation
4) The AUC calculation is used for carboplatin dosing
5) Patients who have had previous radiation or chemo are considered special populations
with regard to a potential need for dose modification
Based on ASCO/ONS Chemo Administration Standards, two independent practitioners, in the
presence of the patient, must verify the patient's identification using at least two patient
identifiers - ANSWER True, and verification should be made by two independent
practitioners upon drug preparation and prior to administration under all circumstances
Rituximab - ANSWER Hypersensitivity Reaction - SOB, cx pain, itching, hypotension,
tachycardia, wheezing, edema, agitation
Cyclophosphamide - ANSWER alkylating agent, can cause hemorrhagic cystitis.
Monitor for hematuria and give extra fluids. Urinate frequently, urinate before bedtime,
drink 2-3 L of water daily. Premedicate with Mesna and IV fluids. Myelosuppression and
SIADH may occur.
Doxorubicin - ANSWER Cardiotoxicity, monitor cumulative dose, MUGA scan to
evaluate EF. This is vesicant.
1
True statements related to drug dose calculation and administration - ANSWER 1)
Appropriateness of treatment regiment for this type/stage of disease
2) Children may metabolize drugs differently than adults; dose modifications are possible
3)AUC calculations incorporate renal function as part of the equation
4) The AUC calculation is used for carboplatin dosing
5) Patients who have had previous radiation or chemo are considered special populations
with regard to a potential need for dose modification
Based on ASCO/ONS Chemo Administration Standards, two independent practitioners, in the
presence of the patient, must verify the patient's identification using at least two patient
identifiers - ANSWER True, and verification should be made by two independent
practitioners upon drug preparation and prior to administration under all circumstances
Rituximab - ANSWER Hypersensitivity Reaction - SOB, cx pain, itching, hypotension,
tachycardia, wheezing, edema, agitation
Cyclophosphamide - ANSWER alkylating agent, can cause hemorrhagic cystitis.
Monitor for hematuria and give extra fluids. Urinate frequently, urinate before bedtime,
drink 2-3 L of water daily. Premedicate with Mesna and IV fluids. Myelosuppression and
SIADH may occur.
Doxorubicin - ANSWER Cardiotoxicity, monitor cumulative dose, MUGA scan to
evaluate EF. This is vesicant.
1
