NR 566 WEEK 1 EXAM QUESTIONS &
VERIFIED COMPLETE ANSWERS
100%
What are the major antibiotic drug classes - correct answer ✔✔Beta-lactams: penicillins
Beta-lactams: Cephalosporins
fluoroquinolones
tetracyclines and macrolides
sulfonamides, trimethoprim, &nitrofurantoin
What is the primary goal of antibiotic therapy - correct answer ✔✔kill bacteria without harming
host tissue
Bactericidal antibiotics - correct answer ✔✔directly kill bacteria
bacteriostatic antibiotics - correct answer ✔✔Antibiotics that do not actually kill bacteria but
rather inhibit bacterial proliferation while the hosts immune system does the killing
which antibiotics are preferred for immunocompromised patients: bactericidal or bacteriostatic
- correct answer ✔✔bactericidal
which antibiotics are preferred for patients with an overwhelming infection: bactericidal or
bacteriostatic - correct answer ✔✔bactericidal
broad spectrum antibiotics - correct answer ✔✔affect a broad range of gram-positive or gram-
negative bacteria
,narrow spectrum antibiotics - correct answer ✔✔Effective against specific bacteria
which is used for empiric therapy: narrow or broad - correct answer ✔✔broad spectrum
Risks of Broad Spectrum - correct answer ✔✔disruption of normal floral
increases risk of development of antibiotic resistance
which antibiotics increase the risk of antibiotic resistance: narrow or broad spectrum and why -
correct answer ✔✔Broad spectrum because they kill more competing organisms than narrow
spectrum drugs
is narrow or broad spectrum antibiotics preferred - correct answer ✔✔narrow is preferred
when possible.
broad spectrum only used when pathogen is unknown or when multiple types of bacteria is
suspected
Bactericidal drugs - correct answer ✔✔Aminoglycosides
Beta-lactams
fluoroquinolones
Metronidazole
Vancomycin
streptogramins
most antimycobacterial agents (rifampin, isoniazid, streptomycin, etc)
bacteriostatic drugs - correct answer ✔✔clindamycin
, macrolides
sulfonamides
tetracyclines
When is empiric therapy used? - correct answer ✔✔when treatment is started without cultures
or when culture results are not back yet
who needs empiric therapy - correct answer ✔✔critically ill pts after first set of cxs
hospitalized pts until css are available
ambulatory pts based on clinical presentation
Penicillins MOA - correct answer ✔✔inhibit cell wall synthesis; bactericidal
penicillins primarily excreted how - correct answer ✔✔in urine
what needs to be monitored when giving penicillins - correct answer ✔✔renal function
what happens if renal insufficiency occurs while giving penicillins - correct answer
✔✔prolonged half-life leading to toxicity
Penicillin distribution - correct answer ✔✔-Well distributed to most body tissues
-Penetration to CSF and eye tissues poor in absence of inflammation
narrow-spectrum penicillinase sensitive drugs - correct answer ✔✔penicillin G
penicillin V
VERIFIED COMPLETE ANSWERS
100%
What are the major antibiotic drug classes - correct answer ✔✔Beta-lactams: penicillins
Beta-lactams: Cephalosporins
fluoroquinolones
tetracyclines and macrolides
sulfonamides, trimethoprim, &nitrofurantoin
What is the primary goal of antibiotic therapy - correct answer ✔✔kill bacteria without harming
host tissue
Bactericidal antibiotics - correct answer ✔✔directly kill bacteria
bacteriostatic antibiotics - correct answer ✔✔Antibiotics that do not actually kill bacteria but
rather inhibit bacterial proliferation while the hosts immune system does the killing
which antibiotics are preferred for immunocompromised patients: bactericidal or bacteriostatic
- correct answer ✔✔bactericidal
which antibiotics are preferred for patients with an overwhelming infection: bactericidal or
bacteriostatic - correct answer ✔✔bactericidal
broad spectrum antibiotics - correct answer ✔✔affect a broad range of gram-positive or gram-
negative bacteria
,narrow spectrum antibiotics - correct answer ✔✔Effective against specific bacteria
which is used for empiric therapy: narrow or broad - correct answer ✔✔broad spectrum
Risks of Broad Spectrum - correct answer ✔✔disruption of normal floral
increases risk of development of antibiotic resistance
which antibiotics increase the risk of antibiotic resistance: narrow or broad spectrum and why -
correct answer ✔✔Broad spectrum because they kill more competing organisms than narrow
spectrum drugs
is narrow or broad spectrum antibiotics preferred - correct answer ✔✔narrow is preferred
when possible.
broad spectrum only used when pathogen is unknown or when multiple types of bacteria is
suspected
Bactericidal drugs - correct answer ✔✔Aminoglycosides
Beta-lactams
fluoroquinolones
Metronidazole
Vancomycin
streptogramins
most antimycobacterial agents (rifampin, isoniazid, streptomycin, etc)
bacteriostatic drugs - correct answer ✔✔clindamycin
, macrolides
sulfonamides
tetracyclines
When is empiric therapy used? - correct answer ✔✔when treatment is started without cultures
or when culture results are not back yet
who needs empiric therapy - correct answer ✔✔critically ill pts after first set of cxs
hospitalized pts until css are available
ambulatory pts based on clinical presentation
Penicillins MOA - correct answer ✔✔inhibit cell wall synthesis; bactericidal
penicillins primarily excreted how - correct answer ✔✔in urine
what needs to be monitored when giving penicillins - correct answer ✔✔renal function
what happens if renal insufficiency occurs while giving penicillins - correct answer
✔✔prolonged half-life leading to toxicity
Penicillin distribution - correct answer ✔✔-Well distributed to most body tissues
-Penetration to CSF and eye tissues poor in absence of inflammation
narrow-spectrum penicillinase sensitive drugs - correct answer ✔✔penicillin G
penicillin V
