PHARMACOLOGY NR566 FINAL EXAM
QUESTIONS & VERIFIED CORRECT
ANSWERS
For treatment of existing osteoporosis, the dose of alendronate - correct answer ✔✔10 mg/day
or 70 mg/week
Initial dosage for bone less prevention alendronate and risedronate - correct answer ✔✔5
mg/day or 35 mg/week
For treatment of existing osteoporosis, the dose of risedronate - correct answer ✔✔75 mg for 2
consecutive days or 150 mg once a month
Alendronate (Fosamax) - correct answer ✔✔Therapy with 10 mg daily can increase bone
density by up to 10% after 3 years and can decrease vertebral and hip fractures by 50%
Testosterone replacement therapy - correct answer ✔✔risk of prostate cancer
Testosterone replacement therapy - correct answer ✔✔Erythrocytosis is a risk; Hgb and Hct
levels checked, expect increase first 6 mths, unless Hgb level higher than 17.5 g/dL, Hct higher
than 54%, or both suggests overtreatment or occasionally abuse. IM happens more than
transdermal. If the Hct is greater than 54%, therapy is stopped until the Hct decreases to a safe
level. The patient should also be evaluated for hypoxia and sleep apnea. Restarting therapy at a
reduced dose usually solves problems.
Adults with vitamin B12 deficiency that is not pernicious anemia - correct answer ✔✔1,000 mcg
of oral cobalamin are given until normal B12 levels are achieved—usually 6 to 12 weeks. In
seriously ill patients, both vitamin B12 and folic acid may need to be administered.
, Who cannot get TRT - correct answer ✔✔breast cancer in a male patient, prostrate cancer,
polycythemia vera, increased calcium in the blood from cancer, diabetes, high cholesterol,
overweight and high blood pressure
BC contraindications - correct answer ✔✔Age >40 yr or Smoker <35 yr
BMI >30 due to increased VTE risk
HTN or hyperlipidemia
First-degree relative with DVT/PE
Major surgery without prolonged immobilization
Superficial thrombophlebitis
SLE on immunosuppressive therapy or with severe thrombocytopenia
Rheumatoid arthritis Sickle cell disease
BC contraindications - correct answer ✔✔Valvular heart disease, uncomplicated
Migraine without neurological aura, age <35 yr
Unexplained vaginal bleeding, suspicious for serious underlying condition
Cervical intraepithelial neoplasia
Cervical cancer, awaiting treatment
Undiagnosed breast mass
BC contraindications - correct answer ✔✔Diabetes, insulin dependent or non-insulin-
dependent, without vascular disease
Asymptomatic gallbladder disease or postcholecystectomy
Benign focal nodular hyperplasia of the liver
Hx of cholestasis in pregnancy
Ulcerative colitis or Crohn's disease
QUESTIONS & VERIFIED CORRECT
ANSWERS
For treatment of existing osteoporosis, the dose of alendronate - correct answer ✔✔10 mg/day
or 70 mg/week
Initial dosage for bone less prevention alendronate and risedronate - correct answer ✔✔5
mg/day or 35 mg/week
For treatment of existing osteoporosis, the dose of risedronate - correct answer ✔✔75 mg for 2
consecutive days or 150 mg once a month
Alendronate (Fosamax) - correct answer ✔✔Therapy with 10 mg daily can increase bone
density by up to 10% after 3 years and can decrease vertebral and hip fractures by 50%
Testosterone replacement therapy - correct answer ✔✔risk of prostate cancer
Testosterone replacement therapy - correct answer ✔✔Erythrocytosis is a risk; Hgb and Hct
levels checked, expect increase first 6 mths, unless Hgb level higher than 17.5 g/dL, Hct higher
than 54%, or both suggests overtreatment or occasionally abuse. IM happens more than
transdermal. If the Hct is greater than 54%, therapy is stopped until the Hct decreases to a safe
level. The patient should also be evaluated for hypoxia and sleep apnea. Restarting therapy at a
reduced dose usually solves problems.
Adults with vitamin B12 deficiency that is not pernicious anemia - correct answer ✔✔1,000 mcg
of oral cobalamin are given until normal B12 levels are achieved—usually 6 to 12 weeks. In
seriously ill patients, both vitamin B12 and folic acid may need to be administered.
, Who cannot get TRT - correct answer ✔✔breast cancer in a male patient, prostrate cancer,
polycythemia vera, increased calcium in the blood from cancer, diabetes, high cholesterol,
overweight and high blood pressure
BC contraindications - correct answer ✔✔Age >40 yr or Smoker <35 yr
BMI >30 due to increased VTE risk
HTN or hyperlipidemia
First-degree relative with DVT/PE
Major surgery without prolonged immobilization
Superficial thrombophlebitis
SLE on immunosuppressive therapy or with severe thrombocytopenia
Rheumatoid arthritis Sickle cell disease
BC contraindications - correct answer ✔✔Valvular heart disease, uncomplicated
Migraine without neurological aura, age <35 yr
Unexplained vaginal bleeding, suspicious for serious underlying condition
Cervical intraepithelial neoplasia
Cervical cancer, awaiting treatment
Undiagnosed breast mass
BC contraindications - correct answer ✔✔Diabetes, insulin dependent or non-insulin-
dependent, without vascular disease
Asymptomatic gallbladder disease or postcholecystectomy
Benign focal nodular hyperplasia of the liver
Hx of cholestasis in pregnancy
Ulcerative colitis or Crohn's disease
